Process for preparing compound iodine disinfectant

A preparation process and technology for disinfectant, applied in the direction of disinfectants, medical preparations with no active ingredients, medical preparations containing active ingredients, etc., can solve the problems of reduced effective content and poor stability of iodine and chlorhexidine acetate, etc. Achieve the effect of avoiding complexation and promoting solution stability

Inactive Publication Date: 2014-08-20
山东安捷高科消毒科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The invention provides a preparation process of an iodine compound disinfectant to solve the problems in the prior art that iodine and chlorhexidine acetate are easy to form complexes, resulting in reduced effective content and poor stability of iodine and chlorhexidine acetate

Method used

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Examples

Experimental program
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Effect test

example 1

[0010] A preparation process of iodine compound disinfectant, adopting povidone iodine instead of elemental iodine, the iodine mass content in povidone iodine is 8.2%, 1.87kg povidone iodine is dissolved in 31.5kg water to form A solution; use octyl Phenol polyoxyethylene ether solution dissolves 0.5kg chlorhexidine acetate to form B solution, the mass content of chlorhexidine acetate is 99%, mix A solution and B solution, then add 63.5kg water and mix evenly to make 100L iodine compound disinfectant.

example 2

[0012] A preparation process of iodine compound disinfectant, adopting povidone iodine instead of elemental iodine, the mass content of iodine in povidone iodine is 10.68%, 1.87kg povidone iodine is dissolved in 31.5kg water to form A solution; use 15kg95% 0.5kg of chlorhexidine acetate is dissolved by alcohol to form solution B, the mass content of chlorhexidine acetate is 99%, solution A and solution B are mixed, then 53.5kg of alcohol is added and mixed evenly to make 100L iodine compound disinfectant.

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PUM

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Abstract

The invention discloses a process for preparing a compound iodine disinfectant. The process comprises the following steps: substituting elemental iodine by adopting povidone-iodine, and dissolving povidone-iodine to form a solution A by using water; dissolving chlorhexidine acetate to form a solution B by using a solvent, mixing the solution A and the solution B, and preparing the compound iodine disinfectant. According to the method, the elemental iodine is substituted by adopting povidone-iodine, and chlorhexidine acetate is dissolved by using a solvent, namely octaphenyl polyoxyethyiene solution or alcoholic solution, so that complexing between the elemental iodine and chlorhexidine acetate is avoided, the content of free iodine and chlorhexidine acetate in the compound iodine disinfectant is ensured, and the solution stability of povidone-iodine and chlorhexidine acetate can be promoted.

Description

technical field [0001] The invention relates to the technical field of disinfectant production, in particular to a preparation process of iodine compound disinfectant. Background technique [0002] Iodine is a commonly used disinfectant and can be widely used in the disinfection of skin, mucous membranes, instruments and articles. Its bactericidal mechanism is generally believed to be based on the iodination of iodine and the destruction of the outer layer of cells. Free iodine can directly react with bacterial proteins and bacterial enzyme proteins, destroying the biological activity of proteins and leading to the death of microorganisms. Chlorhexidine acetate is a cationic surfactant with a broad antibacterial spectrum. It has a killing effect on most Gram-positive and negative bacteria, and is also effective against Pseudomonas aeruginosa. It can be used for disinfection of hands, skin, planes and instruments before surgery. The main effective components of the current i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N59/12A01N25/02A01P1/00A61K31/79A61K9/08A61K47/34A61K47/10A61P31/04A01N47/44A61K31/155
Inventor 刘峰董淑芹
Owner 山东安捷高科消毒科技有限公司
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