Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

33results about How to "Avoid complexation" patented technology

Grafted cyclodextrin

Thermoplastic polymer compositions, films, continues, closures, laminates can comprise a modified vinyl polymer said modified polymer having a moiety comprising a cyclodextrin compound. The cyclodextrin compound, locked into the polymer structure, can absorb impurities, permeants, or other undesirable volatile materials. The cooperation between the cyclodextrin grafted onto the thermoplastic polymer and the polymer structure can provide barrier properties to a film, web or other polymer structure. A permeant or a contaminant can be complexed or trapped within the polymer and held within the film or Web preventing the permeant or contaminant from passing into the interior of a container or enclosure.
Owner:VERDANT TECH LLC

Grafted cyclodextrin

Thermoplastic polymer compositions, films, continues, closures, laminates can comprise a modified vinyl polymer said modified polymer having a moiety comprising a cyclodextrin compound. The cyclodextrin compound, locked into the polymer structure, can absorb impurities, permeants, or other undesirable volatile materials. The cooperation between the cyclodextrin grafted onto the thermoplastic polymer and the polymer structure can provide barrier properties to a film, web or other polymer structure. A permeant or a contaminant can be complexed or trapped within the polymer and held within the film or Web preventing the permeant or contaminant from passing into the interior of a container or enclosure.
Owner:VERDANT TECH LLC

Grafted cyclodextrin

Thermoplastic polymer compositions, films, continues, closures, laminates can comprise a modified vinyl polymer said modified polymer having a moiety comprising a cyclodextrin compound. The cyclodextrin compound, locked into the polymer structure, can absorb impurities, permeants, or other undesirable volatile materials. The cooperation between the cyclodextrin grafted onto the thermoplastic polymer and the polymer structure can provide barrier properties to a film, web or other polymer structure. A permeant or a contaminant can be complexed or trapped within the polymer and held within the film or Web preventing the permeant or contaminant from passing into the interior of a container or enclosure.
Owner:VERDANT TECH LLC

Preparation method of graphene oxide enhanced cement-based mortar material

ActiveCN108424085ASolve the problem of agglomeration and flocculationExcellent flexural compressive strengthFlocculationGraphene
The invention discloses a preparation method of a graphene oxide enhanced cement-based mortar material. According to the method, an addition manner of graphene oxide is changed. The method comprises the following steps: rapidly freezing aqueous dispersion of graphene oxide with liquid nitrogen; crushing graphene oxide dispersion ice blocks, and gradually adding standard sand and cement in the process; finally, uniformly stirring the mixture, thereby obtaining the graphene oxide enhanced cement-based mortar material. According to the method disclosed by the invention, the graphene oxide can beuniformly dispersed in a cement matrix, the complexing action between the graphene oxide and calcium ions is well solved, a flocculation phenomenon of the graphene oxide in cement paste is effectivelyavoided, and excellent performance of the graphene oxide is further fully achieved. Moreover, any other dispersing agent does not need to be added, and introduction of impurities is reduced. The method disclosed by the invention provides a novel research thought for preparation of the graphene oxide enhanced cement-based mortar material.
Owner:张翼航

Preparation method of 2-methyl-4-acetoxy-2-butenal with high yield

The invention provides a preparation method of 2-methyl-4-acetoxy-2-butenal (I) with high yield. The preparation method comprises the steps: with 2,5-dihydrofuran (II) and synthesis gas as raw materials, carrying out hydroformylation reaction under the action of a catalyst to prepare 3-formyl tetrahydrofuran (III); then carrying out a reaction with an acetylation reagent under the action of a catalyst to prepare 2-formyl-4-acetoxy-1-butene (IV); and carrying out double bond isomerization under the action of a catalyst to obtain 2-methyl-4-acetoxy-2-butenal (I). The method has the advantages ofcheap and accessible raw materials and low cost; the process flow is short, the reaction is easy to realize, the operation is safe, simple and convenient, the wastewater yield is low, and the green and environment-friendly effects are achieved; the method has the advantages of stable reaction intermediate product, proper reaction activity, high reaction selectivity, fewer side reactions and highyield, and is suitable for industrial production.
Owner:XINFA PHARMA

Mother solution of standard solution for chromatography of heavy metals in leather and preparation method of standard curve

The invention relates to a technology for fast determination of heavy metals in leather and particularly relates to a standard curve for fast determination of heavy metals in leather by X-ray fluorescence energy spectrum analysis and a mother solution of the standard solution, which is used for preparing the standard curve. The mother solution of the standard solution is prepared from a leather penetrating agent, phosphoric acid, nitric acid and the national standard solution of nine heavy metals. A method for preparing the standard curve comprises the following steps: (1) preparing the mother solution of the standard solution; (2) preparing a multi-gradient standard solution; (3) preparing a series of standard test samples of the heavy metals in the leather; (4) preparing circular sheets of the standard test samples to be tested of the leather; (5) detecting by X-ray fluorescence chromatography; (6) drawing the standard curve. The technology provided by the invention has the advantages that the detection precision of the nine heavy metal harmful substances in the leather can be improved to meet the requirements of a national standard, thus the advanced technology of the X-ray fluorescence chromatography can be applied to detection of the nine heavy metal harmful substances in the leather.
Owner:SICHUAN ENTRY EXIT INSPECTION & QUARANTINE BUREAU INSPECTION & QUARANTINE TECHN CENT

Identification of compounds for inhibiting complexation of C-reactive protein with fibronectin

Disclosed are screening processes for identification of compounds that may inhibit complex formation between C-reactive protein and fibronectin. Compounds identified by the disclosed methods may be utilized to inhibit the target analytes that are known to occur during skin aging as well as during the course of several diseases. Accordingly, inhibitory compounds identified by the disclosed methods may be utilized to prevent and treat damaged tissue, inflammatory conditions, cardiovascular conditions, renal conditions, periodontal conditions and obesity, among other conditions. For example, the compounds identified by the disclosed methods may be utilized to treat tissue that has suffered trauma, e.g., burns or wounds, as well as tissue that is inflamed due to any of several causes. The disclosed compounds may also be utilized to improve the accuracy of assays designed to assess CRP or Fn levels in a sample, for instance in a plasma sample, as a risk assessment tool in certain medical conditions and to discover new treatments.
Owner:KIMBERLY-CLARK WORLDWIDE INC

Brown waste liquid treatment device and brown waste liquid treatment method

The invention is applicable to the field of waste water treatment, and provides a brown waste liquid treatment device. The brown waste liquid treatment device comprises a storage device for storing brown waste liquid, an electrolyzer used for electrolytic treatment of the brown waste liquid, and a COD (chemical oxygen demand) degradation device for oxidizing the brown waste liquid. The COD degradation device is connected between the storage device and the electrolyzer. The invention further provides a brown waste liquid treatment method. The brown waste liquid treatment device has the advantages that the COD degradation device is used for oxidizing the brown waste liquid before electrolytic treatment, and copper type slow-release agents such as 1H-benzotriazole in the brown waste liquid can be oxidized, so that bright blocky high-quality copper with high purity can be obtained.
Owner:SHENZHEN JECH TECH

Method for synthesizing polysubstituted amino isoquinoline compound by cyclizing pyridine and alkyne under catalysis of rhodium

The invention discloses a method for synthesizing a polysubstituted aminoisoquinoline compound by cyclizing pyridine and alkyne under the catalysis of rhodium, which comprises the following steps: byusing a pentamethylcyclopentadienyl rhodium complex as a catalyst and a 2-aminopyridine derivative and an internal alkyne compound as raw materials, reacting in an organic solvent at 30-150 DEG C for1-24 hours, cooling the reaction solution after the reaction is finished, removing the organic solvent under reduced pressure; purifying the crude product through a silicon dioxide column, and elutingwith petroleum ether / ethyl acetate to obtain the pure polysubstituted aminoisoquinoline derivative. According to the method, a guide group (carbonyl) or a steric hindrance group (methyl) is introduced into the reaction to realize C-H bond activation and avoid the coordination effect of pyridine on the metal catalyst, and the regulation and control of the reaction activity and selectivity are efficiently realized through the regulation and control of the group with large steric hindrance. The obtained generation target products are high in selectivity, and the selectivity is 90% or above, byproducts are few, and the product separation cost is reduced, and the method is simple in synthesis process, mild in reaction condition and convenient for industrial production.
Owner:LANZHOU INST OF CHEM PHYSICS CHINESE ACAD OF SCI

Method for analyzing contents of fluorides in hazardous wastes

The invention provides a method for analyzing the contents of fluorides in hazardous wastes. According to the method, a pretreated sample is completely combusted in an enclosed space by adoption of anoxygen bomb combustion technology; one part of the fluorine element in the oxygen bomb is absorbed by absorption liquid in the oxygen bomb and the other part is absorbed by absorption liquid in a gasabsorption station through a gas form; the absorption liquid is combined to obtain fluoride extracting solution; and the extracting solution is treated to obtain to-be-tested sample solution. Fluorine ion series standard solution is prepared; and a standard curve is drawn for a negative logarithm (E(Mv)-log cF-(mg / L))of the concentration of fluorine ions via a potential value E. An ion chromatograph-fluoride ion selective electrode is utilized to measure the potential value of the to-be-tested sample solution; and the content of the fluorides is calculated via the standard curve according tothe measured potential value. The method is relatively high in test result correctness and is capable of greatly shortening the test time at the same time.
Owner:江门市崖门新财富环保工业有限公司

Gastrodin injection preparation and preparation method

The invention discloses a gastrodin injection preparation, which comprises the following components by weight: 5-10% of gastrodin, 0.01-0.1% of metal ion complexing agent, 0.6-1.2% of stabilizing agent, 1-2.5% of buffer and the balance of injection water. The invention also provides a preparation method of the gastrodin injection preparation. The gastrodin injection of the present invention can effectively stop the addition of visible foreign matter during a placing process of the gastrodin injection, the defective index of the visible foreign matter in a solution is reduced, the white point and white block precipitation are not generated, the expectation effect can be reached, thereby the treatment effect of gastrodin can be fully performed. The gastrodin injection preparation has the advantages of simple prescription, good stability, high clear degree, safe clinical usage, small adverse reaction and convenient industrial large batch production.
Owner:YANGZHOU ZHONGBAO PHARMA

Process for preparing compound iodine disinfectant

The invention discloses a process for preparing a compound iodine disinfectant. The process comprises the following steps: substituting elemental iodine by adopting povidone-iodine, and dissolving povidone-iodine to form a solution A by using water; dissolving chlorhexidine acetate to form a solution B by using a solvent, mixing the solution A and the solution B, and preparing the compound iodine disinfectant. According to the method, the elemental iodine is substituted by adopting povidone-iodine, and chlorhexidine acetate is dissolved by using a solvent, namely octaphenyl polyoxyethyiene solution or alcoholic solution, so that complexing between the elemental iodine and chlorhexidine acetate is avoided, the content of free iodine and chlorhexidine acetate in the compound iodine disinfectant is ensured, and the solution stability of povidone-iodine and chlorhexidine acetate can be promoted.
Owner:山东安捷高科消毒科技有限公司

Preparation methods and quality control methods of polysaccharide-iron compound and capsule preparation

The invention belongs to the technical field of medicine preparation, and discloses preparation methods and quality control methods of a polysaccharide-iron compound and a capsule preparation. The preparation method comprises the following steps of (1) adding an alkaline substance into ferric salt, reacting, and washing a reactant mixture until the conductivity is less than 5 ms / cm to obtain a ferric hydroxide colloid; and (2) adding oligosaccharide syrup into the ferric hydroxide colloid prepared in the step (1), adjusting the pH value to 11-14, reacting, adjusting the pH value to be less than 7, generating precipitates, performing centrifuging, dissolving the obtained precipitates in a solution with the pH value of 11-14, and performing drying to obtain the polysaccharide-iron compound. The content of free iron in the polysaccharide-iron compound prepared by the method is less than 0.05%, the content of heavy metals is less than 7.5 ppm, the loss of syrup in the reaction process can be greatly reduced, and the cost is saved. The prepared polysaccharide-iron compound is used for preparing the capsule preparation.
Owner:福建呈睿医药科技有限公司

Method for improving homogeneity of cement grinding aid

The invention relates to a method for improving the homogeneity of a cement grinding aid, belonging to the field of cement admixtures. The method mainly comprises the following steps: (I) a water treatment process; and (II) a compounding process for the grinding aid. The water treatment process comprises the following sub-steps: 1, feeding of a purifying agent; 2, sonic treatment; 3, filtration; and 4, thickening treatment of water. Parameters in the above sub-steps are that (1) the weight percentage of the purifying agent is 3 to 10 %; (2) ultrasonic frequency is 20-35 KHZ; (3) the weight percentage of a thickening agent is 2 to 10 %; and (4) time for sonic treatment is 10 to 30 min. The compounding process comprises the following sub-steps: adding water obtained after treatment by the process (I) into a container, dissolving a salt, and carrying out sonic treatment; and successively adding alcohol amine and industrial waste, carrying out stirring for 15 min and then carrying out sonic dispersion. The compounding process utilizes 10% to 20% of alcohol amine, 8% to 17% of the industrial salt, 20% to 30% of the industrial waste and 48% to 60% of water; and ultrasonic time in the process is 10 min to 30 min. The active ingredients of the grinding aid obtained in the invention are greatly improved, and the grinding aid is uniform and stable, does not settle, and has good application prospects.
Owner:北京丰乐宝科技有限公司 +1

Aluminum-magnesium dimeticone chewable tablet and preparation method thereof

The invention discloses an aluminum-magnesium dimeticone chewable tablet. The chewable tablet consists of 30 to 40 percent (by weight) of dimeticone layer and 60 to 70 percent (by weight) of aluminum-magnesium layer, and is characterized in that the dimeticone layer contains a substance which can increase the defoaming capability of dimeticone. The invention also discloses a method for preparing the aluminum-magnesium dimeticone chewable tablet. As the substance which can increase the defoaming capability of the dimeticone is added to the dimeticone layer, the aluminum-magnesium dimeticone chewable tablet provided by the invention not only can effectively enhance the defoaming capability of products, but also can quantitatively determine the defoaming capability.
Owner:Yung Shin Pharm Ind (Kunshan) Co Ltd

Method for preparing trialkyl phosphate

The invention provides a method for preparing trialkyl phosphate, belonging to the chemical engineering field. The method comprises the steps of reacting by virtue of phosphorus oxyhalide and alcoholin an ice-water bath under the protection of inert gas, cooling a system to room temperature by taking ion exchange resin as a catalyst after the reaction, carrying out reduced pressure distillation to remove redundant alcohol and hydrochloric acid, further removing alcohol and acid in the system in one step by virtue of a bubbling method so as to obtain a trialkyl phosphate rough product, and carrying out reduced pressure rectification, so as to obtain a trialkyl phosphate purified product. By utilizing the catalyst, the compexing with trialkyl phosphate is avoided, so that the adverse effects caused by the complexing between a traditional catalyst and a product are effectively avoided, and the yield and purity of the product are increased; by further removing impurities in a bubbling manner, the impurities remained in the reduced pressure distillation process are effectively removed, so that the yield and purity of trialkyl phosphate are further increased; and the total yield of theproduct is more than 95.9%, and the purity of the product is more than 99.8%.
Owner:江苏中丽新材料有限公司

Anti-scaling ball and preparation method thereof

The invention relates to an anti-scaling ball, which comprises, by weight, 110-130 parts of quartz powder, 50-60 parts of zeolite powder, 40-50 parts of sepiolite powder, and 150-200 parts of an adhesive. According to the present invention, by using the technical scheme, quartz powder, zeolite powder and sepiolite powder have a large amount of pores inside, such that Ca<2+> and Mg<2+> in water canbe effectively absorbed after the anti-scaling ball prepared by adhering the quartz powder, the zeolite powder and the sepiolite powder is added to the water purification device; and quartz powder has characteristics of good hardness, wear resistance, stable chemical property and the like, such that the strength and the corrosion resistance of the ball can be effectively enhanced so as to prolongthe service life of the ball.
Owner:宁波清水坊环保科技有限公司

Iohexol injection and preparation method thereof

The invention belongs to the technical field of pharmaceutical preparations and relates to an iohexol injection and a preparation method thereof. The iohexol injection comprises the following constituents in parts by weight: 50-85 parts of iohexol, 0.05-0.25 part of a stabilizer, 0.01-0.05 part of a chelating agent, and 80-100 parts of water for injection, and is prepared by mixing the constituents, and at last using hydrochloric acid with a concentration of 1 mol / L to regulate the pH value to be 7.0-7.4. Compared to the prior art, the iohexol injection adopts the chelating agent with appropriate amount to avoid complexation between the basic remedy and polyvalent metal ions, so as to increase the product stability, ensure that the injection in each batch is undifferentiated in the color, obviously reduce the visible foreign matters and greatly increase the production yield as the product cannot be influenced by the polyvalent metal ions during the preparation process; the preparation duration can be shortened as the injection is prepared with water at 60-65 DEG C; after low-temperature adsorption, the carbon is removed to avoid that the novel visible foreign matter appears as the injection is recrystallized due to cooling after high-temperature adsorption and filling, so as not to cause low yield.
Owner:CISEN PHARMA

A method for improving the homogeneity of cement grinding aid

The invention relates to a method for improving the homogeneity of a cement grinding aid, belonging to the field of cement admixtures. The method mainly comprises the following steps: (I) a water treatment process; and (II) a compounding process for the grinding aid. The water treatment process comprises the following sub-steps: 1, feeding of a purifying agent; 2, sonic treatment; 3, filtration; and 4, thickening treatment of water. Parameters in the above sub-steps are that (1) the weight percentage of the purifying agent is 3 to 10 %; (2) ultrasonic frequency is 20-35 KHZ; (3) the weight percentage of a thickening agent is 2 to 10 %; and (4) time for sonic treatment is 10 to 30 min. The compounding process comprises the following sub-steps: adding water obtained after treatment by the process (I) into a container, dissolving a salt, and carrying out sonic treatment; and successively adding alcohol amine and industrial waste, carrying out stirring for 15 min and then carrying out sonic dispersion. The compounding process utilizes 10% to 20% of alcohol amine, 8% to 17% of the industrial salt, 20% to 30% of the industrial waste and 48% to 60% of water; and ultrasonic time in the process is 10 min to 30 min. The active ingredients of the grinding aid obtained in the invention are greatly improved, and the grinding aid is uniform and stable, does not settle, and has good application prospects.
Owner:北京丰乐宝科技有限公司 +1

Preparation method of purple sweet potato pigment

InactiveCN112442285AStable structureNo photothermal degradationSugar derivativesNatural dyesAcetic acidFreeze-drying
The invention discloses a preparation method of a purple sweet potato pigment. The method comprises the following steps: performing cleaning, airing and cutting. taking an acetic acid aqueous solutionas an extracting agent, carrying out crude extraction according to a solid-liquid ratio of 1: 4, carrying out freeze thawing treatment on the purple sweet potato strips twice, combining pigment crudeextracts, and carrying out vacuum concentration to obtain a pigment concentrated solution; treating the pigment concentrated solution with a graphene oxide dispersion solution, carrying out primary purification, and carrying out centrifugal separation to obtain supernatant; pre-treating and packing adsorption macroporous resin SP70 into a column, and injecting a supernate pigment liquid into a resin layer, wherein the sample loading flow rate is 3.0-3.5 BV / h; washing the resin layer after adsorption saturation with 2BV clear water, wherein an eluent is prepared from 70% ethanol and 0.5% acetic acid, the elution flow rate is 2.0-2.5 BV / h, and the elution volume is 5BV; and collecting eluate, and performing vacuum concentrating and freeze-drying to obtain a purple sweet potato anthocyanin pigment dry product. According to the method, an alcohol solvent is not used, the pigment extraction rate is increased through freeze thawing treatment, impurities such as proteins are removed throughthe adsorption effect of graphene oxide in the purification process, the anthocyanin complexing effect is avoided, the purification effect is improved, and the high-purity purple sweet potato anthocyanin pigment is obtained.
Owner:HUNAN TIANXIANG BIOTECHNOLOGY CO LTD +1
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products