Method for 3D printing of head and brain models with multiple materials at low cost

A 3D printing, multi-material technology, applied in the field of brain medical model manufacturing, can solve the problems of complex operation, increase the cost of medical model production, high price, etc., and achieve the effect of reducing costs

Active Publication Date: 2014-08-20
SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Multi-material and multi-color 3D printers are expensive and complicated to operate, which greatly increases the cost of making medical models

Method used

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  • Method for 3D printing of head and brain models with multiple materials at low cost
  • Method for 3D printing of head and brain models with multiple materials at low cost
  • Method for 3D printing of head and brain models with multiple materials at low cost

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] A method based on low-cost 3D printing of a multi-material head medical model, the specific implementation steps of the method are as follows.

[0056] MR image preprocessing:

[0057] Normalize the MR images by using reorientation and resampling algorithms to obtain images with a size of 256×256×256;

[0058] The non-uniform gray-scale correction algorithm is used to correct the gray-scale of the MR image.

[0059] Segmentation of MR images

[0060] The Marching Cubes algorithm is used to construct the initial three-dimensional surface of brain tissue for brain MR images, and the three-dimensional surface is smoothed by the spatial smoothing force to obtain evenly spaced vertices; then, the brain tissue and non-brain tissue are distinguished by the driving force of the gray scale of the image, and then , the vertices are driven by the brain probability map to move to the real brain tissue boundary, and finally the brain tissue without the skull and skin is obtained. ...

Embodiment 2

[0079] In this embodiment, the steps of MR image preprocessing, MR image segmentation and tissue (organ) three-dimensional model establishment are the same as in Embodiment 1. The difference from Embodiment 1 lies in the 3D printing process. The specific steps are as follows :

[0080] For brain tissue, set the order of printing 90 brain regions one by one in the order of brain regions;

[0081] Slice the 3D mesh model, set the slice thickness, and convert the 3D model into layered cross-sectional data.

[0082] Choose calcium phosphate as the skull printing material, choose medical gelatin to print the soft tissues of the skin and brain, and color suitable colors for different soft tissues;

[0083] Set the layer thickness of 3D printing to 1mm;

[0084] After setting the printing speed, feeding speed and other parameters, the upper computer is connected to the 3D printer for printing: first, print the white matter of a certain brain area, and then print the gray matter of ...

Embodiment 3

[0087] In this embodiment, the steps of MR image preprocessing, MR image segmentation, and establishment of three-dimensional models of tissues (organs) are the same as those in this embodiment. The difference from Embodiments 1 and 2 lies in the 3D printing process. The specific steps are as follows:

[0088] Slice the 3D surface model, set the slice thickness, and convert the 3D model into layered cross-sectional data.

[0089] Choose calcium phosphate as the skull printing material, choose medical gelatin to print the soft tissues of the skin and brain, and color suitable colors for different soft tissues;

[0090] Set the layer thickness of 3D printing to 1mm;

[0091] After setting the printing speed, feeding speed and other parameters, the upper computer is connected to the 3D printer for printing: first, print the white matter as a whole; then, set the filling rate and supports of the gray matter; then, print the outer surface of the gray matter, and the printing thick...

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Abstract

The invention provides a method for 3D printing of head and brain models with multiple materials at low cost. The method includes the steps that an MR image is used, a three-dimensional model is quickly established for brain tissue, different tissue / organs of a brain are printed by the adoption of a 3D printing method in a regional / layered mode, and skull and skin of a left hemisphere and skull and skin of a right hemisphere are printed respectively. Specifically, the method includes the steps of (1) preprocessing the MR image, (2) segmenting and extracting different tissue / organs in the image, (3) establishing the three-dimensional model for the brain tissue / organs and (4) converting the three-dimensional model into cross section data, selecting printing materials and carrying out 3D printing. The three-dimensional model can be precisely established for the brain tissue on the basis of precise segmentation of the MR image, a regional / layered printing mode is used according to distribution characteristics of tissue / organs, a multi-material 3D printing process is converted into a repeated single-material 3D printing process, the requirements for a 3D printer are reduced, and printing cost of the brain model is greatly reduced.

Description

technical field [0001] The invention relates to a low-cost multi-material 3D printing method for a medical brain model, in particular to a manufacturing method for a medical brain model. Background technique [0002] As an innovative technology, 3D printing is based on three-dimensional model data and uses bondable materials such as powdered metal or plastic to construct objects by layer-by-layer printing. Compared with traditional manufacturing methods, 3D printing has obvious cost advantages: no need to design molds, no need to introduce production lines. At the same time, 3D printing is fast in making models, and the cost of making a single object is low. It has been applied in the fields of industrial rapid prototyping, design model manufacturing, and medical prosthetics. In recent years, the rapid development of 3D printing technology has attracted widespread attention and caused great influence. It is a new trend in the development of the manufacturing industry. As t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06T17/00
Inventor 戴亚康周志勇郑健董月芳刘兆邦
Owner SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
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