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Detection device and method and equipment for detecting by using device

A detection device and red blood cell technology, applied in the field of blood analysis devices, can solve problems such as cross-contamination, high cost, complex structure, etc., and achieve the effects of increasing processing capacity, shortening time, and low price

Inactive Publication Date: 2014-09-03
SIEMENS AG
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, this detection device has a complex structure and high cost. Moreover, it takes a long time to clean the microplate, which will reduce the detection efficiency. At the same time, if the microplate is not cleaned thoroughly, cross-contamination may occur, which will affect the accuracy of the test results.

Method used

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  • Detection device and method and equipment for detecting by using device
  • Detection device and method and equipment for detecting by using device
  • Detection device and method and equipment for detecting by using device

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Embodiment Construction

[0033] In the following, various embodiments of the present invention will be described in detail with reference to the accompanying drawings.

[0034] The agglutination phenomenon is produced by particle aggregation. In the presence of antibodies or other substances, antibodies link multiple particles together to form large particle clusters. Observation of antibody agglutination is a common method used to identify specific antigens. The present invention is based on the phenomenon that erythrocytes agglutinate when antibodies are present. The principle of detecting the type of red blood cells is as follows: red blood cells containing only A antigens are type A, those containing only B antigens are type B, those containing both A and B antigens are type AB, and those without A and B antigens are type O. Therefore, the type of red blood cells can be determined based on the presence of antigens and antibodies.

[0035] figure 1A schematic diagram of a detection device 6 acc...

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Abstract

The invention discloses a detection device for detecting red blood cell types and a method and equipment for detecting by using the device. The detection device comprises a reaction-filtering function layer made of a porous material, wherein the reaction-filtering function layer is used for coating red blood cell antibodies with known types; the antibodies and an antigen of red blood cells with a specific type in a sample to be detected are reacted to agglutinate the red blood cells with the specific type; the pore diameter of the porous material of the reaction-filtering function layer is greater than the diameter of the single red blood cell and is less than the size of the agglutinated red blood cell cluster with the specific type so as to intercept the agglutinated red blood cell cluster with the specific type and enable red blood cells which are not agglutinated to penetrate through.

Description

technical field [0001] The present invention relates to an analysis device and method, in particular to a device for analyzing blood and a method for its use. Background technique [0002] Determining the type of red blood cells is not only of great significance in blood transfusion, but also has application value in ethnology, genetics, forensic science, transplant immunity, disease resistance and so on. For example, before blood transfusion, the blood types of the patient (recipient) and the donor (donor) must be checked, and a cross-matching test must be performed. In clinical medicine, in addition to blood transfusion and transplantation immunity, blood type is also required for the examination of specific antibodies for hemolytic disease of the newborn and autoimmune hemolytic anemia. The biological phenomenon of red blood cell agglutination is often used to determine the type of red blood cells. The traditional way is to determine manually. Medical staff or other op...

Claims

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Application Information

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IPC IPC(8): G01N33/80
CPCG01N33/80
Inventor 郁彦彬郭心陈国治
Owner SIEMENS AG
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