Traditional Chinese medicine composition for treating myasthenia gravis and preparation method thereof

A myasthenia gravis and composition technology, applied in the field of traditional Chinese medicine composition, can solve problems such as decreased human immunity, high recurrence rate, and unsatisfactory drug efficacy

Active Publication Date: 2014-10-01
乞国艳
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  • Abstract
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  • Application Information

AI Technical Summary

Problems solved by technology

At present, in the treatment of myasthenia gravis at home and abroad, immunosuppressant therapy is mostly used, and the symptoms are relieved relatively quickly, but the human immunity is weakened, bone marrow is suppressed, endocrine disorders, and the recurrence rate is high; surgery to remove the diseased thymus, the long-term effect is better , but most patients cannot relieve symptoms

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 2

[0077] Example 2 Typical cases of treatment of patients with myasthenia gravis

[0078] The treatment methods all adopt the decoction prepared in Example 1, take it twice, take one dose every day, and take it orally once in the morning and in the evening, and take it orally on an empty stomach for 12 months.

[0079] The clinical remission indicators of patients with myasthenia gravis, 1. Myasthenia symptoms disappear; 2. In patients with myasthenia gravis, the acetylcholine receptor antibody increases in the blood index test, and these indicators will decrease to varying degrees after the patient's condition is relieved. List 1 is as follows:

[0080] serial number Name gender age address diagnosis Pre-AchR-ab After AchR-ab curative effect 1 Fan Moumou male 12 Hebei Province eye muscle type 12.68 0.44 totally relaxed 5 Xiao Moumou male 13 Hunan Province ⅡB 5.17 2.58 totally relaxed 6 Fu Moumou Female 8 Liuz...

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composition for treating myasthenia gravis. The traditional Chinese medicine composition concretely comprises the following raw medicinal materials in parts by weight: 120-180 parts of astragalus membranaceus, 20-50 parts of radix pseudostellariae, 30-60 parts of codonopsis pilosula, 20-30 parts of bighead atractylodes rhizome, 6-10 parts of bupleurum chinense, 6-10 parts of rhizoma cimicifugae, 6-10 parts of angelica sinensis, 20-50 parts of Chinese yam, 6-10 parts of cortex albiziae, 15-40 parts of prepared fleece flower root, 6-20 parts of morinda officinalis, 6-20 parts of mulberry, 3-6 parts of liquorice, 3-6 parts of pericarpium citri reticulatae, 3-6 parts of fructus aurantii, 20-30 parts of caulis spatholobi, 10-20 parts of medlar and 5-12 parts of radix ophiopogonis. The traditional Chinese medicine composition can be used for strengthening the middle warmer and benefiting vital energy, strengthening the spleen and tonifying the kidneys, and soothing the liver and regulating qi as to a patient with myasthenia gravis, and clinical cure is achieved.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating myasthenia gravis and a preparation method thereof. Background technique [0002] Myasthenia gravis (MG) is the main accumulation of acetylcholine receptor (AchR) on the postsynaptic membrane of neuromuscular junction (NMJ), mediated by acetylcholine receptor antibody (AchRAb), cellular immunity (cellular immunity CM ) dependent, complement-involved autoimmune diseases, the pathogenesis of which has not been fully clarified so far. The main clinical manifestation is skeletal muscle weakness. Previous studies believed that the pathogenesis of myasthenia gravis was related to humoral immunity mediated by acetylcholine receptor antibody (AchRAb), and now it is found that cytokines also play a very important role in the occurrence and development of myasthenia gravis, which participates in the production of AchRAb ...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P21/04
Inventor 乞国艳
Owner 乞国艳
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