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A kind of traditional Chinese medicine composition for treating mammary gland hyperplasia and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for the treatment of mammary gland hyperplasia, can solve the problems of long treatment time, slow onset of effect, and insufficient effect

Inactive Publication Date: 2016-03-09
王炜
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, surgery or hormone and receptor blockers are often used for this disease. Although the curative effect is effective, it often leads to disordered hormone metabolism after the disease is cured.
However, some oral medicines are not effective enough, the treatment time is long, and the onset of effect is slow.

Method used

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  • A kind of traditional Chinese medicine composition for treating mammary gland hyperplasia and preparation method thereof
  • A kind of traditional Chinese medicine composition for treating mammary gland hyperplasia and preparation method thereof
  • A kind of traditional Chinese medicine composition for treating mammary gland hyperplasia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] A traditional Chinese medicine granule for treating mammary gland hyperplasia, which is prepared from the following raw materials in parts by weight: 3 parts of Codonopsis pilosula, 5 parts of Radix Astragali, 2 parts of Poria cocos, 2 parts of Radix Paeoniae Alba, 2 parts of Platycodon grandiflorum and 1 part of licorice.

[0050] The preparation method is as follows:

[0051] 1) After mixing the raw materials in the weight ratio, add 2 times the volume of water to extract twice, the first time is 1.5h, the second time is 0.5h, the extracts are combined and filtered, and the filtrate is concentrated to a relative density of 1.1-1.3 Finally, add ethanol to make the alcohol content reach 65% for precipitation, and stand overnight;

[0052] 2) The ethanol solution obtained in step 1) is filtered and the ethanol is recovered, concentrated to a thick paste, and then vacuum-dried into a dry extract;

[0053] 3) the dry extract obtained in step 2) is pulverized into fine pow...

Embodiment 2

[0055] A traditional Chinese medicine pill for treating mammary gland hyperplasia, which is prepared from the following raw materials in parts by weight: 1 part of Codonopsis pilosula, 8 parts of Astragalus membranaceus, 1 part of Poria cocos, 5 parts of Radix Paeoniae Alba, 1 part of Platycodon grandiflorum and 3 parts of licorice.

[0056] The preparation method is as follows:

[0057] 1) After mixing the raw materials in the weight ratio, add 3 times the volume of water to extract twice, the first time is 2 hours, the second time is 1 hour, the extracts are combined and filtered, and the filtrate is concentrated to a relative density of 1.1-1.3. Add ethanol to make the alcohol content reach 75% for precipitation, and let stand overnight;

[0058] 2) The ethanol solution obtained in step 1) is filtered and the ethanol is recovered, concentrated to a thick paste, and then vacuum-dried into a dry extract;

[0059] 3) the dry extract obtained in step 2) is pulverized into fine...

Embodiment 3

[0062] A traditional Chinese medicine capsule for treating mammary gland hyperplasia, which is prepared from the following raw materials in parts by weight: 5 parts of Codonopsis pilosula, 3 parts of Astragalus membranaceus, 5 parts of Poria cocos, 1 part of Radix Paeoniae Alba, 5 parts of Platycodon grandiflorum and 0.5 part of licorice.

[0063] The preparation method is as follows:

[0064] 1) After mixing the raw materials in the weight ratio, add 2.5 times the volume of water to extract twice, the first time is 1.5h, the second time is 0.5h, the extracts are combined and filtered, and the filtrate is concentrated to a relative density of 1.1-1.3 Finally, add ethanol to make the alcohol content reach 60% for precipitation, and stand overnight;

[0065] 2) The ethanol solution obtained in step 1) is filtered and the ethanol is recovered, concentrated to a thick paste, and then vacuum-dried into a dry extract;

[0066] 3) the dry extract obtained in step 2) is pulverized in...

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Abstract

The invention provides a traditional Chinese medicine composition for treating hyperplasia of mammary glands. The traditional Chinese medicine composition is prepared from the following active ingredients in parts by weight: 1-5 parts of codonopsis pilosula, 3-8 parts of astragalus mongholicus, 1-5 parts of poria cocos, 1-5 parts of radix paeoniae alba, 1-5 parts of platycodon grandiflorum and 0.5-3 parts of liquorice. The traditional Chinese medicine composition can obviously reduce E2 and P levels in blood serum of a model rat, increases an E2 / P ratio, reduces nipple height of the model rat, relieves hyperemia and edema of a mammary tissue, reduces acinus number of lobules of the mammary glands, relieves epithelial proliferation of acinus, inhibits acinus secretion, improves the epithelial proliferation of a catheter, and has an effect of treating the hyperplasia of mammary glands. The invention further provides a method for preparing the traditional Chinese medicine composition.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating mammary gland hyperplasia. Background technique [0002] Mammary gland hyperplasia refers to hyperplasia of mammary gland epithelium and fibrous tissue, structural degeneration of breast tissue ducts and lobules, and progressive connective tissue growth. It is the most common breast disease in women. The main causes of mammary gland hyperplasia are the absolute or relative increase of estrogen, as well as adverse mental factors such as excessive mental stress or emotional excitement. Mammary gland hyperplasia is a common and frequently-occurring disease in women of childbearing age, accounting for about 75% of breast diseases, and 2%-5% of patients develop cancer. Hyperplasia of mammary glands belongs to the category of "breast addiction" in traditional Chinese medicine. It is believed that the imbalance of Chon...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61P15/14
Inventor 王炜
Owner 王炜
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