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Glycoprotein enriched composition as a food and/or feed additive and/or as a therapeutic agent

A technology of glycoprotein and composition, applied in the field of glycoprotein enriched composition

Inactive Publication Date: 2014-11-12
VEOS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the misuse and overuse of antibiotics has contributed to the growth of resistant bacteria, causing problems in disease control

Method used

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  • Glycoprotein enriched composition as a food and/or feed additive and/or as a therapeutic agent
  • Glycoprotein enriched composition as a food and/or feed additive and/or as a therapeutic agent
  • Glycoprotein enriched composition as a food and/or feed additive and/or as a therapeutic agent

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Example 1: Production of glycoprotein enriched composition

[0070] A chromatographic technique is used to prepare the glycoprotein enriched composition according to a specific embodiment of the present invention. Figure 3A The composition enriched in lane 2 is shown, where the non-immunoglobulin glycoprotein fraction is increased by 15% compared to the non-enriched plasma fraction in lane 1. Figure 3B Two colored glycoprotein enriched compositions according to specific embodiments of the present invention are shown ( Figure 3A Lane 2). On the one hand, Coomassie Brilliant Blue, which can color all proteins in the solution, is used for staining ( Figure 3B -S1), however, on the other hand, use Glyco staining, such as Glyco-Stain from G Biosciences TM For dyeing, Glyco-Stain TM The glycoprotein in the liquid may be colored, thereby indicating the glycoprotein in the glycoprotein-enriched composition according to the specific embodiment of the present invention.

[0071...

Embodiment 2

[0073] Example 2: The effect of glycoprotein enriched composition

[0074] The glycoprotein-enriched composition according to the present invention was fed to piglets in an early post-weaning in vivo model, where the piglets suffered from enterotoxigenic Escherichia coli. Figure 5 The results of these tests are shown. Early post-weaning piglets fed the glycoprotein-enriched composition showed no deaths and significantly reduced post-weaning diarrhea.

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Abstract

The present invention relates to glycoprotein enriched compositions and their use in the treatment and / or prevention of diseases, more particular gastro-intestinal diseases. The present invention further relates to the use of a glycoprotein enriched composition as a food or feed additive.

Description

Technical field [0001] The present invention relates to glycoprotein-enriched compositions and their use in the treatment and / or prevention of diseases, and more specifically their use in the treatment and / or prevention of gastrointestinal diseases. The present invention also relates to the use of a glycoprotein-enriched composition as a food or feed additive and / or therapeutic composition. Background technique [0002] One of the problems with young children and young animals such as piglets, calves, puppies, and kittens is that they develop diarrhea when they have been weaned. [0003] For example, after weaning, enteropathy in piglets is one of the most common causes of morbidity and death. Enteropathy in industrialized agriculture and animal husbandry causes huge economic losses by reducing growth performance. Reducing post-weaning diarrhea is one of the most important challenges for the pig industry. In commercial practice, different additives have been recommended as a way...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23J1/06A23K1/04A23K1/18A61K35/16A23K10/24A61K35/20A61K35/57
CPCA23K1/184A23K1/1643A61K35/57A61K35/20A23K1/1893A23K1/1631A61K35/16A23J1/06A23K1/1646A23L1/3051A23K20/147A23K20/163A23K20/10A23K50/30A23K50/60A23L33/17A23L33/175A61P1/12A23V2002/00A61K38/1703
Inventor 德克·德拜斯尔贝努瓦·希尼斯
Owner VEOS