The invention discloses soluble plasma protein powder and a preparation method thereof. The soluble plasma protein powder is a mixture prepared by uniformly mixing milk powder and plasma protein powder, wherein the milk powder accounts for 10-40% of the total mass of the soluble plasma protein, pig blood accounts for 40-84% of the total mass of the plasma protein powder, and sugar accounts for 6-20% of the total mass of the plasma protein powder; the plasma protein powder is rich in fragrance, free of blood fishy smell and good in solubility and brewing stability. The preparation method comprises the preparation and operation steps of vacuum blood collection, blood anticoagulation, step-by-step enzymolysis deodorization, membrane concentration, addition of ingredients, high-pressure homogenization, spray drying, and baking and aroma extraction. The soluble plasma protein powder is fragrant, sweet and mellow in taste, has strong milk fragrance and uniform particles, and is easy to dissolve and free of caking and bad fishy smell after being brewed. The whole set of technology is adopted to process the pig blood into the convenient and instant plasma protein powder, so that the development and utilization of blood resources are realized, the utilization value of by-products such as the pig blood is greatly improved, and the market vacancy of the food plasma protein in China is supplemented.