74results about How to "Promote growth and differentiation" patented technology

The invention provides a porous dental implant capable of carrying a drug sustained release system. The porous dental implant comprises an implant body. An external thread connected with alveolar bone is arranged on the outer surface of the implant body. Porous structures are formed among adjacent threads of the external thread. Pores used for storing sustained release drugs are formed in the porous structures. The invention provides a preparing method of the porous dental implant capable of carrying the drug sustained release system. According to the porous dental implant capable of carrying the drug sustained release system and the preparing method thereof, bonding strength is effectively improved, bonding speed is increased, and a porous structure can be achieved easily.

The invention relates to a plant sprouting and branching accelerator and a preparation method thereof. The plant sprouting and branching accelerator is prepared from the following raw materials in percentage by weight: 6 percent of 6-benzylaminopurine, 2 percent of forchlorfenuron, 5 percent of gibberellins, 2 percent of naphthylacetic acid, 2 percent of compound sodium nitrophenolate, 4 percent of brassinolide, 1 percent of indoleacetic acid, 1 percent of Kang polyphenol, 5 percent of seaweed essence, 5 percent of organosilicon penetrant, 0.1 percent of decavitamin, 30 percent of ethanol, 5 percent of glycerinum and the balance of liquid wool grease. An emulsified liquid obtained by emulsifying the components in an emulsifying machine is a branching agent; the concentration of the ethanol is 65 weight percent; the plant sprouting and branching accelerator has the advantages of strong penetrability, clear targeting effect, remarkable pesticide effect, safety, stability and long lasting period, is more beneficial to the sprouting and branching of a plant, can accelerate the sprouting and branching of current-year, annual and two-year buds of the plant, and can accelerate the sprouting and branching of the plant before sprouting to the overall growing season.

The present invention relates to a method for providing an embedded mammalian cell, comprising the steps of providing an alginate sulfate in aqueous solution; reacting the alginate sulfate to form a hydrogel in a gelation step, providing a precursor cell, and embedding the precursor cell in the sulfated alginate hydrogel in an embedding step, thus yielding an sulfated alginate hydrogel embedded cell. The invention further relates to sulfated alginate hydrogels, and cellular grafts comprising a mammalian cell embedded in sulfated alginate hydrogel.

The invention discloses a facility cultivation technique for crop rotation of stropharia rugosoannulata and rice, and belongs to the technical field of edible mushroom cultivation. The facility cultivation technique includes the steps of fermentation of a culture material, construction of a mushroom shed, construction of a ridged bed, seeding, mycelium management and protection, mushroom cultivation and harvesting, and rice planting and harvesting. After the components of the culture material are subjected to composting and fermentation separately, layered laying is adopted, so that nutrient and oxygen supply in the development process of mycelia and fruiting bodies is ensured, the whole fruiting is uniform, the fruiting rate is stable, the total yield is high, the quality is good, the planting cycle is short, and the continuous cropping obstacles can be solved by crop rotation of the stropharia rugosoannulata and rice.

The invention discloses a preparation method of feed with comprehensive nutrition special for loaches. The method comprises the following steps that fish meal, rice flour, broom corn millet, sweet potato powder, potato powder, palm meal, fermented oil tea cake, molasses powder, yeast protein meal and olive meal are mixed and crushed, and peanut shell powder, berberine, cerous citrate and salt areadded for even mixing to obtain a premix; water is added to the premix, steaming and cooling are carried out, allicin, mountain flour, calcium hydrophosphate, isoleucine, lysine and micro-elements areadded for even mixing, granulation and coating are conducted, in the granulation and coating process, an antibacterial coating agent is sprayed, and then the feed with the comprehensive nutrition special for the loaches is obtained. The obtained feed can not only promote fast development of the loaches, make the loaches easily suitable for the breeding environment and improve the survival rate, but also promote differentiation growth of the bone cells and muscle cells of the loaches and improve the immunity of the loaches; meanwhile, the dosage is little, and the nutrition value of the loaches is on a par with that of wide loaches.

The invention provides application of leaf mustard polypeptide to preparation of skin whitening and repair cosmetics. The leaf mustard polypeptide has small molecular weight, can be easily absorbed by the skin and can aim at the problem of pigmentation in the skin damage repair process when being used for preparing the cosmetics; the acceleration of the skin damage repair process is promoted; the skin cell growth differentiation is accelerated; the repair time is shortened; the skin is protected, so that the hyperpigmentation of the skin caused by protection reactivity is relieved.

The invention discloses an external composition for preventing alopecia and promoting hair growth and a preparation method thereof. The method comprises the following raw materials including adenosine, glycyrrhetinic acid, apple polyphenol, baicalin, alcohol and water. The method has the advantages that since hair papilla cells positioned at the central bottoms of hair follicles generate and release proliferation factors, the proliferation and differentiation of hair follicle epithelial stem cells are influenced, and therefore the hair cycle is controlled; the baicalin can maintain the derivatization ability of the hair follicles, the adenosine can improve the proliferation of the hair papilla cells, the glycyrrhetinic acid can prevent the apoptosis of the hair papilla cells, and the applepolyphenol, especially dimers thereof, can promote the differentiation and growth of keratinocytes and protein synthesis. All raw materials of the external composition for preventing alopecia and promoting hair growth are organically combined together, correspondingly the number of the hair follicles can be effectively increased, the vitality of the hair papilla cells in the hair follicles can bemaintained, and the effects of integrally promoting the hair growth and reducing the hair loss are thus achieved.

The invention relates to a special feed additive for meat-purpose quail for resisting cold stress and improving meat quality, and the special feed additive is used for the general problems of frequent enteritis and poor meat quality of quail in northeast China caused by cold stress. Various ingredients carry out synergistic interaction to play the functions of resisting cold stress by procyanidolic ologomer and improving the meat quality, which are attempts and breakthroughs in the feed field. The additive is low in use amount, low in cost, environment-friendly, non-toxic and suitable for large-scale popularization and application.

The invention relates to the technical field of seedling breeding, and particularly relates to a seedling breeding method of passiflora edulis. The method comprises the following steps: (1) base bed treatment, (2) seed pretreatment, (3) germination accelerating treatment, (4) sowing process, and (5) water and fertilizer management. According to the invention, a sowing and seedling breeding methodis adopted, so that the growth and differentiation of seed coat cells can be effectively promoted, the seedling breeding period is shortened, the stress resistance and the adaptability of the passiflora edulis to the environment are improved, and the survival rate is improved. With the adoption of the cultivation method provided by the invention, the survival rate of the passiflora edulis seedlings reaches 96% or above, and the incidence rate of the passiflora edulis seedlings is effectively decreased to 1.6% or below.

The invention discloses resuscitation fluid applied to vitrified cryopreserved mesenchymal stem cells and belongs to the field of resuscitation fluid. The resuscitation fluid applied to the vitrified cryopreserved mesenchymal stem cells comprises 20% of human serum albumin, 0.8-1% of monosaccharide, 0.21-0.23% of a cell growth factor, 1.5% of N-2-hydroxyethylpiperazine-N'-2-ethane-sulphonic acid, 0.8-1.2% of non-essential amino acid, 0.08-0.12% of L-glutamine, 0.03-0.04% of beta-mercaptoethanol and normal saline. The resuscitation fluid applied to the vitrified cryopreserved mesenchymal stem cells has the characteristics of low cell toxicity on the mesenchymal stem cells, low cell toxicity damage and low permeability damage in a vitrified cryopreserved resuscitation process and increased cryopreserved cell resuscitation rate.

The invention discloses a planting method for Tibetan medicine scindapsus aureus, relates to cultivation for a Tibetan medicine, and belongs to the field of biotechnology. The planting method for Tibetan medicine scindapsus aureus is characterized by comprising the following steps of: in spring, performing division propagation, dividing the roots of scindapsus aureus into clusters, and each cluster comprising 3-4 pseudobulbs; planting the clusters in a matrix respectively, selecting the scindapsus aureus with 3-4 leaves and 3-5 roots which are 4-5 cm long; and planting the scindapsus aureus in the matrix, and culturing in the conditions of a humidity of 80% and a temperature of 20 DEG C. The planting method for Tibetan medicine scindapsus aureus has the beneficial effects that lots of scindapsus aureus can be obtained in a short time via small plants for eliminating free radicals, and promoting cell differentiation and the callus differentiation and growth of scindapsus aureus by virtue of plant hormones, thus radically solving the problems of the provenance shortage and short growth time of scindapsus aureus.

Disclosed herein are compositions of CPG15-2 and methods for treating conditions of excessive cell death, such as neurological conditions, using such compositions. Compounds that inhibit the activity of CPG15-2 are also disclosed herein for the treatment of conditions of undesirable cell survival, such as cancer.

The invention discloses a nanometer compound nutrient solution preparation special for broiler chicken and a preparation method thereof. The nanometer compound nutrient solution disclosed by the invention contains 3%-15% of vitamins, 1%-8% of amino acid, 1%-6% of nucleotide, 1%-3% of prebiotics, 6%-30% of surfactant, 2%-12% of cosurfactant, 0.1%-0.5% of anti-bacteria preservative and the balance of purified water. A nanometer technology is adopted for compounding the nutrient substances, such as, vitamins, amino acid, nucleotide and prebiotics into a nanometer emulsion according to the requirement of the broiler chicken for the nutrient substances and the nanometer emulsion is a safe, efficient, stable and quality-controllable compound nutrient nanometer emulsion special for broiler chicken. The compound nutrient solution disclosed by the invention can improve the water solubility, dispersity and absorption rate of the nutrient substances, such as vitamins, and can thoroughly solve the problem of bioavailability of the nutrient substances, such as, lipid-soluble vitamins. A nutrition enriched solution which can be highly absorbed and utilized is supplied for the broiler chicken.

The invention discloses a 3D full-layer skin model, a culture medium for forming the 3D full-layer skin model and a preparation method of the 3D full-layer skin model. The culture medium comprises a protein preparation, and the protein preparation comprises the following components in percentage by mass: 0.1-99% of albumin, 0.1-99% of globulin and 0.1-99% of fibronectin. Serum is not needed in thegas-liquid phase process of preparing the 3D full-thickness skin model by combining the culture medium with pig type I collagen; the prepared 3D full-layer skin model is complete, the activity and the stability are remarkably improved, the application field of the type of model is expanded, and large-scale industrial production of the skin model is achieved.

The invention provides a drug-loaded degradable blood vessel anastomat. The drug-loaded degradable blood vessel anastomat is characterized by comprising main components which are symmetrically arranged; each main component comprises a clamping part, a puncture part and a matching hole, and the puncture parts and the matching holes are symmetrically distributed in the clamping parts respectively; and the puncture parts of the adjacent main parts are connected with the corresponding matching holes in a matching manner. Through controllable degradation, the risk caused by retention of the vascular anastomat is reduced, the strength of the puncture parts can be guaranteed through a pointed iron core, the anastomosis effect is guaranteed, and meanwhile, an iron base body is degradable, the degradation component ferrous ions or iron ions are beneficial to formation of hemoglobin, and blood transportation is facilitated; and growth and differentiation of vascular cells can be promoted throughdrug loading, anastomosis of blood vessels at anastomotic positions is accelerated, generation of spots is reduced, and tissue damage is reduced to the maximum extent.

The invention discloses a titanium alloy bone implant adopting a bio-coating structure and a preparation method of the titanium alloy bone implant. The titanium alloy bone implant comprises a titanium alloy matrix, a porous metal powder coating and a bio-coating, wherein the porous metal powder coating is uniformly distributed on the surface of the titanium alloy matrix and the bio-coating is uniformly distributed on the surface of the porous metal powder coating. The porous metal powder coating and the bio-coating are designed on the implant, multiple pores are formed in the surface of the implant by the aid of the porous metal alloy coating, the bio-coating enters the pores during coating to form closer connection between coatings, the frozen bio-coating forms tiny pores, the bio-coating is made of a resistance-free and easy-to-absorb material, thus, adhesion, proliferation and differentiation of cells are facilitated, regenerated cell tissue can be tightly combined with the porous titanium alloy coating after the bio-coating is completely degraded, the adhesion of regenerated tissue and the implant can be improved, and rejection reactions can be reduced.

The invention relates to the technical field of new materials and relates to a preparation method of a crosslinked chitosan/hyaluronic acid compound porous scaffold. According to the preparation method, natural biological materials such as chitosan and hyaluronic acid are used as raw materials and an organic silane coupling agent KH-560 is used as a crosslinking agent, and the crosslinked chitosan/hyaluronic acid compound porous scaffold which is made of purely natural biological materials and is excellent in mechanical property is prepared adopting a freeze-drying method. The crosslinked chitosan/hyaluronic acid compound porous scaffold prepared by adopting the preparation method has the characteristics of high porosity, high pores strength, large pores diameter and the like, is of an open type pore structure that small pores are contained in large pores, and is suitable for planting cells on the surface of the scaffold, wherein the pore diameter is 100-300 mu m and porosity is more than 90%. Compared with a chitosan scaffold, the crosslinked chitosan/hyaluronic acid compound porous scaffold has the advantages that the mechanical property is better; proliferation and differentiation effect of the cells on the surface of the porous scaffold is better due to the addition of the organic silane coupling agent, and affinity to biological cells is better.