Traditional Chinese medicine preparation for treating toxin type recurrent oral ulcer during external infection and preparation method of traditional Chinese medicine preparation

A traditional Chinese medicine preparation, the technology of exogenous poisoning, applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, pill delivery, etc., can solve the problems of large trauma, immunodeficiency, and high recurrence rate, and achieve the purpose of preventing wound expansion and reducing recurrence. rate, the effect of drug resistance

Inactive Publication Date: 2015-01-14
SHANDONG UNIV QILU HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

(3) Low immune function and immunodeficiency: It has been confirmed that the lymphocytes of RAU patients have lower responses to PHA and concanavalin (ConA) in all stages of ulcers than normal people
However, the drugs used in the treatment of recurrent oral ulcers by Western medicine have relatively large toxic and side effects, and are prone to drug resistance. At present, there is no specific drug; the treatment methods such as burning and laser can be used for patients with obvious pain. Cause a certain amount of mental stress and reduce the patient's quality of life

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0074] In order to solve the above-mentioned technical problems, the present invention also provides a preparation method of the Chinese medicine preparation, the dosage form of the Chinese medicine preparation is an oral liquid, and the preparation method comprises the following steps:

[0075] The first step is to mix honeysuckle, forsythia, Folium Folium Folium and wild chrysanthemum, and add ethanol with an alcohol concentration of 60% to 65% to 3 times to 5 times that of the mixture, and reflux extraction for 2 to 4 times, each time for 2 hours ~3 hours, filter, combine the filtrates, recover ethanol, concentrate to a paste with a relative density of 1.20-1.22 at 70°C, and set aside;

[0076] The second step is to mix the remaining raw materials in proportion, add 3 to 5 times the amount of water relative to the mixture, boil for 2 to 4 hours, filter, and concentrate to a paste with a relative density of 1.21 to 1.22 at 70°C;

[0077] The third step is to mix the paste ob...

Embodiment 1

[0088] Embodiment 1 oral liquid

[0089] 20 parts by weight of honeysuckle, 18 parts by weight of forsythia, 13 parts by weight of Daqingye, 20 parts by weight of wild chrysanthemum, 13 parts by weight of golden buckwheat, 14 parts by weight of wood butterfly, 12 parts by weight of Pulsatilla oleracea, 17 parts by weight of purslane, Shanci 13 parts by weight of mushroom, 18 parts by weight of Senecio, 17 parts by weight of white pomegranate, 14 parts by weight of bezoar, 16 parts by weight of Perrin, 13 parts by weight of Magnolia officinalis, 14 parts by weight of cardamom, 15 parts by weight of citrus aurantium, 12 parts by weight of chicken vine, 13 parts by weight of poria cocos, 12 parts by weight of coix seed, 18 parts by weight of akebia, 13 parts by weight of rush, 12 parts by weight of Cimicifuga, 12 parts by weight of cold water stone, 17 parts by weight of bamboo leaves, 16 parts by weight of lettuce, hanger 6 parts by weight of hemp, 6 parts by weight of horse too...

Embodiment 2

[0097] Example 2 buccal tablet

[0098] 25 parts by weight of honeysuckle, 20 parts by weight of forsythia, 15 parts by weight of Daqingye, 24 parts by weight of wild chrysanthemum, 15 parts by weight of golden buckwheat, 15 parts by weight of wood butterfly, 15 parts by weight of Pulsatilla oleracea, 20 parts by weight of purslane, Shanci 15 parts by weight of mushroom, 20 parts by weight of Senecio, 20 parts by weight of white pomegranate, 15 parts by weight of bezoar, 20 parts by weight of Perrin, 15 parts by weight of Magnolia officinalis, 15 parts by weight of cardamom, 18 parts by weight of citrus aurantium, 15 parts by weight of chicken vine, 15 parts by weight of poria cocos, 15 parts by weight of coix seed, 20 parts by weight of Akebia, 15 parts by weight of rush, 15 parts by weight of Cimicifuga, 14 parts by weight of cold water stone, 20 parts by weight of bamboo leaves, 20 parts by weight of lettuce, hanger 3 parts by weight of hemp, 4 parts by weight of horse toot...

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating toxin type recurrent oral ulcer during external infection. The traditional Chinese medicine preparation comprises honeysuckle, fructus forsythiae, folium isatidis, mother chrysanthemum, wild buckwheat, semen oroxyli, the root of Chinese pulsatilla, purslane, edible tulip, yellowweed, radix ampelopsis, calculus bovis, eupatorium, mangnolia officinalis, amomum kravanh, immature bitter orange, fevervine, Poria cocos, semen coicis, caulis clematidis armandii, junci medulla, rattletop, gypsum rubrum, bamboo leaf, endive, bark of Indian quassiawood, fimbriate calanthe pseudobulb, dindygulen peperomia herb, Roughhaired Holly Root, natant salvinia herb, pterocephalus hookeri heck, manystem stonecrop leaf and phaenosperma globosa. The traditional Chinese medicine preparation has the effects of clearing away heat and toxic materials and invigorating spleen to eliminate dampness and is mainly used for treating toxin syndromes of recurrent oral ulcer during external infection. By utilizing the theory of traditional Chinese medicine, the overall immunity of the organism is regulated on the basis of the overall concept, the targeting property is high during treatment based on syndrome differentiation, the traditional Chinese medicine preparation has the effects of diminishing inflammation and relieving pain, expansion of the wound surface is avoided, and the drug effect is directly accessed to the lesions. Moreover, the traditional Chinese medicine preparation is safe and effective and difficultly generates drug resistance, and the reoccurrence rate is reduced.

Description

[0001] technical field [0002] The invention relates to a medical preparation containing raw materials derived from plants, animals or minerals, in particular to a traditional Chinese medicine preparation for treating recurrent oral ulcers caused by exogenous pathogenic factors and a preparation method thereof. [0003] Background technique [0004] Recurrent oral ulcer, also known as recurrent aphthous ulcer or recurrent aphthous stomatitis, is the most common oral mucosal disease, and its prevalence rate ranks first in oral mucosal diseases. Epidemiological surveys in various countries show that every 5 people At least 1 of them had oral ulcers. The disease is characterized by recurrent ulcers in various parts of the oral mucosa, without other disease signs, with periodic, recurrent, self-limiting characteristics, and obvious burning pain of ulcers. Occurs in poorly keratinized areas such as the lips, tongue, cheeks, and soft palate. [0005] Pathological etiology:...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9064A61P1/02A61K33/06A61K35/413
CPCA61K36/355A61K9/0014A61K9/0053A61K9/0056A61K9/08A61K9/146A61K9/2059A61K33/06A61K35/413A61K36/076A61K36/185A61K36/195A61K36/28A61K36/287A61K36/315A61K36/37A61K36/41A61K36/575A61K36/634A61K36/67A61K36/70A61K36/704A61K36/71A61K36/716A61K36/74A61K36/752A61K36/855A61K36/87A61K36/88A61K36/898A61K36/899A61K36/8994A61K36/9064A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 陈安威刘少华万凤丽
Owner SHANDONG UNIV QILU HOSPITAL
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