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Gossypol removing method for cotton seeds

A technology of dephenolization processing and cottonseed, which is applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, plant raw materials, etc., which can solve the problem of large residual amount of gossypol, difficulty in controlling differences between batches of processed products, and loss of active ingredients in cottonseed and other issues, so as to save energy, solve reproductive toxicity problems, and reduce costs

Inactive Publication Date: 2015-01-21
HETIAN UYGHUR PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The clinical application of cottonseed usually adopts the processing method of frying, which can remove part of free gossypol. The heat and stir-frying techniques are different, which often leads to large differences in the residual amount of gossypol, and the difference between batches of processed products is difficult to control. , and the loss of active ingredients in cottonseed caused by high-temperature stir-frying

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] A kind of dephenol processing method of cottonseed, comprises the steps:

[0016] 1) Take the cottonseed, remove the remaining cottonseed hulls and impurities, after cleaning, soak in deionized water according to the solid-to-liquid ratio of 1:9, continue to soak for 24 hours, and stir once every 6 hours for 30 minutes;

[0017] 2) After the stirring is completed, sonicate for 20 minutes at a frequency of 30 kHz while maintaining slow stirring;

[0018] 3) Take out the cottonseed after ultrasonication, wash 3-6 times with deionized water, dehydrate and dry;

[0019] 4) Circulating steam sterilization for 20 minutes;

[0020] 5) drying and drying at 80°C until the moisture content of the cottonseed is 10%.

Embodiment 2

[0022] A cottonseed dephenolization processing method, the preparation method is the same as in Example 1, the difference is that the solid-to-liquid ratio after net selection is 1:3, continuously soaked for 36 hours, and kept stirring once every 9 hours, the ultrasonic frequency is 10kHz, and the ultrasonic frequency is 10kHz. The time is 10min, and the steam sterilization time is 10min.

Embodiment 3

[0024] A cottonseed dephenolization processing method, the preparation method is the same as in Example 1, the difference is that the solid-to-liquid ratio after net selection is 1:15, continuously soaked for 12 hours, and kept stirring once every 3 hours, the ultrasonic frequency is 50kHz, and the ultrasonic frequency is 50kHz. The time is 30min, and the steam sterilization time is 30min.

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PUM

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Abstract

The invention provides a gossypol removing method for cotton seeds. The method comprises the steps of shelling and cleaning the cotton seeds, putting the cotton seeds into deionized water in a solid-liquid ratio of 1: (3-15), keeping for 12-36khz while stirring, performing ultrasonic treatment for 10-30min under 10-50hz while stirring, washing for 3-6 times, dehydrating, sterilizing for 10-30 minutes with flowing steam, drying at 80 DEG C till the water content is 10%, thus obtaining gossypol removed cotton seeds. By adopting the mild processing method, gossypol is effectively removed, and the defects of high cost, organic solvent residue, insufficient gossypol removal and the like in present general gossypol removing methods are overcome; and the method is simple, saves energy, reduces the cost, and solves the problem of reproductive toxicity of the gossypol included in the cotton seeds.

Description

technical field [0001] The invention belongs to the technical field of medicinal material processing, and in particular relates to a method for processing cottonseeds by removing phenols. Background technique [0002] Cottonseed is a kind of medicinal material, which has the effects of generating dampness and heat, filling semen, fatting the body and promoting lactation, diuretic and anti-inflammatory, dispelling cold and consolidating essence, strengthening the body and aphrodisiac. Thin body and less milk, poor urination, acute and chronic nephritis, cold premature ejaculation, weak impotence, etc. It is also used to enhance libido, remove freckles and brighten. Modern studies believe that cottonseed contains gossypol, also known as gossypol or gossypol, which is a polyphenolic compound formed in cotton plants and exists in various organs of cotton plants, with the highest content in cottonseed kernels. Gossypol exhibits extensive reproductive toxicity to animals. The tox...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K131/00
CPCA61K36/185
Inventor 庞克坚吴志豪郭瑶艾力·阿布都拉
Owner HETIAN UYGHUR PHARMA
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