Monomeric spice Mal-Leu for cigarette as well as preparation method and application of monomeric spice Mal-Leu

A technology for monomers and fragrances, which is applied in the field of preparation of a new type of cigarette monomer fragrance Mal-Leu, achieves the effects of easy availability of raw materials, excellent physical moisturizing effect and high yield

Active Publication Date: 2015-01-28
CHINA TOBACCO HENAN IND
View PDF4 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the humectants widely used in cigarettes in my country mainly include propylene glycol and sorbitol. The purpose of using such humectants is to improve the moisture content of shredded tobacco during processing and the processing resistance of shredded tobacco. The maintenance of moisture content and the improvement of sensory comfort are not ideal

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Monomeric spice Mal-Leu for cigarette as well as preparation method and application of monomeric spice Mal-Leu
  • Monomeric spice Mal-Leu for cigarette as well as preparation method and application of monomeric spice Mal-Leu
  • Monomeric spice Mal-Leu for cigarette as well as preparation method and application of monomeric spice Mal-Leu

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A preparation method for tobacco monomer spice Mal-Leu, comprising the steps of:

[0029] Add 1 gram of maltose, 1.5 mL of dimethylformamide, and 3.0 mL of anhydrous methanol into a three-neck flask equipped with a thermometer and a condenser tube, reflux at 75°C for 23 minutes, then add 0.146 grams of leucine and reflux for another 23 minutes, and finally Add 0.033 gram of strongly acidic ion-exchange resin and 0.339 gram of myricetin for reflux reaction for 1.5h; after the reaction ends, 0.366 gram of the white crystalline target product is obtained through silica gel column chromatography separation and recrystallization; wherein, the eluent used for column chromatography separation is A mixture of n-butanol, glacial acetic acid and water, the volume ratio of the three is 5:2:1, the color developer is ninhydrin ethanol solution; the solvent used for recrystallization is absolute ethanol with a volume ratio of 1:1 mixed solution with anhydrous methanol.

Embodiment 2

[0031] A preparation method for tobacco monomer spice Mal-Leu, comprising the steps of:

[0032] Add 1 gram of maltose, 3.4 mL of dimethylformamide, and 2.1 mL of anhydrous methanol into a three-necked flask equipped with a thermometer and a condenser, and reflux at 82°C for 29 minutes, then add 0.268 grams of leucine and reflux for another 29 minutes, and finally 0.055 g of strong acidic ion exchange resin and 1.016 g of myricetin were added for reflux reaction for 3.5 h; after the reaction, 0.819 g of the target product Mal-Leu in the form of white crystals was obtained through silica gel column chromatography and recrystallization. Wherein, the operation process of column chromatography separation and recrystallization is the same as that of Example 1.

Embodiment 3

[0034] A preparation method for tobacco monomer spice Mal-Leu, comprising the steps of:

[0035] Add 1 gram of maltose, 3.8 mL of propylene glycol and 1.6 mL of anhydrous methanol into a three-necked flask with a thermometer and a condenser tube, reflux at 89°C for 43 minutes, then add 0.364 grams of leucine and reflux for another 43 minutes, and finally add 0.065 grams of strong The acidic ion exchange resin and 1.694 g of myricetin were refluxed for 7.5 hours; after the reaction, 0.605 g of the target product in the form of white crystals was obtained through silica gel column chromatography and recrystallization. Wherein, the operation process of column chromatography separation and recrystallization is the same as that of Example 1.

[0036] (1) Structural characterization of the target product

[0037] Through infrared spectroscopy (IR), high-resolution mass spectrometry (HR-MS), carbon nuclear magnetic resonance spectroscopy ( 13 C-NMR) carry out structural character...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention belongs to the field of essence spices and tobacco processing, and particularly relates to monomeric spice Mal-Leu for cigarette as well as a preparation method and an application of the monomeric spice Mal-Leu. The structural formula of the monomeric spice Mal-Leu for cigarette is as shown in the specification. According to the invention, physical moisture retention property test of the monomeric spice and inherent sensory quality evaluation of finished product cigarette are performed, so that the monomeric spice Mal-Leu can not only obviously improve the physical moisture retention property of the cut tobacco, has the effect of significantly improving the sensory quality of the cigarette, is capable of reducing the stimulation and miscellaneous gas of the cigarette and enhancing the mellow sense of cigarette.

Description

[0001] technical field [0002] The invention belongs to the field of flavors and fragrances and tobacco processing, and in particular relates to a novel monomer fragrance Mal-Leu for cigarettes, a preparation method and an application. [0003] Background technique [0004] As people pay more and more attention to smoking and health problems, while further reducing the amount of tar in cigarettes, the comfort of cigarettes becomes worse, which is mainly reflected in the loss of water dispersion in shredded tobacco, low moisture in mainstream smoke, high irritation, and dry mouth And phlegm etc. At present, the humectants widely used in cigarettes in my country mainly include propylene glycol and sorbitol. The purpose of using such humectants is to improve the moisture content of shredded tobacco during processing and the processing resistance of shredded tobacco. The maintenance of moisture content and the improvement of sensory comfort are not ideal. Contents of the inve...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C07H3/08C07H1/00A24B15/40
Inventor 芦昶彤陈芝飞郝辉李怀奇孙志涛马宇平
Owner CHINA TOBACCO HENAN IND
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap