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Medicament for treating lower respiratory infection and preparation method and applications thereof

A respiratory and pharmaceutical technology, applied in the field of medicine, can solve problems such as complex drug resistance mechanisms and achieve good inhibitory effects

Inactive Publication Date: 2015-02-04
孔杰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The bacterium is naturally resistant to a variety of antibacterial drugs, and the drug resistance mechanism is complex, and it is a multidrug-resistant pathogenic bacterium

Method used

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Examples

Experimental program
Comparison scheme
Effect test

experiment example

[0017] Burkholderia cepacia ATCC 25608 used in the present invention was purchased from Shanghai Beinuo Biotechnology Co., Ltd. The present invention investigates the bacteriostasis by the zone of inhibition method.

[0018] Preparation of drug-containing filter paper discs

[0019] Choose filter paper with strong water absorption and uniform texture, punch it into 6mm discs, pack them in clean and dry test tubes, sterilize at 121°C for 2 hours, and then dry them for later use. Prepare 0.35 g of the extract according to the method described in the example, add 6 liters of water, fully dissolve, and under aseptic operation, soak the prepared paper in the pre-configured drug solution, seal it and soak it in the refrigerator for 1 hour , and then dried in an oven at 37°C, sealed at 4°C and stored for later use.

[0020] Preparation of Broth Medium

[0021] Raw materials: beef extract (3g), peptone (10g), sodium chloride (5g), agar (10g) and distilled water (1000ml). Preparati...

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Abstract

The invention relates to a medicament for treating lower respiratory infection. The medicament contains a Ampelopsis aconitifolia Bunge extract and a pharmaceutically acceptable carrier. The lower respiratory infection is caused by burkholderia cepacia ATCC25608. The medicament disclosed by the invention has a good inhibition effect on burkholderia cepacia ATCC25608 causing lower respiratory infection.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a medicament for treating lower respiratory tract infection and its preparation method and application. Background technique [0002] Burkholderia cepacia is widely distributed in nature and also widely exists in the hospital environment. It is one of the important opportunistic pathogens of nosocomial infection and one of the main pathogens causing lower respiratory tract infection. The bacterium is naturally resistant to a variety of antibacterial drugs, and the drug resistance mechanism is complex, so it is a multidrug resistant pathogen. Therefore, finding drugs that inhibit Burkholderia cepacia is of great significance for the treatment of lower respiratory tract infections. Contents of the invention [0003] The object of the present invention is to provide a medicament for treating lower respiratory tract infection. [0004] In order to achieve the purpose of the present invent...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/87A61P31/04A61P11/00
CPCA61K36/87A61K2236/333A61K2236/51A61K2236/53
Inventor 秦芳
Owner 孔杰
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