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Application of glutamine in treatment of intestinal injury due to endotoxemia

A technology of endotoxemia and glutamine, applied in the field of biomedicine, can solve problems such as decreased intestinal mucosal barrier function, taking advantage of a weak spot, and harming the body

Inactive Publication Date: 2015-03-25
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Probiotics and our gastrointestinal mucosa have built an ecological barrier to resist and fight against various foreign pathogenic microorganisms. The body's resistance will decline, and some originally harmless bacteria may take advantage of the opportunity and cause damage to the body, causing the intestinal mucosal barrier function to decline, especially shock and endotoxemia

Method used

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Examples

Experimental program
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Effect test

example 1

[0013] Clinically, there are many reasons for the decline of intestinal mucosal barrier function, especially shock and endotoxemia. In a pathological state, intestinal barrier function damage is related to the low glutamine level of the body. Glutamine can effectively reduce intestinal damage caused by various pathogenic factors and has a protective effect. Glutamine is mainly used as a method to treat intestinal damage caused by endotoxin due to various reasons. Oral glutamine 1g / d.

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PUM

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Abstract

The invention belongs to the technical field of biomedicine, and particularly relates to method for treating intestinal injury due to endotoxemia by using glutamine. Glutamine is mainly used for treating intestinal mucosal injury due to endotoxemia caused by various reasons, is capable of increasing the height of intestinal villus, reducing intestine permeability, enhancing intestinal immunity, preventing bacterial translocation, maintaining intestinal mucosal barrier and effectively relieving intestinal injury caused by various pathogenic factors, has effects of protecting intestinal mucosa, protecting intestinal tissue structures and keeping intestinal functions, and provides support to enteral nutrition after intestinal injury due to endotoxemia.

Description

technical field [0001] The invention discloses a treatment method for intestinal damage caused by endotoxemia caused by glutamine, which belongs to the field of biomedicine. Background technique [0002] As an immune organ, the intestinal tract acts as a barrier against bacteria and endotoxins. Under normal circumstances, the vast majority of bacteria in the gastrointestinal tract are beneficial to the human body. We call them "probiotics", which can help us digest lactose, degrade and excrete excess cholesterol; provide our body with vitamins B1, B2, B6, B12, as well as pantothenic acid, niacin, vitamin K, etc.; stimulate the development of our immune organs, and promote the continuous evolution and improvement of their functions, which is beneficial to human health. Probiotics and our gastrointestinal mucosa have built an ecological barrier to resist and fight against various foreign pathogenic microorganisms. The body's resistance will decline, and some originally harml...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/198A61P1/00
CPCA61K31/198
Inventor 范红斌庞庆丰陈俊良杜斌
Owner JIANGNAN UNIV
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