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Ginger extract with activity of assisting in lowering blood sugar level and preparation method of ginger extract

A kind of ginger extract and extract technology, applied in the field of ginger extract with auxiliary hypoglycemic activity and preparation field

Inactive Publication Date: 2015-03-25
BOHAI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are few reports on the auxiliary hypoglycemic activity of ginger extract

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1, after cleaning and drying the ginger slices, dry and pulverize them, cross a 60-mesh sieve, weigh 5g of ginger powder, add deionized water according to the solid-to-liquid ratio of 20:1, and extract for 2h at 40°C. After the extraction, Centrifuge at 4000r / min, take the supernatant, extract the filter residue twice according to the above parameters, combine the filtrates, and dry to dryness under reduced pressure to obtain the ginger extract; then use the ginger extract as a raw material to measure its α - The half-inhibitory concentration of glucosidase is 2.51 mg / mL, and the half-inhibitory concentration of alpha-amylase is 3.86 mg / mL.

Embodiment 2

[0024] Embodiment 2, after cleaning and drying the ginger slices, dry and pulverize them, pass through a 60-mesh sieve, weigh 5g of ginger powder, add deionized water according to the solid-to-liquid ratio of 30:1, and extract for 3 hours at 50°C. After extraction, Centrifuge at 4000r / min, take the supernatant, extract the filter residue twice according to the above parameters, combine the filtrates, and dry to dryness under reduced pressure to obtain the ginger extract; then use the ginger extract as a raw material to measure its α - The half-inhibitory concentration of glucosidase is 2.01 mg / mL, and the half-inhibitory concentration of alpha-amylase is 3.52 mg / mL.

Embodiment 3

[0025] Embodiment 3, after cleaning and drying the ginger slices, dry and pulverize them, pass through a 60-mesh sieve, weigh 5g of ginger powder, add deionized water according to the solid-to-liquid ratio of 40:1, and extract at 60°C for 4h. After the extraction, Centrifuge at 4000r / min, take the supernatant, extract the filter residue twice according to the above parameters, combine the filtrates, and dry to dryness under reduced pressure to obtain the ginger extract; then use the ginger extract as a raw material to measure its α - The half-inhibitory concentration of glucosidase is 1.65 mg / mL, and the half-inhibitory concentration of alpha-amylase is 3.15 mg / mL.

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PUM

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Abstract

The invention belongs to the technical field of ginger deep processing and biotechnology and provides ginger extract with the activity of assisting in lowering a blood sugar level and a preparation method of the ginger extract. The ginger extract provided by the invention is prepared by extracting ginger edible parts with de-ionized water. The specific method comprises the following steps: extracting for 2-4 hours at the temperature of 40-60 DEG C in a liquid-solid ratio ranging from (20:1) to (40:1), and centrifuging; taking liquid supernatant; and decompressing and drying to obtain the ginger extract. The content of total phenol compounds in the ginger extract is more than or equal to 0.55mg / g, the content of general flavone is more than or equal to 0.32mg / g and the content of polysaccharide is more than or equal to 150.0mg / g; and activity determination shows that the ginger extract has the activity of assisting in lowering the blood sugar level.

Description

technical field [0001] The invention belongs to the field of deep processing and biotechnology of ginger, and specifically relates to a ginger extract capable of inhibiting both alpha-glucosidase activity and alpha-amylase activity and having auxiliary hypoglycemic activity and a preparation method. Background technique [0002] Diabetes mellitus is a serious endocrine and metabolic disorder caused by insulin deficiency. Nowadays, the prevalence of diabetes is increasing day by day, and the number of people is increasing year by year. Diabetes has become one of the most challenging diseases in the world today. Diet, eating, and urination are the main symptoms of diabetes, which has added a huge medical and economic burden to the society. and staff pressure. Scientific research has proved that there are many biological enzymes in the human body, such as α-glucosidase and aldose reductase, which are involved in regulating blood sugar levels. Oral hypoglycemic effect can be a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P3/10
CPCA61K36/9068A61K2236/30A61K2236/39A61K2236/51
Inventor 赵文竹于志鹏励建荣
Owner BOHAI UNIV