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A kind of medicine for external application capable of regulating blood pressure, lowering blood fat and softening blood vessels and preparation method thereof

A technology for softening blood vessels and externally used drugs, applied in the field of SWIT brand blood regulating bubble legs granules), can solve problems such as gastric irritation, influence on liver and kidney functions, etc., to improve safety, improve the quality of extracts, and improve therapeutic efficacy. exact effect

Inactive Publication Date: 2018-10-26
通化斯威药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] In the prior art, most of the medicines used for the treatment of blood pressure instability caused by primary and secondary hypertension are oral preparations. Excessive use not only affects liver and kidney functions, but also has great irritation to the stomach.
It has not been reported that external application of Chinese herbal medicines and appropriate application methods can also help regulate blood pressure

Method used

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  • A kind of medicine for external application capable of regulating blood pressure, lowering blood fat and softening blood vessels and preparation method thereof
  • A kind of medicine for external application capable of regulating blood pressure, lowering blood fat and softening blood vessels and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A medicine for external use capable of regulating blood pressure, lowering blood fat, and softening blood vessels, which is made into granules of raw materials in the following parts by weight: 15 parts of Digupi, 8 parts of Prunella vulgaris, 8 parts of Danshen, 8 parts of Semen Cassiae, and 10 parts of Rehmannia glutinosa , 10 parts of Pueraria lobata, 10 parts of Uruguay, 10 parts of Astragalus, 4 parts of Angelica, 4 parts of Uncaria, 4 parts of Eucommia, 4 parts of Rhubarb, and 5 parts of Suanzaoren.

[0030] Preparation method: Cut Digupi, Danshen, Dihuang, Pueraria Radix, and Astragalus into 10-15mm segments, mix with Prunella vulgaris, Cassia, Silico, Angelica, Uncaria, Eucommia, Rhubarb, and Suanzaoren, and heat and reflux In the extraction tank, add 5 times the amount of water to soak for 1 hour, heat and reflux for extraction for 5 hours, concentrate to a specific gravity of 1.15-1.20, dry at 80°C, crush into fine powder, and make granules. After passing the i...

Embodiment 2

[0032] A medicine for external use capable of regulating blood pressure, lowering blood fat, and softening blood vessels, which is made into granules of raw materials in the following parts by weight: Digupi 9 parts, Prunella vulgaris 12 parts, Salvia miltiorrhiza 12 parts, Cassia seed 12 parts, Rehmannia glutinosa 7 parts , 7 parts of kudzu root, 7 parts of Uruguay, 7 parts of astragalus, 6 parts of angelica, 6 parts of uncaria, 6 parts of Eucommia, 6 parts of rhubarb, and 3 parts of jujube seed.

[0033] Preparation method: Cut Digupi, Danshen, Dihuang, Pueraria Radix, and Astragalus into 10-15mm segments, mix with Prunella vulgaris, Cassia, Silico, Angelica, Uncaria, Eucommia, Rhubarb, and Suanzaoren, and heat and reflux In the extraction tank, add 5 times the amount of water to soak for 1 hour, heat and reflux for extraction for 5 hours, concentrate to a specific gravity of 1.15-1.20, dry at 80°C, crush into fine powder, and make granules. After passing the inspection, use ...

experiment example 1

[0035] Process selection orthogonal experiment results are:

[0036] factor level table

[0037]

[0038] Orthogonal experiment design table and results

[0039]

[0040]The optimal experimental conditions selected from the above test results are: the extraction time of the medicinal materials is 5 hours, and the amount of the solvent is 5 times that of the medicinal materials.

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PUM

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Abstract

The invention relates to an external used medicine or a health care product, in particular to a preparation method of an external used medicine capable of regulating blood pressure, reducing blood fat and softening blood vessels. The preparation method of the external used medicine capable of regulating the blood pressure, reducing the blood fat and softening the blood vessels includes: cutting cortex lycii radicis, red sage roots, rehmannia, roots of kudzu vine and astragalus into segments of 10-15mm in length, mixing the segments of the cortex lycii radicis, the red sage roots, the rehmannia, the roots of the kudzu vine and the astragalus with selfheal, cassia seeds, herba siegesbeckiae, Chinese angelica, uncaria, Eucommia ulmoides, rheum officinale and spina date seeds so as to obtain a mixture, placing the mixture in a heat reflux extraction tank, adding a large amount of water, which is 5 times of the amount of all the above medicine material, so as to steeping the mixture for one hour, performing heat reflux extraction on the mixture for 5 hours, concentrating the mixture until the specific gravity of the mixture is 1.15-1.20, drying the mixture under temperature of 80 degree centigrade, smashing the mixture into fine powder, manufacturing the fine powder into particles, using a pharmaceutical packaging composite film to pack the particles after the particles pass inspection, and bagging 20g of the particles in each bag. The external used medicine capable of regulating the blood pressure, reducing the blood fat and softening the blood vessels has a healthcare function, assists in regulating the blood pressure, and is suitable for a crowd of people which are unsteady in blood pressure due to primary and secondary hypertension.

Description

technical field [0001] The present invention relates to a medicine for external use, a health product and a preparation method thereof, in particular to a medicine for external use capable of regulating blood pressure, lowering blood fat and softening blood vessels and a preparation method thereof (commodity name: Sway Brand Xuetiao Soaked Leg Granules). Background technique [0002] In the prior art, most of the medicines for the treatment of blood pressure instability caused by primary and secondary hypertension are oral preparations. Excessive use not only affects the liver and kidney functions, but also has great irritation to the stomach. It has not been reported that external application of Chinese herbal medicines and appropriate application methods can also help regulate blood pressure. Contents of the invention [0003] The object of the present invention is to provide a medicine for external use capable of regulating blood pressure, lowering blood fat and softeni...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/815A61P3/06A61P9/12
CPCA61K9/0014A61K36/232A61K36/28A61K36/46A61K36/481A61K36/482A61K36/488A61K36/536A61K36/537A61K36/708A61K36/725A61K36/74A61K36/804A61K36/815A61K2236/331A61K2300/00
Inventor 杜明珠
Owner 通化斯威药业股份有限公司
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