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Longan pericarp extract as well as extracting method, composition and application thereof

A technology of fruit peel extract and longan, applied in the field of longan peel extract and its extraction, to achieve the effect of easy access and rich variety

Inactive Publication Date: 2015-04-29
NORTHEASTERN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The effect of longan skin extract on blood sugar has not been reported

Method used

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  • Longan pericarp extract as well as extracting method, composition and application thereof
  • Longan pericarp extract as well as extracting method, composition and application thereof
  • Longan pericarp extract as well as extracting method, composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Extraction process of longan skin extract

[0033] 1.1 Take dried longan pericarp, crush it into powder, add 70% ethanol water solution to 30 times of the raw material, soak at room temperature for 1 hour, and extract 3 times.

[0034] 1.2 The extracts were combined, concentrated under reduced pressure to dryness to obtain a crude extract.

[0035] 1.3 Take the macroporous resin XAD-16 whose weight is 40 times the weight of the crude extract and pack it into a column, first elute with water whose volume is 15 times the volume of the resin, and then use 95% ethanol whose volume is 20 times the volume of the resin to elute, The eluate was collected and concentrated to dryness under reduced pressure to obtain the extract.

Embodiment 2

[0037] Extraction process of longan skin extract

[0038] 1.1 Take dried longan pericarp, grind it into powder, add 95% ethanol as 20 times of the raw material, soak at room temperature for 1 hour, and extract 3 times.

[0039] 1.2 Filter the extract and concentrate under reduced pressure to dryness to obtain a crude extract.

[0040]1.3 Take the macroporous resin XAD-16 whose weight is 30 times the weight of the crude extract and pack it into a column, first elute with water whose volume is 15 times the volume of the resin, and then use 95% ethanol whose volume is 20 times the volume of the resin to elute, The eluate was collected and concentrated to dryness under reduced pressure to obtain the extract.

Embodiment 3

[0042] Extraction process of longan skin extract

[0043] 1.1 Take dried longan pericarp, grind it into powder, add 30% ethanol as 30 times of the raw material, warm soak at 60°C for 1 hour, and extract 3 times.

[0044] 1.2 Filter the extract and concentrate to dryness under reduced pressure to obtain a crude extract.

[0045] 1.3 Take the macroporous resin XAD-16 whose weight is 25 times the weight of the crude extract and pack it into the column, first elute with water whose volume is 20 times the resin volume, and then use 95% ethanol whose volume is 50 times the resin volume to elute, The eluate was collected and concentrated to dryness under reduced pressure to obtain the extract.

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Abstract

The invention provides longan pericarp extract as well as an extracting method, a composition and application thereof. The extracting method comprises the following steps: extracting longan pericarp through an alcohol aqueous solution to obtain an extracting solution; concentrating the extracting solution to obtain crude extract; and performing column chromatography on the crude extract to obtain the longan pericarp extract, wherein the extracting is preferably performed by 1-3 times; based on the dried longan pericarp, weight of the alcohol aqueous solution used for every extracting is preferably 10-30 times the weight of the raw materials; the volume concentration of the alcohol aqueous solution is preferably 20-95%. The longan pericarp extract is firstly found to have relatively good blood sugar reducing activity and have advantages that the chemical components are remarkably different from those of kernel, the active substances are relatively rich, the raw materials are easily available, and the like.

Description

technical field [0001] The invention relates to extracting an extract capable of lowering blood sugar from longan skin, a preparation method of the extract, and the extract as a medicine and health care for the treatment and prevention of hyperglycemia, diabetes and its complications and other related metabolic diseases. product application. Specifically, it relates to a longan peel extract and its extraction method, composition and application. Background technique [0002] Diabetes is a chronic progressive metabolic disease. In 2013, the number of patients diagnosed worldwide reached 400 million, and the incidence rate increased year by year (Shi & Hu, 2014). Hyperglycemia is a typical feature of clinical manifestations of diabetes. Hyperglycemia in long-term patients leads to a series of complications, including cardiovascular disease, diabetic nephropathy, diabetic eye disease, and neurological disease (Gao, Xu, Wang, & Hochstetter, 2013). [0003] At present, contro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/77A23L1/29A61P3/10A61K131/00A23L33/00
Inventor 黄学石李莉娅许家林韩力王占友
Owner NORTHEASTERN UNIV
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