Vector transcranial magnetic stimulation method on basis of trend of nerve fibers

A transcranial magnetic stimulation and nerve fiber technology, applied in the fields of magnetic therapy, electrotherapy, treatment, etc., can solve the problems of difficult to accurately evaluate the stimulation effect, low resolution of the stimulation area, and difficult to accurately stimulate the nerve fibers.

Inactive Publication Date: 2015-07-01
INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
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AI Technical Summary

Problems solved by technology

[0006] 1. The resolution of the stimulation area is too low. Nerve stimulation is mainly aimed at the stimulation of nerve axons, and the purpose of nerve conduction is achieved by changing the internal and external potential of the axons, while the resolution of the stimulation position of the stimulator positioned at the cortical level is too low
[0007] 2. The stimulation effect is difficult to accurately evaluate
The calculation of the induced electric field strength is related to the discharge current of the coil and the positional relationship between the coil and the brain stimulation area. It is difficult to achieve precise magnetic stimulation based on the direction of nerve fibers in the existing technology

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  • Vector transcranial magnetic stimulation method on basis of trend of nerve fibers
  • Vector transcranial magnetic stimulation method on basis of trend of nerve fibers
  • Vector transcranial magnetic stimulation method on basis of trend of nerve fibers

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Embodiment Construction

[0047] The vector transcranial magnetic stimulation method based on the direction of nerve fibers of the present invention will be described in detail below with reference to the embodiments and the accompanying drawings.

[0048] like figure 1 As shown, the vector transcranial magnetic stimulation method based on nerve fiber direction of the present invention comprises the following steps:

[0049] 1) Determine the stimulation direction of the target brain nerve fibers;

[0050] For the stimulation direction of the brain nerve fibers, first obtain the human brain diffusion tensor imaging (diffusion tensor imaging, DTI) data, and obtain the target nerve fibers according to the fiber tracing technology; extract a certain number of spatial voxels on the target nerve fibers point, and linearly fit the space voxel points to obtain the initial fitting vector direction; increase the same number of pixel points to fit again, and calculate the fitted vector direction after each fitti...

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Abstract

The invention discloses a vector transcranial magnetic stimulation method on the basis of trend of nerve fibers. The vector transcranial magnetic stimulation method includes determining stimulation directions of target cranial nerve fibers; overlaying positions of points with the most intensive stimulation generated by coils and the positions of target stimulation points; enabling the directions of most intensive magnetic fields generated by the coils to coincide with target stimulation directions; respectively computing induced electric field vectors and induced current vectors of prime spots of various space bodies of cranial nerve fibers on the basis of the trend of the target cranial nerve fibers. The vector transcranial magnetic stimulation method has the advantages that the nerve stimulation spatial resolution can be improved, the target stimulation nerves can be positioned by users according to experimental requirements, the coils are matched with the positions of the nerves, and accordingly predictable stimulation results can be realized; the induced electric field vectors and the induced current vectors on the basis of positional relations between the coils and the nerve fibers can be estimated, and the induced electric field vectors and the induced current vectors on the basis of the trend of the target nerve fibers can be computed by the users according to positional relations between the coils and cerebral stimulation regions.

Description

technical field [0001] The invention relates to a transcranial magnetic stimulation method. In particular, it relates to a vector transcranial magnetic stimulation method based on the orientation of nerve fibers. Background technique [0002] Transcranial Magnetic Stimulation (TMS) is a new stimulation technology developed in the past 30 years. Magnetic stimulation is non-invasive, easy to operate, and has the advantages of better electrical safety than electrical stimulation technology. And other fields, especially in the treatment of depression, obsessive-compulsive disorder, Parkinson's disease, epilepsy and post-traumatic stress disorder, etc., have good application prospects and become a research hotspot in recent years. [0003] The transcranial magnetic stimulation device discharges the inductive coil through a high-power capacitor, and generates a changing current on the coil for a short time. According to the laws of electromagnetic induction, a changing current p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N2/04
Inventor 殷涛李松刘志朋赵琛
Owner INST OF BIOMEDICAL ENG CHINESE ACAD OF MEDICAL SCI
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