Combined drug for treatment of cow hoof disease and preparation method thereof

Abstract

The invention relates to a combined drug for treatment of cow hoof disease. The drug comprises ethylenediamine dihydroiodide and copper sulfate that are mixed in a mass ratio of 1:2-2:3. The ethylenediamine dihydroiodide can react with copper sulfate to release free elementary iodine, free state iodine atom has ultrastrong oxidation, and can enable protein denaturation and destroy the cell membrane structure of pathogens, thereby achieving the purposes of preventing infection and treating cow hoof disease. The drug provided by the invention has the advantages of short treatment cycle, high cure rate and no pollution to the environment and milk production.

Description

technical field [0001] The invention relates to the field of animal husbandry and veterinary disease treatment, in particular to a combined medicine for treating bovine hoof disease. Background technique [0002] In dairy farming, hoof disease, mastitis and reproductive disorders are the three major diseases that cause dairy cows to be eliminated. 90% of lameness in dairy cows is caused by hoof disease. Therefore, hoof disease is a common disease in dairy cows. The main reason is the imbalance of calcium and phosphorus in the diet or the lack of trace elements, which leads to loose horny hooves, coupled with the harsh environment of the pen, the hooves are often soaked in feces, urine, and mud, and the horny hooves soften and become diseased. In addition, hard objects such as stones, iron filings, grass and wood chips, glass slag, etc., will stab the soft tissue of the hoof and cause infection and inflammation. After the cow suffers from lameness, the appetite decreases, th...

AI Technical Summary

Problems solved by technology

The main function of the hoof bath is to prevent hoof disease in cattle, but it is poorly targeted for the cattle that have already developed the disease. Therefore, the therapeutic effect is not obvious, and there are often a lot of debris such as feces and urine in the hoof bath to pollute the medicine, resulting in waste of medicine. and the risk of polluting the environment

For hoof disease cows, only take 0.1% potassium permanganate and copper sulfate solution to wash, bathe the hooves or sprinkle potassium permanganate powder on the wound. The pain reaction of the cow is obvious. The whole process takes 20-30 minutes, with an average of 5 minutes. -Change the dressing in 7 days, generally need to change 2-3 times, still lame within 7-10 days, the cure rate of sick cows is only 50-60% in 15-20 days, therefore, the treatment cycle is long and the curative effect is not ideal

[0004] In addition, the Chinese patent document titled "1% Feed Additive for Preventing Lame Disease in High-yielding Dairy Cows and Its Preparation and Application" (Application No.: 201210574027.2) discloses a feed additive that reduces the occurrence of lame disease, although it can prevent dairy cows from hoof disease, but the iodine source used is elemental iodine, and most of the copper source used is copper sulfate pentahydrate, its bioavailability is not high, which is not conducive to the body's absorption and utilization, and most of it will be excreted into the environment with feces and urine , its heavy metal copper will pollute the ecological environment

Images