Eye fundus image optical cup automatic segmentation method based on improved PDE image repairing

A fundus image and automatic segmentation technology, which is applied in the field of medical image processing, can solve the problems of the segmentation result staying in the preliminary stage, the segmentation result is not accurate, and the edge of the optic cup is not clear, so as to reduce manual intervention, ensure accuracy, and ensure The effect of split speed

Inactive Publication Date: 2015-08-12
BEIJING UNIV OF TECH
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Problems solved by technology

[0004] However, the current methods for automatic segmentation of the optic cup are still very limited. In the process of segmentation of the optic cup, the current method is easily affected by the

Method used

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  • Eye fundus image optical cup automatic segmentation method based on improved PDE image repairing
  • Eye fundus image optical cup automatic segmentation method based on improved PDE image repairing
  • Eye fundus image optical cup automatic segmentation method based on improved PDE image repairing

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Embodiment Construction

[0029] Step 1, read the original image, and normalize the image size to 1440*960 pixels, such as figure 2 .

[0030] Step 2, perform channel selection on the original image, and select the most prominent green channel image U in the target area G Segmentation of the optic cup, such as image 3 .

[0031] Step 3, the image is enhanced through the principle of morphology. This method uses the image top hat and bottom hat transformation to enhance the image:

[0032] T hat (U G ) = U G -(U G οSE)

[0033] B hat (U G )=(U G ·SE)-U G

[0034] u CE =(U G +T hat (U G ))-B hat (U G )

[0035] In the formula: the symbol "ο" indicates that the image is opened, and the symbol "·" indicates that the image is closed. SE is a structural element, and a circular structural element of 5*5 is taken. T hat (U G ) is the image after top-hat transformation, B hat (U G ) is the image after bottom hat transformation, U CE is the image after contrast enhancement, and the im...

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Abstract

The invention discloses an eye fundus image optical cup automatic segmentation method based on improved PDE image repairing. The method is carried out with following steps: reading and normalizing an original image; selecting channels for the original image; enhancing the image based on a morphological principle; positioning blood vessels based on an image subtraction; filling and repairing blood vessel areas by the use of an improved BSCB model; performing median filtering and noise reduction for the image and highlighting object areas through gamma transformation; and preliminarily obtaining an optical cup contour through a level set algorithm under a condition that the mass center of the brightest pixel point set on the image serves as an initial seed point. According to the invention, the image in which the blood vessels are filled and repaired eliminate the influence on optical cup segmentation by the blood vessel areas to a certain extent; the accuracy of optical disk segmentation is improved; the seed point is automatically selected as the contour of an optical cup is obtained through the level set algorithm; and manual intervention in a conventional semi-automatic method is reduced.

Description

technical field [0001] The invention belongs to the field of medical image processing, relates to an improved partial differential equation (PDE)-based BSCB image repair model, and realizes the automatic segmentation of the optic cup of the fundus image. Background technique [0002] Fundus and optic nerve tissue lesions caused by various reasons are called fundus optic nerve diseases (such as glaucoma, diabetic retinopathy, etc.), and these diseases all have the risk of blindness. The incidence of such diseases is very high worldwide, and it is showing an upward trend, and the change of the cup size in the fundus image has important guiding significance for the early diagnosis and treatment of glaucoma and other lesions. Segmentation is a key technique for computer-aided diagnosis of eye-related lesions. [0003] At present, there are many researches on the automatic segmentation of the optic cup in fundus images. These methods are generally divided into three types: meth...

Claims

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Application Information

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IPC IPC(8): G06T7/00
CPCG06T7/12G06T2207/10004G06T2207/20032G06T2207/20192G06T2207/30041
Inventor 杨春兰段彦华刘冰
Owner BEIJING UNIV OF TECH
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