Eureka AIR delivers breakthrough ideas for toughest innovation challenges, trusted by R&D personnel around the world.

Production method of swine mycoplasmal pneumonia inactivated vaccine

A technology of inactivated vaccines and Mycoplasma suis, which is applied in the direction of bacterial antigen components and antibacterial drugs, and can solve the problems of late start of inactivated vaccines

Active Publication Date: 2015-09-30
北京中海生物科技有限公司 +2
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

my country is in a leading position in the development of live vaccines, but it started relatively late in the development of inactivated vaccines

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Production method of swine mycoplasmal pneumonia inactivated vaccine
  • Production method of swine mycoplasmal pneumonia inactivated vaccine
  • Production method of swine mycoplasmal pneumonia inactivated vaccine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0018] This strain is prepared by inoculating Lps-5 medium with S strain of Mycoplasma hyopneumoniae, harvesting the culture, adding an appropriate amount of adjuvant, and emulsifying. For the prevention of swine mycoplasma pneumonia (commonly known as swine panting disease).

[0019] 1 strain

[0020] (1) The strain used to manufacture this product is Mycoplasma hyopneumoniae (Mycoplasma hyopneumoniae) S strain, which was isolated and identified by Beijing Zhonghai Biotechnology Co., Ltd.; Preserved at the General Microbiology Center of China Committee for the Collection of Microbial Cultures, No. 3, No. 1, Beichen West Road, Chaoyang District, Beijing, Institute of Microbiology, Chinese Academy of Sciences, and the preservation number is CGMCC No.10095. The bacterial species used for efficacy testing is Mycoplasma hyopneumoniae JN strain, provided by China Veterinary Drug Control Institute.

[0021] (2) The strain standard for the production of Mycoplasma hyopneumoniae S s...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a production method of a swine mycoplasmal pneumonia inactivated vaccine. The swine mycoplasmal pneumonia inactivated vaccine disclosed by the invention is produced by successfully separating a mycoplasma hyopneumoniae S strain having good immunogenicity and used as a production bacterial strain, and researching a proper cultural method, an inactivating process and a proper immunologic adjuvant by using a high-efficiency culture medium. After being used for immunized piglets, the inactivated vaccine produced by the invention can obtain good immune protective efficacy.

Description

technical field [0001] The invention relates to an inactivated vaccine for preventing infectious diseases of pigs, and the patent belongs to the technical field of veterinary biological products. Background technique [0002] Mycoplasma pneumoniae of swine (MPS), also known as porcine endemic pneumonia (Enzootic pneumoniae of Swine, EPS), commonly known as swine panting disease, is a chronic contact respiratory disease caused by Mycoplasma hyopneumoniae Infectious disease, the main symptoms are cough and wheezing, growth retardation, low feed conversion rate. The disease has high morbidity and low mortality, and is widely distributed all over the world. It is one of the most important diseases that cause economic losses in pig farming worldwide. [0003] Mycoplasma hyopneumoniae has all the morphological characteristics of typical mycoplasma, and the cells without cell walls have various shapes. Under the electron microscope, spherical, ring-shaped, filamentous and point-sh...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K39/02A61P31/04
Inventor 孙晔吴金冯忠泽沈青春李秋菊魏晶晶李聪研孙亚波宋潇婷史文艳
Owner 北京中海生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com