Method for integrally driving and metering micro-fluid

Abstract

The invention discloses a method for integrally driving and metering micro-fluid. According to effects on driving the micro-fluid through ICEOF and based on the influence on strain type manganese filaments and polarizable platinum by the micro-fluid, a T-shaped channel is designed, and a driving part and a metering part for the micro-fluid are highly integrated, so that the micro-fluid can be effectively driven and metered, and the flow of the micro-fluid can be automatically adjusted with the combination of a peripheral feedback control circuit. The method is advantageous in that: (1) the micro-fluid can be efficiently driven without valves in a micro-channel by the use of the ICEOF; (2) by the use of an MEMS application concept, the flow can be accurately and integrally metered and driven in the micro-channel through a manner that a polarizable driving element and a strain induction element of the metering part are embedded in the micro-channel; (3) by the design of the peripheral feedback circuit, the micro-pump flow can be output in a controllable manner; and (4) a cylindrical jacket layer is subjected to a semipolar plating treatment for the first time, so that driving effects are obviously enhanced, the input of an external voltage is reduced, energy is saved, and high efficiency is achieved.

Description

technical field [0001] The invention belongs to the field of bioengineering and relates to a method for integrating microfluidic drive and measurement. Background technique [0002] Since the early 1990s, the Swiss Academy of Sciences first proposed the concept of a micro-total analysis system based on micro-electromechanical systems (MEMS). Since then, the analysis technology in micro-channels of microfluidic chips has developed rapidly and has become one of the world's cutting-edge scientific and technological fields. one. A typical microfluidic driving part is only a few square centimeters, using micromachining technology to etch microchannels with a width and depth of only tens to hundreds of microns on the surface of glass, PDMS and other materials, and applying external force to drive the microfluidic flow in the channel, Complete the injection operation. In recent years, with the gradual deepening of microfluidic research, the focus of microfluidic research has shif...

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Problems solved by technology

[0003] In the current microfluidic driving design, the most successful driving method is electroosmotic driving (EOF), but electroosmotic driving still has certain deficiencies. Strong electric field strength leads to the Joule heating effect, which affects the electric field and flow field; while the AC applied electric field that weakens the Joule heating effect will cause the average driving effect of the microfluid to be zero; the electric potential of the wall double layer in electroosmosis driving is generally less than 100mV, The transmission effect is not ideal

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