A double-effect dropping pill for enhancing body immunity and memory and preparation method thereof

A technology of immunity and memory, applied in medical preparations containing active ingredients, pill delivery, pharmaceutical formulations, etc., to achieve the effects of safe condensate material, short process cycle, and simple equipment

Active Publication Date: 2018-02-27
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current research hotspots mainly focus on the functional activity of Korean pine nut oil and the development of Korean pine nut beverage products. In the process of extracting Korean pine nut oil, most of the by-product Korean pine seed meal is treated as waste. There are few reports on the research and development of active peptides from seed meal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] With a molecular weight of 3000-10000Da, a carbon clearance phagocytosis index of 6.5%, and a peritoneal macrophage phagocytosis rate of fluorescent microspheres of 35%, after 40 days of intragastric administration to mice, the incubation period of the channel water maze was 38 seconds, and the number of errors was 8 times. The protein peptide of Korean pine seed meal is used as a raw material, and 10 g is weighed for subsequent use. To prepare a condensing agent, weigh 1L of liquid paraffin and 2L of simethicone oil for later use. Prepare the matrix, weigh 25g of PEG-4000 and 35g of PEG-6000, heat it in a water bath to a molten state, and keep the temperature at 80°C. After 40 minutes, add the protein peptide powder of Korean pine seed meal into the molten mixed matrix, mix well, and keep The temperature was constant at 80°C. Set the parameters of the dropping pill machine, the refrigeration temperature is 1°C, the oil bath temperature is 40°C, the dripping pan temper...

Embodiment 2

[0027] With a molecular weight of 3000-10000Da, a carbon clearance phagocytosis index of 7.5%, and a peritoneal macrophage phagocytosis rate of fluorescent microspheres of 28%, after 40 days of gavage to mice, the incubation period of the channel water maze is 39 seconds, and the number of errors is 5 times. The protein peptide of Korean pine seed meal is used as a raw material, and 10 g is weighed for subsequent use. To prepare a condensing agent, weigh 1L of liquid paraffin and 1L of simethicone, and set aside. To prepare the matrix, weigh 35g of PEG-4000 and 25g of PEG-6000, heat it in a water bath to a molten state, and keep the temperature at 80°C. After 40 minutes, add the protein peptide powder of Korean pine seed meal into the molten mixed matrix, mix well, and keep The temperature was constant at 80°C. Set the parameters of the dropping pill machine, the cooling temperature is 3°C, the oil bath temperature is 45°C, the drip pan temperature is 50°C, the air valve pres...

Embodiment 3

[0029] With a molecular weight of 3000-10000Da, a carbon clearance phagocytosis index of 7.8%, and a peritoneal macrophage phagocytosis rate of fluorescent microspheres of 28%, after 40 days of intragastric administration to mice, the incubation period of the channel water maze was 32 seconds, and the number of errors was 2 times. The protein peptide of Korean pine seed meal is used as a raw material, and 10 g is weighed for subsequent use. To prepare a condensing agent, weigh 2L of liquid paraffin and 1L of simethicone, and set aside. Prepare the matrix, weigh 50g of PEG-4000 and 50g of PEG-6000, heat it in a water bath to a molten state, and keep the temperature at 80°C. After 40 minutes, add the protein peptide powder of Korean pine seed meal into the molten mixed matrix, mix well, and keep The temperature was constant at 80°C. Set the parameters of the dropping pill machine, the cooling temperature is 1°C, the oil bath temperature is 40°C, the drip pan temperature is 45°C...

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PUM

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Abstract

A double-effect drop pill that enhances the body's immunity and memory and its preparation method belongs to the technical field of intensive processing of agricultural and sideline products and the comprehensive utilization of by-products. It is prepared by matrix formulation, condensing agent formulation, peptide powder and matrix formulation, and dripping pills. Treatment, cooling and drying, etc., the molecular weight is 3000-10000Da, the carbon clearance phagocytosis index is 6.5%-8.5%, the phagocytosis rate of peritoneal macrophages is 25%-35%, and the incubation period of the channel water maze is short. The pine nut source with fewer mistakes, high-quality appearance (strong hardness, full roundness, no tailing), dissolution time limit of less than 8 minutes, and pill weight difference of less than 0.2g can help enhance the body's immunity and memory. Dropping pills.

Description

technical field [0001] The invention belongs to the technical field of intensive processing of agricultural products and comprehensive utilization of by-products, and specifically relates to a double-effect dropping pill prepared from a red pine seed protein peptide to enhance body immunity and memory and a preparation method thereof. Background technique [0002] Food-derived active peptides have a wide range of sources, high safety, and a variety of physiological functions. They are currently a hot topic in research. They have high potential for nutrition and health, and their development prospects are very promising. According to different sources, there are mainly the following categories: milk peptides, soybean peptides, corn peptides, nut peptides, pea peptides, livestock peptides, aquatic peptides, silk protein peptides and compound peptides. Its main physiological functions include: promoting amino acid absorption and protein synthesis, promoting mineral element abso...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K38/02A23L33/00A61P37/04A61P25/28
Inventor 林松毅刘轩廷黄延军
Owner JILIN UNIV
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