Traditional Chinese medicine composition for treating prosopalgia generated after acoustic neuroma operation

A technology for trigeminal neuralgia and acoustic neuroma, applied in the field of medicine, can solve problems such as intolerance of drowsiness, dizziness, large toxic and side effects of drugs, liver and kidney damage, etc. Effect

Inactive Publication Date: 2015-11-04
QINGDAO YUNTIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, western medicines for clinical treatment of trigeminal neuralgia are mostly psychotropic drugs. Carbamazepine is effective for pain relief in 70% of patients, but about 1/3 of patients cannot tolerate its side effects such as drowsiness, dizziness, and g

Method used

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  • Traditional Chinese medicine composition for treating prosopalgia generated after acoustic neuroma operation

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Effect test

Embodiment 1

[0013] Embodiment 1 Chinese medicine composition mixture of the present invention

[0014] Prescription: 15 parts of asarum, 15 parts of dodder, 6 parts of mugwort, 10 parts of salvia miltiorrhiza, 10 parts of oyster, 6 parts of woody fragrance, 8 parts of Imperata rhizome, 10 parts of Achyranthes bidentata, 20 parts of Shichangpu, 10 parts of berberine, Cyperus cyperus 9 parts, Acanthopanax 10 parts, Notopterygium 15 parts, Poria cocos 10 parts.

[0015] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 30 minutes, decoct twice for 2 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 Extraction, the relative density is the test result at 60 degrees Celsius, add ethanol to alcohol content of 75% (v / v), let it stand for 24 hours, take the supernatant, reclaim the ethanol concentration, add water to ...

Embodiment 2

[0016] Embodiment 2 Chinese medicine composition mixture of the present invention

[0017] Prescription: 15 parts of asarum, 15 parts of dodder, 6 parts of mugwort, 10 parts of salvia miltiorrhiza, 10 parts of oyster, 6 parts of woody fragrance, 8 parts of Imperata rhizome, 10 parts of Achyranthes bidentata, 20 parts of Shichangpu, 10 parts of berberine, Cyperus cyperus 9 parts, Acanthopanax 10 parts, Notopterygium 15 parts, Poria cocos 10 parts, Caulis Spatholobus 6 parts, Rhizoma Chuanxiong 12 parts and Herb Rue 8 parts.

[0018] Preparation method: Take the medicinal materials of the above weight components, add water 5 times the total weight of the medicinal materials, soak for 30 minutes, decoct twice for 2 hours each time, filter, combine the filtrates, and concentrate the filtrates under reduced pressure to a relative density of 1.1 Extraction, the relative density is the test result at 60 degrees Celsius, add ethanol to alcohol content of 75% (v / v), let it stand for 24...

Embodiment 3

[0019] Embodiment 3 Chinese medicine composition tablet of the present invention

[0020] Prescription: 15 parts of asarum, 15 parts of dodder, 6 parts of mugwort, 10 parts of salvia miltiorrhiza, 10 parts of oyster, 6 parts of woody fragrance, 8 parts of Imperata rhizome, 10 parts of Achyranthes bidentata, 20 parts of Shichangpu, 10 parts of berberine, Cyperus cyperus 9 parts, Acanthopanax 10 parts, Notopterygium 15 parts, Poria cocos 10 parts.

[0021] Preparation method: Take each medicinal material of the above weight components, add water 10 times the total weight of the medicinal materials, soak for 60 minutes, decoct once for 1 hour each time, filter, combine the filtrate, and concentrate the filtrate under reduced pressure to a relative density of 1.25 Extraction extract, the relative density is the test result at 60 degrees Celsius, add ethanol to alcohol content of 80% (v / v), let it stand for 24 hours, take the supernatant, reclaim the ethanol to concentrate, vacuum ...

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Abstract

The invention belongs to the field of traditional Chinese medicine and relates to a traditional Chinese medicine composition for treating prosopalgia generated after an acoustic neuroma operation and a preparation method of the traditional Chinese medicine composition. For the defects that in the prior art, chemotherapeutic drugs for the prosopalgia at present are large in hepatoxicity and poor in curative effect, the traditional Chinese medicine composition for treating or preventing the prosopalgia generated after the acoustic neuroma operation comprises 15 parts of manchurian wildginger, 15 parts of dodder, 6 parts of felon herbs, 10 parts of roots of red-rooted salvia, 10 parts of oysters, 6 parts of costustoot, 8 parts of cogongrass rhizomes, 10 parts of roots of bidentate achyranthes, 20 parts of grassleaf sweelflag rhizomes, 10 parts of coptidis rhizomes, 9 parts of nutgrass galingale rhizomes, 10 parts of acanthopanax roots, 15 parts of notopterygium roots and 10 parts of poria cocos. The traditional Chinese medicine composition has the good treatment effect on treating or preventing the prosopalgia generated after the acoustic neuroma operation, meanwhile, the side effect of the composition is low, and the traditional Chinese medicine composition has remarkable clinic promotional value.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine composition for treating trigeminal neuralgia after acoustic neuroma surgery and a preparation method thereof. Background technique [0002] Acoustic neuroma refers to the tumor originating from the auditory nerve sheath. It is a benign tumor. The exact name should be acoustic nerve sheath tumor. It is one of the common intracranial tumors, accounting for 7% to 12% of intracranial tumors and 80% of cerebellopontine angle tumors. ~95%. It is more common in adults, the peak is between 30 and 50 years old, and it is rare in those under 20 years old. Solitary acoustic neuroma in children is very rare. So far, it has only been case reports. No significant gender difference. Left and right incidences are similar, occasionally bilateral. The main clinical manifestations are cerebellopontine angle syndrome and increased intracranial pressure. Its cli...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P25/02A61K35/618
Inventor 不公告发明人
Owner QINGDAO YUNTIAN BIOTECH
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