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Preparation process of modified chitosan composite gel moisture retention adhesive bandage

A composite gel and preparation technology, which is applied in the field of medical devices, can solve problems such as limited application range, achieve good antibacterial effect, good moisturizing and moisture absorption performance, and relieve physical and mental pain.

Inactive Publication Date: 2015-11-25
青岛高新区尚达医药研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, because it is insoluble in water and most organic solvents, it is only soluble in dilute acids, which limits its application to a large extent.

Method used

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  • Preparation process of modified chitosan composite gel moisture retention adhesive bandage
  • Preparation process of modified chitosan composite gel moisture retention adhesive bandage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] 1. Weigh 50g of carbomer neutralized with NaOH for later use.

[0032] 2. Weigh 4 g of hydroxypropyl chitosan aqueous solution with a concentration of 1.5 mg / ml for subsequent use.

[0033] 3. Weigh 0.3g aluminum glyoxate and 3g NP700, dissolve with 15g glycerol for later use.

[0034] 4. Weigh 0.2g of citric acid and 0.2g of tartaric acid, add 25g of water to dissolve and set aside.

[0035] 5. Add 2 and 3 into 1 and stir evenly;

[0036] 6. Slowly add 4 to 1, stir evenly, and fully react.

Embodiment 2

[0038] 1. Weigh 40g of carbomer neutralized with NaOH for later use.

[0039] 2. Weigh 4 g of hydroxypropyl chitosan aqueous solution with a concentration of 1.5 mg / ml for subsequent use.

[0040] 3. Weigh 0.3g aluminum glyoxate and 4.5g NP700, and dissolve them with 20g glycerol for later use.

[0041] 4. Weigh 0.4g of lactic acid and 0.1g of tartaric acid, add 30g of water to dissolve and set aside.

[0042] 5. Add 2 and 3 into 1 and stir evenly;

[0043] 6. Slowly add 4 to 1, stir evenly, and fully react.

Embodiment 3

[0045] 1. Weigh 60g of carbomer neutralized with NaOH for later use.

[0046] 2. Weigh 2 g of hydroxypropyl chitosan aqueous solution with a concentration of 1.5 mg / ml for subsequent use.

[0047] 3. Weigh 0.3g aluminum glyoxate and 4g NP700, and dissolve them with 12g glycerol for later use.

[0048] 4. Weigh 1.3g lactic acid, 0.2g citric acid, 0.2g tartaric acid, add 20.2g water to dissolve and set aside.

[0049] 5. Add 2 and 3 into 1 and stir evenly;

[0050] 6. Slowly add 4 to 1, stir evenly, and fully react.

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PUM

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Abstract

The present invention relates to a preparation process of a modified chitosan composite gel moisture retention adhesive bandage, which comprises a nonwoven layer, a moisture retention layer and a protective layer from bottom to top, wherein the moisture retention layer consists of a modified chitosan gel. The preparation process designs the preparation method of the adhesive bandage. The adhesive bandage has the characteristics of bacteriostasis, inflammation relief, bleeding and pain stopping, and no wound adhesion, and provides a moist environment to accelerate wound healing, and mitigates the physic and spirit pain of the patients.

Description

technical field [0001] The invention belongs to the field of medical devices, and in particular relates to a preparation process of a modified chitosan composite gel moisturizing band-aid. Background technique [0002] With the improvement of people's living standards, people's requirements for the details of life are getting higher and higher, and they know how to enjoy life more and more. Minor traumas in life are inevitable. While people meet the basic medical security, they also put forward higher requirements for trauma care. Most of the existing band-aids are simple in structure, and only perform simple physical hemostasis and bandaging on the wound, which makes the wound easy to be infected, difficult to heal, and easy to leave scars. In addition, dry band-aids and dressings tend to stick to the wound when the wound is scarred and replaced, causing secondary injury to the patient, slowing down the healing process, and bringing mental pain and financial burden to the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/44A61F13/02A61M35/00
Inventor 李育强刘红梅韩超智倩倩李园园隋洪楠侯风君
Owner 青岛高新区尚达医药研究所
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