Distance-field-fusion-based hippocampus segmentation method of MR image
A technology of distance field and hippocampus, which is applied in the field of medical image analysis and can solve problems such as the limitation of segmentation accuracy
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Embodiment 1
[0059] A method of hippocampus segmentation in MR images based on distance field fusion, which is based on two assumptions:
[0060] Ⅰ. The MR image block and the DF image block are located on two nonlinear manifolds, and any MR image block can be linearly expressed by its neighbor samples in the local space of the manifold;
[0061] Ⅱ. Under local constraints, the mapping from MR manifold to DF manifold is approximately a diffeomorphism mapping.
[0062] The MR image hippocampus segmentation method based on distance field fusion is carried out through the following steps:
[0063] (1) Normalize the initial MR test image to be segmented, remove the skull and offset field, and obtain the normalized MR test image. Specifically, the gray scale normalization method is used to normalize the MR test image, the BET algorithm is used to remove the skull, and the N4 algorithm is used to remove the offset field.
[0064] (2) Register the MR training set image in the pre-prepared train...
Embodiment 2
[0098] In order to verify the validity of the method of the present invention, the verification is carried out on the basis of 35 groups of MR brain data included in the database. The data of each set of MR brain data includes the T1-weighted MR images of the same patient and the corresponding labeled images of the hippocampus, among which 20 sets of data are randomly selected as the training set, and the remaining 15 sets of data are used as the test set. In the experiment, only the MR images of the subjects in the test set are used, and the labeled images of the hippocampus in the corresponding database are not used.
[0099] The present invention is based on the distance field fusion MR image hippocampus segmentation method, the method is based on two assumptions:
[0100] Ⅰ. The MR image block and the DF image block are located on two nonlinear manifolds, and any MR image block can be linearly expressed by its neighbor samples in the local space of the manifold;
[0101] ...
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