Production method of gamma-oryzanol

A production method and technology of oryzanol, which is applied in the field of γ-oryzanol production, can solve the problems of low purity of crude γ-oryzanol, low yield of crude γ-oryzanol, unreasonable and effective procedures, etc., to shorten the time of filtration and improve the purity , good effect

Active Publication Date: 2016-02-24
XIAMEN UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] Existing methods for extracting crude gamma-oryzanol, the procedure is not reasonable and effective, the filtration time is long, the purity of the cr...

Method used

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  • Production method of gamma-oryzanol
  • Production method of gamma-oryzanol

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Embodiment 1: filter residue preparation

[0042] Extract the rice bran oil from the rice bran oil soapstock with n-hexane, the obtained rice bran oil has a solubility of 1.5-2.0% γ-oryzanol, add caustic soda for deacidification, and obtain alkaline oil residue, then add sulfuric acid, add hydrolysis to obtain black oil and refined rice oil; the black oil is esterified with methanol and sulfuric acid, and then distilled under reduced pressure at 180 degrees at 5 mmHg, and the residue obtained is the filter residue, which contains about 30% gamma-oryzanol.

Embodiment 2

[0043] Embodiment 2: production of gamma-oryzanol crude product

[0044] 1. the filter residue 190Kg gained in embodiment 1 is poured into 2000L dissolving tank; The filter residue is alkaline, and solubility is 30% gamma-oryzanol;

[0045] ② Add 270Kg of methanol and mix, then add 300Kg of hexane and stir for about an hour; the stirring speed is 60 rpm;

[0046] ③Put in 16Kg acetic acid for neutralization, stir and reflux in the dissolving tank for 30 minutes to obtain the mixture;

[0047] ④Heat the mixture in a water bath to 50°C, heat, stir and reflux for about 30 minutes;

[0048] ⑤Continue to pour 36L of water for stirring; the stirring rate is 60 rpm, and stand for one hour after the stirring is stopped; the crude product γ-oryzanol is precipitated;

[0049] ⑥ The solution is automatically stratified, the upper layer is a hexane solution containing pigments, impure oils, and viscous substances; the lower layer is a crude product γ-oryzanol precipitate and methanol dis...

Embodiment 3

[0054] Embodiment 3: comparative test

[0055] This comparative test is actually the method used in the prior art.

[0056] 1. pour 190Kg of embodiment 1 gained filter residue into 2000L dissolving tank; Described filter residue is alkaline, contains 20-30% gamma-oryzanol;

[0057] ②Add 470Kg of methanol to mix, and circulate in a water bath at 60°C for 2 hours; cool to 40°C to separate layers, and take the upper filtrate;

[0058] ③ Add 16Kg acetic acid to the upper layer filtrate to neutralize and separate out the γ-oryzanol precipitated particles, then stir and reflux for 30 minutes;

[0059] ④Heat in a water bath to 50°C for about 30 minutes; then add 160Kg of methanol;

[0060] ⑤ Pour 36L of water into it for stirring, and let it stand for one hour after the stirring stops;

[0061] ⑥Filter for 5 hours;

[0062] ⑦ Collect the precipitated particles of γ-oryzanol and dry them at low temperature at 40°C to obtain crude γ-oryzanol; the methanol waste liquid is recovered ...

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Abstract

The invention discloses a production method of gamma-oryzanol. The production method comprises the steps: pouring filter residues in a dissolving tank; adding methanol, mixing, then adding hexane, and stirring; adding acetic acid, neutralizing, and carrying out stirring reflux; heating to 50 DEG C in a water bath, heating up, and carrying out stirring reflux; adding water, continuing to stir, and then allowing to stand for an hour; precipitating to obtain a crude product gamma-oryzanol; allowing the solution to be automatically layered, wherein an upper layer is a hexane solution and a lower layer is a crude product gamma-oryzanol precipitate and a methanol dissolving layer; shunting the upper layer and the lower-layer methanol dissolving layer; carrying out water-bath heating of the lower layer; carrying out reduced pressure filtration on the crude product gamma-oryzanol precipitate and the methanol dissolving layer after water-bath heating, wherein a filter paper upper layer is crude gamma-oryzanol; adding hexane to crude gamma-oryzanol precipitated particles, and washing out impurities which can be dissolved in hexane; and collecting gamma-oryzanol precipitated particles, and drying at low temperature. The method reduces the methanol use amount, the added hexane solvent can be recycled, the purity of the crude product gamma-oryzanol is improved, and the filtration time is shortened.

Description

technical field [0001] The invention relates to the field of preparation of oryzanol, in particular to a production method of gamma-oryzanol. Background technique [0002] γ-Oryzanol is isolated and extracted from rice bran oil and rice germ oil, and is used as a raw material for food and medicine. As a medicinal agent, we know that it stimulates autonomic nerves and gonads, and activates menopausal disorders and human aging. [0003] Existing methods for extracting crude gamma-oryzanol, the procedure is not reasonable and effective, the filtration time is long, the purity of the crude gamma-oryzanol extracted is low, and the yield of crude gamma-oryzanol is low. Therefore, an improved crude gamma-oryzanol is urgently needed production method. Contents of the invention [0004] The purpose of the present invention is to provide a short filtration time, the extracted crude product of gamma-oryzanol has a high purity and a high yield of crude gamma-oryzanol. [0005] To a...

Claims

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Application Information

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IPC IPC(8): C07J53/00
CPCC07J53/001
Inventor 姚晓斌姚惠琳李怡李一多
Owner XIAMEN UNIV OF TECH
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