Pharmaceutical composition for treating chicken coccidiosis and preparation method thereof
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- 河北美荷药业有限公司
- Publication Date
- 2016-03-09
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The invention relates to the technical field of pharmaceutical compositions, in particular to a pharmaceutical composition for treating chicken coccidiosis and a preparation method thereof. Background technique
[0002] Ivermectin is a broad-spectrum antiparasitic drug, which has a good killing effect on internal and external parasites, especially nematodes and arthropods. The insecticidal mechanism is that the drug binds to the specific high-affinity site on the target insect cells, which affects the permeability of the cell membrane to Cl-, and then causes the nerve cells of nematodes and muscle cells of arthropods to inhibit the neurotransmitter γ -The release of aminobutyric acid (GABA) is increased, and the Clˉ channel controlled by glutamic acid is opened to enhance the permeability of the neural membrane to Clˉ. The excitatory post-synaptic potential generated by the postsynaptic membrane weakens, and the post-synaptic neuron cannot enter the e...