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Method for producing neomycin by replacing fermentation raw materials with amino acid fermentation mushroom dregs

A technology for fermenting raw materials and amino acids, applied in the field of neomycin production, which can solve the problems of high cost of fermented raw materials, environmental pollution, and high cost of bacterial residue treatment, and achieve the effect of reducing the cost of neomycin fermentation formula

Active Publication Date: 2016-03-16
YICHANG SANXIA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is to provide a method for producing neomycin by using amino acid fermentation slag instead of fermentation raw material, which can solve the problem of high processing cost of slag produced after amino acid fermentation production, environmental pollution, and neomycin fermentation to produce fermentation raw material The problem of high cost enables the utilization of amino acid fermentation residue waste and reduces the production cost of neomycin fermentation, greatly improving the company's benefits

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  • Method for producing neomycin by replacing fermentation raw materials with amino acid fermentation mushroom dregs
  • Method for producing neomycin by replacing fermentation raw materials with amino acid fermentation mushroom dregs
  • Method for producing neomycin by replacing fermentation raw materials with amino acid fermentation mushroom dregs

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Embodiment 1

[0020] A method for producing neomycin by using amino acid fermentation slag to replace fermentation raw materials, the method comprising the following steps:

[0021] 1) Preparation of amino acid fermentation scum: the waste water after amino acid production is preliminarily filtered to obtain amino acid fermentation slag;

[0022] 2) The amino acid fermentation slag obtained in step 1) is used as a component of a fermentation medium in the fermentative production of neomycin, and partly or completely replaces soybean flour as a fermentation raw material to produce neomycin.

[0023] In step 1), ceramic membranes are used to preliminarily filter the waste water after amino acid production.

[0024] The amino acid fermentation residue obtained in step 1) is detected, and the amino acid residue with a dry matter mass ratio of not less than 10% is used, and the analysis result of total nitrogen in the amino acid residue is ≧45%.

[0025] In step 2), the mass ratio of amino acid...

Embodiment 2

[0029] A method for producing neomycin by using amino acid fermentation slag to replace fermentation raw materials, the method comprising the following steps:

[0030] 1) Preparation of amino acid fermentation scum: the waste water after amino acid production is preliminarily filtered to obtain amino acid fermentation slag;

[0031] 2) The amino acid fermentation slag obtained in step 1) is used as a component of a fermentation medium in the fermentative production of neomycin, and partly or completely replaces soybean flour as a fermentation raw material to produce neomycin.

[0032] In step 1), ceramic membranes are used to preliminarily filter the waste water after amino acid production.

[0033] The amino acid fermentation residue obtained in step 1) is detected, and the amino acid residue with a dry matter mass ratio of not less than 10% is used, and the analysis result of total nitrogen in the amino acid residue is ≧45%.

[0034] In step 2), the mass ratio of soybean po...

Embodiment 3

[0038] Embodiment one

[0039] A method for producing neomycin by using amino acid fermentation slag to replace fermentation raw materials, the method comprising the following steps:

[0040] 1) Preparation of amino acid fermentation scum: the waste water after amino acid production is preliminarily filtered to obtain amino acid fermentation slag;

[0041] 2) The amino acid fermentation slag obtained in step 1) is used as a component of a fermentation medium in the fermentative production of neomycin, and partly or completely replaces soybean flour as a fermentation raw material to produce neomycin.

[0042] In step 1), ceramic membranes are used to preliminarily filter the waste water after amino acid production.

[0043] The amino acid fermentation residue obtained in step 1) is detected, and the amino acid residue with a dry matter mass ratio of not less than 10% is used, and the analysis result of total nitrogen in the amino acid residue is ≧45%.

[0044] In step 2), the...

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Abstract

The invention provides a method for producing neomycin by replacing fermentation raw materials with amino acid fermentation mushroom dregs. The method includes the following steps that 1, the amino acid fermentation mushroom dregs are prepared, wherein wastewater obtained after amino acid production is preliminarily filtered, and then the amino acid fermentation mushroom dregs are obtained; 2, the amino acid fermentation mushroom dregs obtained in the step 1 serve as components of a fermentation medium in neomycin fermentation production, and partially or fully replace soybean meal to serve as fermentation raw materials to produce neomycin. According to the method for producing neomycin by replacing the fermentation raw materials with the amino acid fermentation mushroom dregs, the problems that the treatment cost of mushroom dregs generated after amino acid fermentation production is high, the environment is polluted, and the cost of the fermentation raw materials for neomycin fermentation production is high can be solved, the waste amino acid fermentation mushroom dregs are utilized, the production cost of neomycin fermentation is reduced, and enterprise benefits are greatly increased.

Description

technical field [0001] The invention relates to the field of neomycin production, in particular to a method for producing neomycin by using amino acid fermentation scum to replace fermentation raw materials. Background technique [0002] The fermentation industry mostly uses agricultural and sideline product resources as raw materials. The production strains are inoculated on the culture medium and undergo multi-stage purebred cultivation, and finally produce target products such as amino acids and antibiotics. Therefore, when the target products are extracted, the amount of wastewater produced is large. In addition, a large amount of solid substrates will be discharged into the wastewater during the production process, which will bring pressure to the environmental protection of enterprises. At present, relevant scientific research institutions and amino acid production enterprises in my country have done a lot of work on the treatment process and comprehensive utilization ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12P19/52
CPCC12P19/52
Inventor 沈联兵周宜平史新华江兵张国宪何连明
Owner YICHANG SANXIA PHARMA