Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Autism detection marker and detection method thereof

A detection method and technology for autism, applied in the field of disease detection, can solve problems such as detection delay or misdiagnosis, and achieve the effect of improving specificity and accuracy

Active Publication Date: 2016-06-22
SHENZHEN UNIV
View PDF2 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In view of the above-mentioned deficiencies in the prior art, the purpose of the present invention is to provide a detection marker for autism and its detection method, which aims to solve the problem that the existing detection method has certain subjectivity and easily causes detection delay or misdiagnosis

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Autism detection marker and detection method thereof
  • Autism detection marker and detection method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Sera from children with autism and healthy children were collected separately, and high-throughput proteomics methods were used to compare and analyze the serum of children with autism and healthy children. The results were obtained: Compared with the serum of healthy children, 29 serum differential proteins were obtained in the serum of children with autism, of which 11 expressed proteins were up-regulated and 18 expressed proteins were down-regulated, see Table 1 below for details. Then, the enzyme-linked immunosorbent technology was used to detect the 29 differential proteins one by one, or the protein chip technology was used to detect the 29 differential proteins one by one, and the concentration changes of the detected serum differential proteins were determined. Through the method of high-throughput proteomics, the present invention compares and analyzes the serum of children with autism and the serum of healthy children. Compared with the control, 29 serum differ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an autism detection marker and a detection method thereof. A set of serum differential proteins provided by the invention can be utilized to detect autism. When the serum differential proteins are used for detecting autism, the detection specificity and accuracy can be promoted, and meanwhile, the result is objective, and the autism detection marker is better than a single disease marker. A high-flux proteomics method is adopted for confirming if the serum differential proteins exist in serum; ELISA technique is adopted for detecting these proteins one by one or a protein chip technique is adopted for detecting these proteins at the same time; the concentration change of the detected serum differential proteins can be confirmed. Compared with the present detection method (autism detection table), the detection method provided by the invention has the advantages of high specificity, sensitivity and accuracy.

Description

technical field [0001] The invention relates to the technical field of disease detection, in particular to an autism detection marker and a detection method thereof. Background technique [0002] Autism, also known as autism, is a neurodevelopmental disorder, and its incidence is increasing year by year. Since the etiology and pathogenesis have not yet been elucidated, there are currently no specific therapeutic drugs and specific detection markers, but early detection and early intervention can significantly improve detection and treatment. The current detection of autism is mainly based on scales, clinical symptoms, descriptions of patients or family members, clinical experience of clinicians, etc., which has a certain degree of subjectivity, which may easily cause detection delays or misdiagnosis. [0003] Therefore, the prior art still needs to be improved and developed. Contents of the invention [0004] In view of the above deficiencies in the prior art, the purpos...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/68G01N21/76
CPCG01N21/76G01N33/6803G01N2800/28
Inventor 沈立明陈友姣冯承芸
Owner SHENZHEN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com