Optoacoustic microscopic imaging method and device based on low-rank matrix approximation

Abstract

The invention relates to an optoacoustic microscopic imaging method and a device based on low-rank matrix approximation, and relates to the field of optoacoustic microscopic imaging. The method comprises steps of according to a preset sampling ratio, determining a sampling matrix including 0 elements and 1 elements, wherein the occupied ratio of the 1 elements in the sampling matrix is the preset sampling ratio; according to the sampling matrix, carrying out optoacoustic microscopic data acquisition on a to-be-imaged region so as to obtain an optoacoustic microscopic data matrix; according to the optoacoustic microscopic data matrix, establishing an image restoration model; and according to a low-rank matrix approximation algorithm, solving the image restoration model so as to obtain a restored optoacoustic microscopic image, thereby achieving optoacoustic microscopic imaging on the to-be-imaged region. According to the invention, while optoacoustic data acquisition time is saved, it is ensured that the resolution ratio of the restored optoacoustic microscopic image will not be severely damaged; restoration speed of the optoacoustic microscopic image is increased; and noise is reduced.

Description

technical field [0001] The invention relates to the field of photoacoustic microscopic imaging, in particular to a photoacoustic microscopic imaging method and device based on low-rank matrix approximation. Background technique [0002] Photoacoustic imaging technology is a new non-invasive non-destructive medical imaging technology developed in recent years, which effectively combines the advantages of high penetration of pure ultrasound imaging and high contrast of pure optical imaging. It includes three main imaging methods: Photoacoustic Microscopy (PAM), Photoacoustic Computed Tomography (PACT) and Photoacoustic Endoscopy (PAE). Among them, the optical microscope imaging technology PAM adopts point-by-point scanning to obtain images, so it does not require specific image reconstruction algorithms. PAM can be further divided into: Optical-Resolution Photoacousic Microscopy (OR-PAM) and Acoustical-Resolution Photoacousic Microscopy (AR-PAM). [0003] However, the proble...

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Problems solved by technology

[0003] However, the problem with the existing technology is that, for OR-PAM, increasing the optical numerical aperture can improve the lateral resolution, but the imaging depth will decrease; for AR-PAM, the resolution is determined by the bandwidth of the ultrasonic transducer As well as the center frequency, the higher the performance of the ultrasonic transducer, the higher the resolution, so the resolution is often improved by improving the imaging system or method, but the cost will increase

Therefore, the way of point-by-point scanning of the imaging area in the prior art requires a long time and high cost

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