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Angle composite speckle denoising method and system for full-channel modulation encoding

A modulation and coding, all-channel technology, applied in the field of angular composite speckle noise reduction method and system, can solve the problems of limiting imaging speed, etc., achieve the effects of speckle noise reduction, image signal-to-noise ratio improvement, and clear detail information

Inactive Publication Date: 2016-08-17
ZHEJIANG UNIV
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Problems solved by technology

However, due to the special beam setting of the sample arm in this method, only a narrow modulation spectrum of half-channel (only positive or negative frequency components) is used to realize angle encoding in the spatial frequency domain, which limits the range of modulation spectrum segmentation. number to satisfy the appropriate degraded lateral resolution due to segmentation
In addition, in order to obtain the Doppler frequency shift so that the conjugate overlapping transverse modulation spectrum can be completely distinguished, it is necessary to ensure a sufficiently high transverse sampling rate in one B-scan, which limits the imaging speed of the system

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[0031] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0032] figure 1 Schematic diagram of the probe beam scanning of the sample arm in the OCT system. the following pair figure 1 Schematic diagram for detailed description.

[0033] In the sample arm of the OCT system, the effective diameter size of the probe beam (ie, the mark ①) irradiated on the collimating objective lens (ie, the mark ④) should be as large as possible to obtain a higher lateral resolution of the system imaging. When a collimated beam with a certain width is irradiated to the center of the rotating shaft of the scanning mirror of the sample arm (ie, mark ②), the positions of different widths of the beam are offset from the center of the rotating shaft (ie, mark ③) by ±δ. This offset introduces the modulation frequency f m , so that the lateral scan spectrum in the spatial frequency domain is modulated. Modulation frequency f m Linea...

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Abstract

The invention discloses an angle composite speckle denoising method and system for full-channel modulation encoding. Generally, low-coherence detection is adopted during optical coherence tomography (OCT) imaging, and images obtained through the technology are likely to be influenced by speckle noise. A conjugated structural mirror image is deleted in a depth domain, a complex-value OCT interference spectrum is reconstructed, and a wide transverse scanning modulation spectrum without the conjugated structural mirror image is obtained in a full-channel space frequency domain; by means of the modulation spectrum, modulation encoding of detection light in different incident angles is achieved, and mutually independent incident angle resolution structural subgraphs are obtained by segmenting the modulation spectrum; the obtained structural subgraphs are subjected to composite average to obtain a final OCT structural image. The OCT structural image is obtained through the angle composite technology, speckle noise is reduced, the signal-to-noise ratio is increased, and structure details are clearer. Besides, the full-channel transverse scanning modulation spectrum is used for angle encoding and compositing so that speckle noise can be reduced and image quality can be improved to the maximum extent.

Description

technical field [0001] The present invention relates to optical coherence tomography (Optical Coherence Tomography, OCT), in particular to a method and system for denoising angular composite speckle with full-channel modulation and coding. technical background [0002] OCT technology is an imaging technology that is widely used in the biomedical field to detect the microstructure of biological tissues. It has the advantages of non-invasiveness, high speed and high resolution. The OCT technology uses the detected light intensity changes of the backscattered light from the biological sample to reflect the reflection information inside the sample and reconstruct the tomographic image of the sample. OCT imaging is susceptible to the interference of speckle noise due to the low-coherence interferometric detection. Speckle noise arises from the effect of coherent superposition of trains of light waves with random phase distributions. The existence of speckle noise will cause the...

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Application Information

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IPC IPC(8): A61B5/00
CPCA61B5/7203A61B5/0066A61B5/7228
Inventor 李鹏李培周丽萍丁志华
Owner ZHEJIANG UNIV
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