Method for performing whole genome selective breeding by selecting extreme character individual

Abstract

The invention discloses a method for performing whole genome selective breeding by selecting extreme character individuals. The method comprises the following steps: as for a certain amount of characters, selecting part of individuals of which the character expression is extreme, wherein the individuals of highest character expression and the individuals of lowest character expression respectively account for one half; constructing an estimation group, and performing character measurement on the estimation group; performing genome sequencing and whole genome SNP label excavation on an extreme character reference group and the estimation group; calculating the breeding effect value of each SNP label according to phenotypic values and gene type information of the extreme individuals, performing whole-genome typing on the estimation group so as to obtain the breeding values of the individuals in the estimation group, and performing final seed selection on the estimation group. According to the method, the influence on genomic estimated breeding value estimation accuracy is as less as possible, and the genome sequencing expense is greatly saved; the influence of size of a reference group on the genome selection accuracy is reduced by virtue of the extreme individuals, thereby being beneficial to relevant research on rare sample species and providing a new thought on performing genome group selection on various species.

Description

technical field [0001] The invention relates to the fields of bioinformatics and genome selective breeding, in particular to a method for selecting individuals with extreme traits to carry out whole genome selective breeding. Background technique [0002] Breeding is an important part of animal and plant breeding in agricultural breeding, and an important method for cultivating and maintaining fine varieties. Traditional artificial breeding is to select directly through the economic traits of animals and plants. Since most species in agriculture have undergone artificial breeding for a long time, the application effect of traditional artificial selection methods in many species in modern agriculture is becoming more and more limited. [0003] With the in-depth research on gene location and function related to animal and plant genomes and important traits, Meuwissen et al. proposed in 2001 a method for molecular breeding using full gene marker typing, namely genome selective...

AI Technical Summary

Problems solved by technology

Although there are gene chips and whole-genome sequencing biological genes that can be used for large-scale genotyping, the above-mentioned chips and sequencing are expensive, and the cost is considerable if all reference populations are sequenced

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