Method for performing whole genome selective breeding by selecting extreme character individual

A whole-genome, selective breeding technology, applied in special data processing applications, instruments, electrical digital data processing, etc., can solve problems such as high cost and high cost, and achieve the effect of reducing scale and saving sequencing costs.

Active Publication Date: 2016-08-17
XIAMEN SHENGJI TECH CO LTD
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Problems solved by technology

Although there are gene chips and whole-genome sequencing biological genes that can be used for large-scale genotyping, the

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  • Method for performing whole genome selective breeding by selecting extreme character individual
  • Method for performing whole genome selective breeding by selecting extreme character individual

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Embodiment Construction

[0034] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0035] see Figure 1~2 , in an embodiment of the present invention, a method for selecting individuals with extreme traits to carry out genome-wide selection breeding, the genome selection data provided by the XII QTL-MAS meeting includes the following steps:

[0036] (1) Test population and labeling information

[0037] The test population is the simulated population used in the XII QTL-MAS (http: / / www.ncbi.nlm.nih.gov / pubmed / 19278535?dopt=Abstract) workshop...

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Abstract

The invention discloses a method for performing whole genome selective breeding by selecting extreme character individuals. The method comprises the following steps: as for a certain amount of characters, selecting part of individuals of which the character expression is extreme, wherein the individuals of highest character expression and the individuals of lowest character expression respectively account for one half; constructing an estimation group, and performing character measurement on the estimation group; performing genome sequencing and whole genome SNP label excavation on an extreme character reference group and the estimation group; calculating the breeding effect value of each SNP label according to phenotypic values and gene type information of the extreme individuals, performing whole-genome typing on the estimation group so as to obtain the breeding values of the individuals in the estimation group, and performing final seed selection on the estimation group. According to the method, the influence on genomic estimated breeding value estimation accuracy is as less as possible, and the genome sequencing expense is greatly saved; the influence of size of a reference group on the genome selection accuracy is reduced by virtue of the extreme individuals, thereby being beneficial to relevant research on rare sample species and providing a new thought on performing genome group selection on various species.

Description

technical field [0001] The invention relates to the fields of bioinformatics and genome selective breeding, in particular to a method for selecting individuals with extreme traits to carry out whole genome selective breeding. Background technique [0002] Breeding is an important part of animal and plant breeding in agricultural breeding, and an important method for cultivating and maintaining fine varieties. Traditional artificial breeding is to select directly through the economic traits of animals and plants. Since most species in agriculture have undergone artificial breeding for a long time, the application effect of traditional artificial selection methods in many species in modern agriculture is becoming more and more limited. [0003] With the in-depth research on gene location and function related to animal and plant genomes and important traits, Meuwissen et al. proposed in 2001 a method for molecular breeding using full gene marker typing, namely genome selective...

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Application Information

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IPC IPC(8): G06F19/24
CPCG16B40/00
Inventor 邱和松
Owner XIAMEN SHENGJI TECH CO LTD
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