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Antibiotic substitute feed additive, its formula, feed with antibiotic substitute feed additive and production method of feed with antibiotic substitute feed additive

A feed additive and a technology to replace antibiotics, applied in animal feed, animal feed, pharmaceutical formula, etc., can solve problems such as unsatisfactory application effects, and achieve the effects of improving the living environment and reducing air pollution

Inactive Publication Date: 2016-08-31
张兴龙 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] Although with the efforts of livestock, poultry and pharmaceutical scientists from all over the world, a variety of biological products that partially replace antibiotics have been developed, but the actual application effect is not ideal. So far, there is no product that can completely replace antibiotics.

Method used

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  • Antibiotic substitute feed additive, its formula, feed with antibiotic substitute feed additive and production method of feed with antibiotic substitute feed additive
  • Antibiotic substitute feed additive, its formula, feed with antibiotic substitute feed additive and production method of feed with antibiotic substitute feed additive
  • Antibiotic substitute feed additive, its formula, feed with antibiotic substitute feed additive and production method of feed with antibiotic substitute feed additive

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0085] The preparation method of the present invention replaces antibiotic feed additive formula

[0086] The preparation method of the present invention replaces antibiotic feed additive prescription and comprises the following steps:

[0087] Step 1: Select one (A) or two (A, B) antibacterial ingredients with synergistic effect from the natural antibacterial ingredients;

[0088] Step 2: In vitro tests to screen the factors (a, b, c, d, e, ...) that have positive or no adverse effects on the normal intestinal flora, and find out the appropriate concentration;

[0089] Step 3: Add the result A selected in step 1, or the concentration of A+B lower than the MIC, to the immune enhancement factors selected in step 2, a, b, c, d, e, ...

[0090]A 96-well microplate was used, Staphylococcus aureus and Lactobacillus acidophilus were used as test strains, and 4 wells of each combination were repeated.

[0091]

[0092] The formula combination was selected on the basis of enhance...

Embodiment 2

[0101] Example 2 Antibiotic Substitute Feed Additive Formula

[0102] The formula of antibiotic substitute feed additive obtained by screening in vitro by the above method.

[0103] Non-polluting antibiotic substitute feed additive formula example 1: propolis and germanium replace antibiotic formula (Propolis&Germanium replace Antibiotic formula)

[0104]

[0105]

[0106] Preparation method:

[0107]

[0108] ② Weigh 20 grams

[0109]

[0110] A preparation and packaging operation process (without zeolite powder)

[0111] B Preparation and packaging operation process (including zeolite powder)

[0112]

[0113] ② Weigh 20 grams

[0114]

[0115] Non-Contaminating Antibiotic Alternative Feed Additive Example #2

[0116]

[0117]

[0118] 1. Container:

[0119] Stainless steel pot with lid, (capacity about 2 liters)

[0120] 2. Stirrer: stainless steel spoon

[0121] 3. Stirring method:

[0122] 1) Take the weighed ingredients ①-④, ③ first take ...

Embodiment 3

[0146] Experimental effect of the present invention replacing antibiotic feed additive formula

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PUM

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Abstract

The invention relates to an antibiotic substitute feed additive, a formula of the antibiotic substitute feed additive, feed with the antibiotic substitute feed additive and a production method of the feed with the antibiotic substitute feed additive. The antibiotic substitute feed additive is a natural antibiotic component. The formula of the antibiotic substitute feed additive comprises a natural antibiotic component, trace elements, a compound enzyme, probiotics, prebiotics and an acid preparation. The invention also relates to the production method of the feed with the antibiotic substitute feed additive.

Description

field of invention [0001] The present invention relates to a substitute antibiotic feed additive, a formulation of a substitute antibiotic feed additive, a feed containing the same and a production method thereof. Specifically, the present invention relates to a natural antibacterial ingredient to replace the antibiotic feed additive; the formulation of the alternative antibiotic feed additive of the present invention includes natural antibacterial ingredients, trace elements, compound enzymes, prebiotics, prebiotics and acid preparations, etc.; the present invention The invention also relates to a method of producing a feed comprising it. Background of the invention [0002] my country is the country with the largest output of livestock and poultry products in the world, and it is also one of the countries with the most serious use or abuse of antibiotics. Due to the problem of drug residues, the export volume of most animal products in my country is not high, which seriou...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K10/30A23K10/20A23K10/18A23K20/163A23K20/189A23K20/20A23K20/28A61K36/8962A61K35/644A61K36/19A61P31/04A61K31/702A61K35/747A61K35/742
Inventor 张新凤
Owner 张兴龙
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