Electron irradiation sterilization device and sterilization method for medical hirudo

A technology of electron irradiation and medicinal leech, applied in packaging sterilization and other directions, can solve the problems of reduced curative effect, inactivation of active ingredients, physical or chemical changes, etc., to avoid radiation and ensure completeness.

Active Publication Date: 2016-09-07
CHONGQING DUOPUTAI PHARMA
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Leech is an important traditional Chinese medicinal material. Its active ingredients have high biological activity. For example, if heat sterilization technology is used, the active ingredients in the medicine will be inactivated, resulting in a decrease in the curative effect. Vacuum packaging will also affect the microbial limit of the product. For example, the sterilization step of the unsealed product is likely to cause physical or chemical changes in the drug; when the sealed product is sterilized, conventional sterilization will cause some Incomplete sterilization of medicines because the sterilization source cannot penetrate the packaging
[0004] With the advancement of science and technology, researchers have developed electron beam sterilization methods with limited penetration of the surface. This process can only sterilize the irradiated surface and cannot control the sterilization of the backside, and the control of its dose has not been further improved. , with the maturity of high-energy electron beam irradiation sterilization technology for substances, it is an urgent problem to be solved by using electron beam sterilization to minimize the energy, avoid the generation of radiation, and reduce the harmful effects of radiation on products.

Method used

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  • Electron irradiation sterilization device and sterilization method for medical hirudo
  • Electron irradiation sterilization device and sterilization method for medical hirudo

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Embodiment 1

[0021] A kind of electronic irradiation sterilization device of medicinal leeches according to the present invention comprises a shielding room 4, a high-energy electron beam generator 5, a stacked grid structure 2, and a stacked grid structure transmission device 6, and the shielding room is within 4 minutes. , the outer two floors, the upper layer of the shielding room 4 is fixed with a high-energy electron beam generator 5, and the high-energy electron beams generated by the high-energy electron beam generator 5 are annularly surrounded by a stacked grid structure transmission device 6 on the inner layer of the shielding room 4, and the stacked grid structure The transmission device 6 is provided with a stacked grid structure 2; the stacked grid structure 2 is composed of four partitions 1 in parallel and perpendicular to each other; the high-energy electron beam generator 5 has a working voltage of 60KV and works in a space charge limited state , The peak pulse current inte...

Embodiment 2

[0023] A kind of electronic irradiation sterilization device of medicinal leeches according to the present invention comprises a shielding room 4, a high-energy electron beam generator 5, a stacked grid structure 2, and a stacked grid structure transmission device 6, and the shielding room is within 4 minutes. , the outer two floors, the upper layer of the shielding room 4 is fixed with a high-energy electron beam generator 5, and the high-energy electron beams generated by the high-energy electron beam generator 5 are annularly surrounded by a stacked grid structure transmission device 6 on the inner layer of the shielding room 4, and the stacked grid structure The transmission device 6 is provided with a stacked grid structure 2; the stacked grid structure 2 is composed of four partitions 1 in parallel and perpendicular to each other; the high-energy electron beam generator 5 has a working voltage of 60KV and works in a space charge limited state , The peak pulse current inte...

Embodiment 3

[0025] A kind of electronic irradiation sterilization device of medicinal leeches according to the present invention comprises a shielding room 4, a high-energy electron beam generator 5, a stacked grid structure 2, and a stacked grid structure transmission device 6, and the shielding room is within 4 minutes. , the outer two floors, the upper layer of the shielding room 4 is fixed with a high-energy electron beam generator 5, and the high-energy electron beams generated by the high-energy electron beam generator 5 are annularly surrounded by a stacked grid structure transmission device 6 on the inner layer of the shielding room 4, and the stacked grid structure The transmission device 6 is provided with a stacked grid structure 2; the stacked grid structure 2 is composed of four partitions 1 in parallel and perpendicular to each other; the high-energy electron beam generator 5 has a working voltage of 60KV and works in a space charge limited state , The peak pulse current inte...

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Abstract

The invention discloses an electron irradiation sterilization device and sterilization method for medical hirudo, relates to electron irradiation sterilization, and belongs to the field of processing of Chinese patent medicine. The sterilization method performs electron beam sterilization on packaged hirudo products, and is characterized in that firstly, the packaged hirudo products are divided through utilizing partition plates of which the average density is 0.2 to 0.5 g / cm<3>, wherein the partition plates form stacked block structures; and the packaged hirudo products are placed in the stacked block structures at intervals. According to the method, annular irradiation electron beams are adopted, the packaged hirudo products are arranged in a staggered manner, the method is a sterilization technology in which the plurality of stacked block structures form irradiation carriers, the electron beam sterilization is carried out and the electron beams can be controlled to penetrate through product packages, and the hirudo products do not directly fall off a conveying belt or are not in dynamic contact with a belt part, so that the completeness of sterilization can be further guaranteed, and the inside products and media are protected from being damaged by electron beam penetration and irradiation.

Description

technical field [0001] The invention relates to an electronic radiation sterilization device and a sterilization method, belonging to the field of Chinese patent medicine processing, in particular to an electronic radiation sterilization device and a sterilization method for medicinal leeches. Background technique [0002] In the pharmaceutical industry, the microbial limit is an important control index in the quality standards of pharmaceuticals, especially for injections, oral preparations and other pharmaceuticals that need to enter the metabolism of the human body. However, the pollution of raw materials of medicines and the pollution caused in the production process have prompted the development of sterilization technology. Nowadays, there are many kinds of sterilization techniques for medicines, such as: dry heat sterilization, moist heat sterilization, radiation sterilization, etc. High temperature sterilization is mainly used for heat-stable medicines, while radiatio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B65B55/02
CPCB65B55/02
Inventor 郭平牯杨秀林甘奇超
Owner CHONGQING DUOPUTAI PHARMA
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