Preparation method of radix codonopsis, ramulus cinnamomi and poria cocos preparation

Abstract

The invention discloses a preparation method of a radix codonopsis, ramulus cinnamomi and poria cocos preparation. The preparation method comprises the following steps: (1) taking ramulus cinnamomi and rhizoma zingiberis, adding water, heating, carrying out reflux distillation, and extracting volatile oil; (2) taking and smashing radix codonopsis, radix paeoniae alba, liquorice root, poria cocos, radix polygalae and rhizoma acori tatarinowii, merging the mixture with medicine residue obtained in step (1), adding water of which the pH (Potential of Hydrogen) value is 1.5 to 2.5, heating and extracting; (3) taking and merging fossilizid and concha ostreae with medicine residue obtained in step (2), adding water of which the pH value is 6.5 to 7.0, heating and extracting; (4) adding water of which the pH value is 7.8 to 8.5 in medicine residue obtained in step (3), heating and extracting; (5) merging filter liquor obtained in step (2), step (3) and step (4), concentrating the merged filter liquor into clear cream, adding the volatile oil, uniformly mixing, and adding a carrier or an auxiliary material which is acceptable in pharmacy, thus preparing a medicine preparation. The radix codonopsis, ramulus cinnamomi and poria cocos preparation prepared by utilizing the preparation method disclosed by the invention has the advantages that the content of effective components is high, the bioavailability is high, the radix codonopsis, ramulus cinnamomi and poria cocos preparation is more suitable for a human body to absorb, and the like.

Description

technical field [0001] The invention relates to a preparation method of a Shenzhiling preparation, which belongs to the technical field of traditional Chinese medicine preparations. Background technique [0002] Alzheimer's disease (Alzheimer's disease) is an acquired intellectual impairment syndrome with cognitive impairment as the core symptom. The degree of intellectual impairment is enough to interfere with social or occupational functions. It is a chronic progressive disease. The scope involves various advanced neural functions such as memory, behavior, personality, judgment, attention, visuospatial skills, language, and logical reasoning. According to statistics, dementia has become the fourth largest killer after cardiovascular disease, cancer and stroke, seriously threatening the health and quality of life of the elderly. It is predicted that by 2030, the number of people suffering from Alzheimer's disease in the world will reach 60 million, and there will be 12 mil...

AI Technical Summary

Problems solved by technology

However, the preparation method of Shenzhiling preparations in the prior art, the preparation process is to extract volatile oil from part of the medicinal materials, and carry out water extraction and alcohol precipitation of the crude products of some medicinal materials, which have low active ingredient content, large dosage, incomplete absorption, biological Inadequacies such as low utilization

With the continuous development of science and technology and the continuous improvement of the level of new drug research and development, the continuous application of new theories, new technologies, new processes, and new equipment, its traditional preparation process does not fully meet the requirements of modernization of traditional Chinese medicine.

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