Drug for treating diabetes-related complications and preparation method of drug

Abstract

The invention discloses a medicine for treating diabetes-related complications and a preparation method thereof. The agonist cinnamon aldehyde of TRAP1 has a potential protective effect on diabetic cardiomyopathy, and at the same time, it can lower blood pressure and improve blood vessel function; it can resist platelet aggregation and prevent thrombus formation; Viral myocarditis damages the heart; improves glucose and lipid metabolism, has good effects and few side effects, and the drug plays a protective role against the main mechanism of diabetic cardiomyopathy, bringing a new treatment strategy for the treatment of diabetic cardiomyopathy; at the same time It solves the disadvantage of the current drug treatment of diabetes-related complications, that is, the side effects are large, and the situation that patients stop drug treatment because they cannot tolerate the side effects of the drug. Experiments have proved that cinnamon aldehyde can exert a potential protective effect on diabetic cardiomyopathy by stimulating TRAP1 receptors, so TRAP1 agonists have brought new dawn for the treatment of diabetic cardiomyopathy.

Description

technical field [0001] The invention belongs to the technical field of clinical medicine, and in particular relates to a medicine for treating diabetes-related complications and a preparation method thereof. Background technique [0002] Diabetes is a major disease that affects the health of Chinese people. At present, there are more than 100 million diabetic patients in my country. Diabetic cardiomyopathy is its main complication. The Framingham study, the UK Prospective Diabetes Study (UKPDS), the Cardiovascular Health Study (CHS), and the European Heart Failure Survey (EHFSⅡ) have all confirmed that the proportion of heart failure in diabetic patients is increasing year by year. UKPDS research shows that among diabetic patients, 2.3% to 11.9% of them develop heart failure. The EHFSⅡ study found that 32.8% of heart failure patients were caused by diabetes. It can be seen that diabetes is closely related to the occurrence of heart failure. It is of great strategic signifi...

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Problems solved by technology

[0004] The purpose of the present invention is to provide a drug for treating diabetes-related complications and its preparation method, aiming to solve the disadvantages of current drug treatment for diabetes-related complications, that is, large side effects, and the problem that patients stop treatment because they cannot tolerate the side effects of drugs

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