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Drug mixing and delivery system and method

A technology of mixtures and medicaments, applied in botany equipment and methods, drug combinations, drug delivery, etc., can solve the problem that drugs do not have the recommended efficacy for anaphylactic shock

Inactive Publication Date: 2016-10-26
WINDGAP MEDICAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Failure to do so could allow the agent to degrade rapidly and render the drug less effective than recommended for anaphylactic shock episodes

Method used

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  • Drug mixing and delivery system and method
  • Drug mixing and delivery system and method
  • Drug mixing and delivery system and method

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Embodiment Construction

[0036] Provided herein are methods of preparing medical solutions containing therapeutic agents. In some embodiments, some aspects of the present invention involve preparing a dry pharmaceutical composition (e.g., dry salt form) to stabilize the drug and make the drug less prone to temperature-induced degradation, which can be easily reconstituted (e.g., , In the case of autoinjectors) for delivery to the patient.

[0037] The dry composition can be prepared by any suitable method as used in pharmaceutical formulations. For example, the drug may be chemically derived, lyophilized (freeze-dried), and / or spray-dried, and / or used any other technique to make the drug and / or medicament into a dry form. However, in some embodiments, it is important that the dried drug can be easily and quickly dissolved so that the dry composition can be used in an autoinjector that also contains a liquid component that can be activated after the autoinjector (e.g., , Before injection or during injec...

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Abstract

The present disclosure provides methods of preparing a medical solution. In some aspects, the medical solution can be prepared from mixing a first liquid with a second liquid or mixing a solid component with a liquid in an autoinjector. In some aspects, the heat released from the mixing can promote solubility of a dry medicament in the solution.

Description

[0001] Related application [0002] According to 35 USC §119(e), the present invention is based on the priority of the U.S. Provisional Patent Application USSN61 / 917,925 filed on December 18, 2013 and the United States Provisional Patent Application USSN62 / 016,260 filed on June 24, 2014. Priority, their respective entire contents are incorporated herein by reference. Background technique [0003] Individuals suffering from certain medical conditions often need to store auto-injectors or pre-filled syringes nearby to meet medical needs. Some examples of such auto-injectors or pre-filled syringes are insulin pens for diabetic patients, epinephrine auto-injectors for food and insect bite allergy patients, and at risk of exposure to field chemical and / or biological toxins Antidote for the soldiers. [0004] Exposure to certain substances (such as, for example, peanuts, shellfish, bee venom, certain drugs, toxins, etc.) can cause allergic reactions in sensitive individuals. This allerg...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N33/24
CPCA61K31/137A61K38/00A61K45/06A61K31/4045A61K9/0019A61M5/19A61M5/2046A61M5/3294A61M5/44A61M2205/364A61M2205/366A61M5/1409A61K38/26A61P25/06A61P3/08A61P9/02A61M5/2448A61M5/284
Inventor 布兰特·A·布钦内亚当·R·斯坦德利克里斯托弗·J·斯捷潘尼扬
Owner WINDGAP MEDICAL