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Preparation method of hydrophilic coating for medical catheter

A technology for medical catheters and hydrophilic coatings, applied in the direction of catheters, coatings, pharmaceutical formulations, etc., can solve problems such as unreachable and toxic effects on the human body, and achieve good effects, good lubricating effects, and low cost

Inactive Publication Date: 2016-12-07
四川一众药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The hydrophilic substance has good hydrophilicity and has a good lubricating effect, but the hydrophilic substance cannot meet the requirements of medical equipment due to its own material characteristics, such as toxic effects on the human body, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1: The present invention provides a kind of preparation method of hydrophilic coating for medical catheter, it is characterized in that, comprises steps:

[0015] a. preparing a coating solution with a solids content of 5%, said coating solution comprising an aqueous dispersion of urethane with a solids content of 46% and a polysiloxane or silicone emulsion with a solids content of 19%;

[0016] b. adding a high molecular polymer or monomer solution with a hydrophilic group in the coating solution, the volume ratio of the high molecular polymer or monomer solution with a hydrophilic group to the coating solution is 1 :3;

[0017] c. adding a crosslinking agent to the solution obtained in step b, stirring evenly to form a hydrophilic coating solution;

[0018] d. Coating the hydrophilic coating solution in step c on the surface of the medical catheter, so that the hydrophilic coating is solidified into a thin layer on the catheter surface.

[0019] Add 2.5ml...

Embodiment 2

[0022] Embodiment two: a kind of preparation method of hydrophilic coating for medical catheter, comprises steps:

[0023] a. preparing a coating solution with a solids content of 25%, said coating solution comprising an aqueous dispersion of 36% solids content of urethane and a polysiloxane or silicone emulsion with a solids content of 19%;

[0024] b. adding a high molecular polymer or monomer solution with a hydrophilic group in the coating solution, the volume ratio of the high molecular polymer or monomer solution with a hydrophilic group to the coating solution is 1 :3;

[0025] c. adding a crosslinking agent to the solution obtained in step b, stirring evenly to form a hydrophilic coating solution;

[0026] d. Coating the hydrophilic coating solution in step c on the surface of the medical catheter, so that the hydrophilic coating is solidified into a thin layer on the catheter surface. Add 4 ml of cross-linking agent per 100 ml of the solution obtained in step b. In...

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Abstract

The present invention relates to the technical field of preparation methods, and discloses a method for preparing a hydrophilic coating for medical catheters, comprising the steps of: a. preparing a coating solution with a solid content of 5%-25%, the coating solution comprising a solid content of 36% %-46% aqueous dispersion of urethane and a polysiloxane or siloxane emulsion with a solid content of 19%; b. adding a high molecular polymer with a hydrophilic group in the coating solution Or a monomer solution, the volume ratio of the high molecular polymer or monomer solution with a hydrophilic group to the coating solution is 1:3; c. add a crosslinking agent to the solution obtained in step b, and stir uniform; d. coating the hydrophilic coating solution in step c on the surface of the medical catheter, so that the hydrophilic coating solidifies into a thin layer on the catheter surface. The method is simple, low in cost and good in effect, and the prepared hydrophilic coating has good hydrophilic performance, is nontoxic and harmless, and is well bonded to catheters.

Description

technical field [0001] The invention relates to the technical field of preparation methods, in particular to a preparation method of a hydrophilic coating for medical catheters. Background technique [0002] Urinary catheters and gastric tubes are commonly used insertion medical devices. Since they need to be inserted into the patient's body, there are high requirements for the softness and comfort of their surfaces. The hydrophilic substance has good hydrophilicity and has a good lubricating effect, but the hydrophilic substance cannot meet the requirements of medical equipment due to some material characteristics of itself, such as poisonous effects on the human body. [0003] Therefore, it is an urgent problem to be solved by those skilled in the art to study a method for preparing a hydrophilic coating for medical catheters, so as to improve the comfort of patients using the catheter and eliminate the side effects of the hydrophilic coating. Contents of the invention ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L29/14A61L29/08
CPCA61L29/14A61L29/08A61L29/085A61L2400/10A61L2420/02A61L2420/06
Inventor 马英祥
Owner 四川一众药业有限公司
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