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Glaucoma early stage screening method

A glaucoma and screening technology, applied in the field of medical image data processing, can solve the problems of high price of inspection instruments, large errors, and high prevalence of glaucoma

Inactive Publication Date: 2016-12-14
靳晓亮 +2
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0010] (2) Standardized automatic visual field: Although the inspection is the gold standard for assessing glaucoma functional impairment, it is a subjective inspection, which relies on the cooperation of the subjects and takes a long time (the current SITA-Fast and TOP inspection procedures are still not short enough, and each eye It takes at least a few minutes for the inspection), and the low penetration rate of the perimetry at the grassroots level, and its large size is not easy to carry, which limits its large-scale grassroots population screening
[0012] (4) Direct ophthalmoscopy: the evaluation of the optic nerve has the advantages of rapidity and economy, but its sensitivity and specificity are low, the error is relatively large due to the quality of medical personnel, and the lack of objective records is not conducive to consultation and database establishment
[0013] (5) Examination of optic nerve quantitative measuring instruments such as HRT, GDX, OCT, etc.: it takes a long time, the inspection equipment is expensive, the penetration rate at the grassroots level is very low, the professional requirements of the inspectors are high, and the result interpretation requires specific professional knowledge, etc., screening for most people check is not useful
However, the use of simple measuring instruments to measure cups and plates is more complicated than the operation, and requires high professional requirements and clinical experience for inspectors, while the use of complex measuring instruments is expensive, neither of which can be effectively promoted in primary medical institutions
Medical research in my country has confirmed that the current prevalence of glaucoma in the Chinese population is high and the efficiency of diagnosis and treatment is low. The screening system is very important

Method used

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Embodiment Construction

[0082] Embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings. The fundus imaging device used in this embodiment is Canon CR-DGi (non-mydriatic fundus camera), and the software used is MATLAB, such as figure 2As shown in the flowchart of the glaucoma screening method of the present invention, the following steps are performed.

[0083] Step 1, through the fundus imaging equipment to obtain such as image 3 and Figure 4 The original fundus photos of the left and right eyes in the RGB color mode shown are input into the computer;

[0084] Step 2, perform HSV color mode conversion on the original fundus photo, and extract the brightness parameter V, and obtain the following: Figure 5 and Figure 6 The left and right eye fundus brightness grayscale images are shown;

[0085] Step 3, binarize the fundus brightness grayscale image to form Figure 7 and Figure 8 The black and white two-color binarized grayscale i...

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Abstract

The invention relates to a glaucoma early stage screening method using a computer to carry out automatic analysis for eyeground photographs, thus fast calculating an eye cup-eye disk C / D ratio value in real time; the features are that the C / D value is compared with a set glaucoma risk value so as to determine the glaucoma existence possibility. The advantages are that the cup / disk ratio changes formed by glaucoma pathology optic nerve progressive damages are employed, thus carrying out automatic eyeground photograph reading analysis under computer assistance. Image fuzzy processing, OTSU algorithm and computer operation are introduced so as to greatly improve determination result accuracy and instantaneity when compared with a conventional diagnosis method singly using an eyeground photograph reading mode, and avoiding expensive and complex detection equipment; low cost high efficiency screening method can be carried out so as to realize glaucoma early discovery and early diagnosis; a database is built, and a screening and uploading step by step mode is employed, thus gradually improving a big data development system under a three-level networking system.

Description

technical field [0001] The invention relates to an early screening method for glaucoma, which relates to the technical field of medical image data processing. technical background [0002] Glaucoma is one of the three leading causes of blindness in the world and is an important global public health problem. Long-term optic nerve damage will eventually lead to irreversible blindness, causing heavy pressure and burden on the patient himself, his family and the society. [0003] China is a country with a large number of glaucoma patients, and there is a long way to go to prevent and treat glaucoma. According to the World Health Organization (WHO), the number of patients with primary glaucoma in China in 2010 was about 15.78 million (11.11-23.64 million), of which 8.31 million (6.70 million-10.42 million) were primary open-angle glaucoma (POAG). , accounting for 18.6% of global POAG; primary angle-closure glaucoma (PACG) was 7.47 million (4.42 million to 13.22 million), account...

Claims

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Application Information

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IPC IPC(8): A61B3/16A61B3/12
CPCA61B3/165A61B3/0016A61B3/12
Inventor 靳晓亮盛波吴屹俊
Owner 靳晓亮
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