Large animal spinal cord instant impact damage model modeling striking machine

Abstract

The invention discloses a large animal spinal cord instant impact damage model modeling striking machine which comprises a base. The base is provided with a plurality of struts and a plurality of adjusting nuts. The struts are provided with upper connecting plates, and the connecting plates are provided with screw rods and a plurality of guide posts. The screw rods and the guide posts are fixedly connected with a horizontal adjustment device. The screw rods are slidably connected with a counter arranged above the horizontal adjustment device, and the screw rods are fixedly connected with a hand wheel arranged above the counter. The screw rods are further slidably connected with a sliding plate arranged below the horizontal adjustment device, the sliding plate is fixedly connected with a fixing connecting rod, the fixing connecting rod is rotatably connected with a translation connecting rod, the translation connecting rod is rotatably connected with a plane fine adjustment device, and the plane fine adjustment device is provided with an aiming striking device. Standardized operation makes experiment repeatability higher, the large animal spinal cord instant impact damage model modeling striking machine is suitable for manufacturing various large experimental animal spinal cord impact damage models and meets laboratory requirements, the models can be produced in batches, and the large animal spinal cord instant impact damage model modeling striking machine has good scientific research values and social economic values.

Description

technical field [0001] The invention relates to the technical field of animal experiment equipment, in particular to a modeling striker for modeling the spinal cord instantaneous impact injury model of a large animal. Background technique [0002] The incidence of spinal cord injury is increasing year by year and the disability rate is very high, which seriously affects the health, function and quality of life of patients, and brings a heavy economic burden to society and families. At present, a lot of research on spinal cord injury has been carried out, but the research on the pathological mechanisms such as hemorrhage, swelling, tissue liquefaction necrosis, calcification, and nerve regeneration after spinal cord injury has yet to be broken through, and the prognosis is still very poor. Therefore, the treatment of spinal cord injury has become a difficult task. The chasm was crossed. [0003] In order to find a way to treat spinal cord injury, a large number of experiment...

AI Technical Summary

Problems solved by technology

The reported spinal cord injury model methods used in large animal spinal cord injury research include the hemostat clamp method spinal cord crush injury model, the heavy object drop method spinal cord injury model, etc. The spinal cord crush injury model uses a hemostat to clamp the animal Spinal cord, there is insufficient clamping time and force can not be accurately controlled, which will cause great variability in the degree of spinal cord injury, and there is a large gap between the crush injury model and the actual clinical situation (because the clinical spinal cord injury mechanism is mostly Spinal cord contusion rather than crush injury), in order to ensure the scientific nature of the research, the spinal cord instantaneous impact injury model should be used; the heavy object falling method spinal cord injury model reported in the current large animal research has poor equipment and cannot guarantee the standardization of the spinal cord injury model , precision and repeatability

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