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Usage of protopanaxatriol in preparing medicine for preventing and treating telangiectasis

A technology of telangiectasia and protopanaxatriol, which is applied in the field of biomedicine, can solve problems such as capillary tolerance excess, telangiectasia rupture, and poor blood circulation, and achieve the effect of inhibiting telangiectasia

Active Publication Date: 2017-01-25
SHAANXI GIANT BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] (3) Environmental factors: frostbite is likely to occur in alpine regions, resulting in poor blood circulation, stasis of blood vessel walls, and spider web-like red blood streaks on the face; cold stimulation, dry air, windy and sandy climate, and sun exposure make the capillary tolerance exceed Normal range, causing rupture of telangiectasia

Method used

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  • Usage of protopanaxatriol in preparing medicine for preventing and treating telangiectasis
  • Usage of protopanaxatriol in preparing medicine for preventing and treating telangiectasis
  • Usage of protopanaxatriol in preparing medicine for preventing and treating telangiectasis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Embodiment 1 protopanaxatriol (PPT) ointment

[0040] Make ointment according to the following ratio (100 tubes, 10g / tube, protopanaxatriol (PPT) content 100mg / tube)

[0041]

[0042] The main process flow is as follows: First add glycerin and 1,3-butanediol into the vacuum emulsification tank, raise the temperature to 70°C, and stir at a speed of 150rpm, then add methylparaben, propylparaben, and stearyl alcohol in sequence , glyceryl monostearate, petrolatum and lanolin, adjust the speed to 300rpm, stir for 15min, then cool down to 50°C, add protopanaxatriol (PPT) and continue stirring for 20min, then adjust the vacuum speed to 3000rpm and stir for 15min to complete the emulsification , cooled to room temperature and filled. The net content is about 10g / tube, and the protopanaxatriol (PPT) content is 100mg / tube.

Embodiment 2

[0043] Embodiment 2 protopanaxatriol (PPT) gel

[0044] Make a gel according to the following ratio (100 tubes, 20g / tube, protopanaxatriol (PPT) content 250mg / tube)

[0045]

[0046]

[0047] Take Carbomer 941, add a small amount of water to swell in the preparation tank. Stir and dissolve protopanaxatriol (PPT) with ethanol, then add propylene glycol and glycerin in sequence, slowly add this solution into the carbomer matrix, stir while adding, then add triethanolamine dropwise, and finally add purified water to 2000g, stir Evenly, the translucent protopanaxatriol (PPT) gel is obtained.

Embodiment 3

[0048] Embodiment 3 takes protopanaxatriol (PPT) as the therapeutic effect of the pharmaceutical composition of active ingredient on telangiectasia

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Abstract

The invention relates to the usage of protopanaxatriol in preparing a medicine for preventing and treating telangiectasis. The invention further provides a medicine composition used for curing or preventing telangiectasis. The medicine composition comprises the effective dose of protopanaxatriol taken as an active component for curing or preventing, and a pharmaceutically acceptable carrier.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to the application of protopanaxatriol (PPT) in treating or preventing telangiectasia. Background technique [0002] Telangiectasia, commonly known as red blood, is mainly due to the weakening of the facial cuticle, which makes the facial capillaries easier to contact and perceive changes in the external environment, resulting in redness of the face, especially the cheeks, caused by telangiectasia. Patients with facial redness have a redder or purplish red appearance than normal skin tone. People often call it plateau face or red face. Most of them are red on both sides of the cheeks, with round borders and generally arranged in silk threads. This kind of skin is thin and sensitive, and it has obvious reactions to cold, heat, and emotional agitation. This kind of reaction affects the appearance, and it will also cause psychological shadows to patients and bring a lot of inconvenience to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/575A61P17/00A61P9/14
CPCA61K31/575
Inventor 范代娣段志广马晓轩黄蓉范翠英刘彦楠严建亚
Owner SHAANXI GIANT BIOTECHNOLOGY CO LTD