Atomizing type medicinal collagen dressing and preparing method thereof
A collagen and sticking technology, applied in the field of biomedicine, can solve the problems of increasing the difficulty of patients, inconvenient for patients to use and carry, and unfavorable for patients to carry around, so as to achieve the effects of convenient carrying, promoting wound healing, and improving compliance
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[0039] The raw materials for the preparation of the collagen solution include 0.01-0.5 parts by mass of collagen, preferably 0.05-0.45 parts by mass, more preferably 0.10-0.30 parts by mass. The collagen is preferably human-like collagen, bovine-derived collagen, porcine-derived collagen or fish-derived collagen.
[0040] The raw materials for preparing the collagen solution in the present invention further include 82.5-96.89 parts by mass of water, preferably 85-95 parts by mass, more preferably 87-92 parts by mass. The water is preferably purified water.
[0041] The raw materials for the preparation of the collagen solution in the present invention further include 3-15 parts by mass of glycerin, preferably 5-12 parts by mass, more preferably 8-10 parts by mass. The glycerin is medical glycerin.
[0042] The raw materials for the preparation of the collagen solution in the present invention further include 0.1-2 parts by mass of glutaraldehyde, preferably 0.5-1.5 parts by ...
Embodiment 1
[0061] 1. Formula of collagen solution:
[0062]
[0063] 2. Preparation process of spray-type medical collagen dressing
[0064]Mix medical glycerin, purified water and a pH regulator to obtain a mixed solution with a pH of 4-6, add bovine-derived collagen to the mixed solution, and mix and stir at a temperature of 20-25°C until The collagen is completely dissolved to obtain a collagen solution. The collagen solution is mixed with glutaraldehyde to obtain a collagen solution.
[0065] The collagen solution is filled in the 1.5ml medical polyethylene spray bottle, and the cap is twisted to obtain the product. The obtained product is sterilized by irradiation.
[0066] The spray-type medical collagen plaster dressing prepared above was sprayed, and the amount of collagen solution and the film-forming time were measured. The results are shown in Table 1, and Table 1 shows the dosage of the product collagen solution and the film-forming time.
[0067] Table 1 Collagen sol...
Embodiment 2
[0070] 1. Formula of collagen solution:
[0071]
[0072] 2. Preparation process of spray-type medical collagen dressing
[0073] Mix medical glycerin, purified water and a pH regulator to obtain a mixed solution with a pH of 4-6, add collagen to the mixed solution, and mix and stir at a temperature of 20-25°C until the collagen is completely Dissolved to obtain a collagen solution. The collagen solution is mixed with glutaraldehyde to obtain a collagen solution.
[0074] The collagen solution is filled in the 10ml medical polyethylene spray bottle, and the cap is twisted to obtain the product. The obtained product is sterilized by irradiation.
[0075] The spray-type medical collagen plaster dressing prepared above was sprayed, and the amount of collagen solution and the film-forming time were measured. The results are shown in Table 1, and Table 1 shows the dosage of the product collagen solution and the film-forming time.
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