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Long-acting high-definition intensified radiography method for CT of tiny animal

An animal, tiny technology, applied in the field of medical imaging, can solve the problems of slow scanning time, poor imaging, and blood vessel burst damage, and achieve the effect of improving work efficiency, reducing operating costs, and improving image quality

Inactive Publication Date: 2017-03-15
朱亚新
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] MCI and CT are relatively advanced medical scanning inspection equipment, but the current MCI and CT are mostly single-row ct, and the scanning time is extremely slow. The short-acting contrast agent sold on the market cannot enter the bladder quickly, and cannot perform long-term high-definition whole body development
Long-acting contrast agents are often used for long-term angiography in animals. Long-acting contrast agents are generally made of nano-gold ion materials, which are difficult to prepare and extremely expensive. At present, the injection of contrast agents in small animals uses a single tail vein cannula. The venous catheter is extremely difficult to fix, the drug injection flow rate is not good, the tail vein is far from the proximal end, the imaging is not good, and the high-pressure injection can easily cause blood vessel burst damage

Method used

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Embodiment Construction

[0007] A long-acting high-definition enhanced contrast method for micro-animal CT, which uses iodine contrast agent instead of nano-gold ion contrast agent, and injects contrast technology through dual channels. Tail phlebotomy and puncture were performed with a trocar, and iodine contrast agent was injected into the tail vein by dripping with an intravenous syringe.

[0008] The dual-channel injection of the contrast agent in the method of the present invention can not only greatly increase the image quality, but also improve the working efficiency of micro-animal imaging. The cost of the iodine contrast agent is very cheap, and the operation cost is greatly reduced. The adverse reactions of contrast agents and the impact on experimental individuals after use have undergone long-term clinical evaluation, but the adverse reactions of gold nanoparticle contrast agents have not been evaluated for a long time, and gold nanoparticles will pollute the environment and are extremely e...

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PUM

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Abstract

Provided is a long-acting high-definition intensified radiography method for CT of a tiny animal. The method adopts the radiography technology of the replacement of a nanometer gold ion contrast agent with diodone and dual-channel injection. The method comprises the steps of firstly, using an anesthesia pump to make the tiny animal inhale isoflurane air and under narcotism, conducting rump vein cutting paracentesis with a 24 g trocar, injecting diodone to the rump vein by using intravenous injector infusion, meanwhile, adopting the deep cervical vein to cut the jugular vein intubation, and adopting a injection pump to inject diodone. By injecting the contrast agent through dual channels, the long-acting high-definition intensified radiography method for CT of the tiny animal not only drastically improves the image quality, but also improves the efficiency of tiny animal radiography work. The cost of diodone is very low, and the operation cost reduces greatly. Diodone, used in the long term in the market, is adopted, the untoward effects of the contrast agent and the influence on experimental individuals after usage have gone through long-term clinical assessment, however, the untoward effects of the nanometer gold ion contrast agent have not gone through long-term assessment, the nanometer gold ions can pollute the environment, and the price of the nanometer gold ions is high.

Description

technical field [0001] The invention relates to the technical field of medical imaging, in particular to a long-acting high-definition enhanced imaging method for micro-animal CT. Background technique [0002] MCI and CT are relatively advanced medical scanning inspection equipment, but the current MCI and CT are mostly single-row ct, and the scanning time is extremely slow. The short-acting contrast agent sold on the market cannot enter the bladder quickly, and cannot perform long-term high-definition whole body development. Long-acting contrast agents are often used for long-term angiography in animals. Long-acting contrast agents are generally made of nano-gold ion materials, which are difficult to prepare and extremely expensive. At present, the injection of contrast agents in small animals uses a single tail vein cannula. The venous cannula is extremely difficult to fix, the drug injection flow rate is not good, the tail vein is far from the proximal end, the imaging i...

Claims

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Application Information

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IPC IPC(8): A61D7/00A61B6/03
CPCA61D7/00A61B6/032A61B6/508
Inventor 朱亚新
Owner 朱亚新
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