26 results about "Animal imaging" patented technology

The invention relates to the technical field of small animal imaging, and particularly discloses a bimodal small animal molecular image imaging device which comprises a rack; the rotating bracket is rotationally mounted on the rack; the rotating assembly is installed on the rack and used for driving the rotating support to rotate relative to the rack; the CT imaging assembly is mounted on one side of the rotating bracket; the SPECT imaging assembly is installed on the other side of the rotating support, and the imaging center of the SPECT imaging assembly and the imaging center of the CT imaging assembly are coaxial with the rotating axis of the rotating support; the animal bed assembly is installed on the rack and used for bearing a small animal to be imaged and driving the small animal to be imaged to move towards or away from the rotating support along the rotating shaft of the rotating support; the method can effectively solve the problems of registration error, attenuation correction failure, image fusion quality reduction and quantitative analysis misalignment when the SPECT image and the CT image are fused due to alignment error of the SPECT imaging assembly and the CT imaging assembly.

The embodiment of the invention discloses a method and system for emission computed tomography for animal imaging. The method comprises the steps that a plurality of imaging animals are placed on a plurality of trays in preset placement postures, each tray is configured to place one imaging animal, each tray comprises a body part fixing part, and the body part fixing parts are configured to fix the preset placement postures of the imaging animals placed on the body part fixing parts; placing a plurality of trays on the supporting part of the multi-imaging animal fixing device; the multi-imaging-animal fixing device is placed in an animal cabin of scanning equipment, and emission computed tomography is carried out on multiple imaging animals at the same time.

The application relates to an animal cage and an animal imaging system. The animal cage is used for carrying an animal to be scanned into a scanning channel, one end of the animal cage is connected with a scanning bed, and the other end is provided with a stabilizing assembly. The stabilizing assembly comprises a base, a driving member and a plurality of supporting members. The base is fixedly arranged on the animal cage. The supporting members are slidingly connected along the radial direction of the base, and the supporting members are uniformly distributed along the circumferential direction of the base. The driving member is arranged on the base and is movably connected with each supporting member, and is used for driving each supporting member to synchronously slide along the radial direction of the base. When each supporting member is expanded, the stabilizing assembly can abut against and press the inner wall of the scanning channel, can finely adjust the animal cage, can improve the coincidence degree of the axis of the animal cage and the axis of the scanning channel, and can center the animal cage.

The utility model belongs to the technical field of nuclear medicine imaging, and discloses a cooling module and animal imaging equipment, the cooling module is used for cooling a probe module of the animal imaging equipment, the cooling module comprises a cooling base, a cooling main body and a control panel, the cooling base is provided with a first cooling cavity and is used for supporting and cooling a mainboard of the probe module, and the control panel is provided with a second cooling cavity. One end of the cooling body is connected with the side, away from the probe module, of the cooling base, a second cooling cavity is formed in the cooling body, and the control panel is attached to the surface of the cooling body and electrically connected with a mainboard of the probe module. The cooling module has a good heat dissipation effect on the probe module, and can timely dissipate heat generated when the mainboard of the probe module and the control panel of the equipment work, so that the imaging precision is ensured, and the service life of the probe module is prolonged.

The temperature and humidity three-control image cabin for animal imaging comprises a cabin body, a temperature and humidity sensor is arranged on the side wall of the cabin body, and the temperature and humidity in the cabin body are monitored in real time; when the temperature in the cabin body is lower than a set value, an electric heating pipe is started, airflow sequentially passes through a second through groove in the upper end of a baffle and a second through groove in the lower end of the side wall, away from one side of the baffle, of a second cavity, and hot air enters the cabin body from the bottom; when the temperature in the cabin body is higher than a set value, the cooling water pipe is communicated with an external cold source, and airflow sequentially passes through a second through groove in the lower end of the baffle and a second through groove in the upper end of the side wall of the side, away from the baffle, of the second cavity and enters the cabin body from the upper portion; hot air and cold air respectively enter the cabin body from the bottom and the upper part of the cabin body and are matched with the density of the hot air and the density of the cold air, so that air in the cabin body flows more smoothly, and the temperature in the cabin body is effectively adjusted; in addition, the contact time of air and spray is prolonged, and the humidifying effect is better.

The embodiment of the invention discloses a multi-imaging animal fixing device, a tray, an animal cabin and an animal imaging system. The multi-imaging animal fixing device comprises a supporting part and trays, wherein the supporting part is configured to support the trays; and the tray is detachably connected with the supporting part. The tray comprises a first end part, the first end part is configured to place the head of an imaging animal, each tray is provided with a detachably connected marker accommodating part, the marker accommodating part is configured to accommodate a marker, and the marker can be developed in an imaging mode of at least one mode.

1. The name of the design product: animal live imaging instrument. 2. The use of the design product: for live small animal imaging. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

The utility model belongs to the technical field of nuclear medicine imaging, and discloses a probe module and animal imaging equipment, the probe module comprises a main board, a protective cover and a fixing structural member, the main board is provided with a plurality of probe units, the protective cover is provided with an opening side, the protective cover and the main board define a protective cavity, the plurality of probe units are located in the protective cavity, and the fixing structural member is located in the protective cavity. The fixing structural member is arranged on the side, away from the probe unit, of the main board and connected with the opening side, and the fixing structural member is used for fixing the probe module to the cooling base. The probe module is easy to assemble and convenient to install, the protective cover is not prone to deformation, and the protection and shielding effects on the probe unit are good.

The utility model relates to the technical field of anti-radiation protection devices, in particular to an anti-radiation protection device with a fixing structure for animal iconography, which comprises a main body, a body position fixing device for fixing an experimental animal is arranged in the main body, and the body position fixing device comprises two groups of identical fixing devices. The fixing device comprises two fixing branch devices which are arranged in a staggered mode, a fixing groove is formed in the bottom of the operation cabin, the fixing branch devices are installed in the fixing groove in a sliding mode to adjust the distance, and each fixing branch device comprises a fixing plate and further comprises an arc-shaped clamping position. The arc-shaped clamping positions are installed in the fixing plate in a sliding mode so that the height can be adjusted to fix animals of different postures, experimental animals of different postures can be fixed in a matched mode by adjusting the staggered distance between the two fixing branch devices and the height of the arc-shaped clamping positions, the animals can be effectively fixed, and it can be prevented that the animals move disorderly to affect an experiment, and air bags are further arranged on the arc-shaped clamping positions. Therefore, the body type of the experimental animal can be better fitted, and the discomfort of the experimental animal in the examination process is reduced.

1. The name of the design product: medical animal imaging equipment (separate shielding PET-SPECT-CT). 2. The use of the design product: for medical imaging. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

1. Name of the product of this design: Photoacoustic ultrasound imager for animal imaging. 2. Purpose of the product of this design: A device or instrument used for photoacoustic ultrasound imaging of animal or biological tissues. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The embodiment of the invention discloses an animal imaging method and system. The method comprises the following steps: acquiring a first medical image of an imaging animal acquired by first scanning equipment in first scanning; acquiring a second medical image of the imaging animal acquired by second scanning equipment in second scanning; and performing registration fusion on the first medical image and the second medical image to generate a target medical image of the imaging animal. Wherein in the first scanning and the second scanning, the imaging animal is placed on the tray in a preset placement posture and is respectively placed in the first scanning equipment and the second scanning equipment through the tray, and a marker accommodating part is arranged on the tray and is configured to accommodate developable markers in the first medical image and the second medical image; registration fusion is performed based on markers in the first medical image and the second medical image.

This invention relates to the interdisciplinary field of biomedicine and molecular imaging, specifically a novel magnetic resonance imaging contrast agent, its preparation method, and its application. The contrast agent uses thymosin α1 as the parent compound, linked with three identical substituents R, where R are metal chelate groups. These metal chelate groups are formed by coordination of a chelating agent and a metal ion; the chelating agent can be diethylenetriaminepentaacetic acid, etc., and the metal ion can be selected from gadolinium, manganese, and iron. The preparation method of the contrast agent includes: activating the chelating agent and grafting it onto thymosin α1 to form a chelate precursor; and coordinating the chelate precursor with a metal ion. The contrast agent prepared by this invention exhibits a significant T1 enhancement effect, lymphoselectivity, and reduced concomitant venous contamination; detection results show that it has excellent lymphatic system visualization capabilities in in vivo animal imaging, providing a prospective reference for replacing existing contrast agents.

The invention discloses a special X-ray cone-beam computed tomography system for animals with a double-image system, and relates to the technical field of cone-beam computed tomography. Comprising an internal rotary supporting structure, a detachable bed board, a large animal imaging module, a small animal imaging module and a control module. The large animal imaging module and the small animal imaging module are coaxially installed on the rotating rack and share the same electrical system and imaging control logic. Through the design of a dual-module coaxial rotation imaging structure, high and low power imaging modules adapted to animals with different body types and a detachable low-attenuation bed board, the comprehensive improvement of the animal imaging system in resolution, application range and imaging stability is realized.

The utility model provides an objective lens light shield for living animal imaging, which comprises a first light shield and a second light shield, the first light shield is arranged on an objective lens, and the window of the first light shield is larger than the lens diameter of the objective lens; the second light shield is arranged on an animal to be imaged, and a window of the second light shield is larger than an imaging part of the animal; the shape of one end of the first light shield away from the objective lens is matched with the shape of one end of the second light shield away from the to-be-imaged animal. According to the utility model, through cooperation of the two shading structures, external screen light cannot enter the objective lens, so that imaging quality is ensured, and the problems that screen light in imaging is collected through the objective lens and enters a microscope detector, image quality is affected and even the light intensity upper limit bearable by the detector is exceeded, and imaging quality is affected are solved. And normal imaging cannot be carried out.

The present application relates to a kind of self-interference digital holographic imaging systems based on birefringent crystal lens.By using incoherent light source illumination to remove the influence of laser speckle on image quality caused by laser illumination, the imaging quality is improved. By the combination of the polarization characteristics of alpha-BBO birefringent crystal lens, quarter-wave plate and polarization camera, single-shot imaging and fast imaging are realized. The present application overcomes the problem of image degradation caused by laser speckle and the safety hazard caused by using laser illumination for human face and animal imaging, solves the problem of optical path difference compensation in coaxial optical path under incoherent illumination, and realizes the need for large field of view color 3D imaging of daily objects.

1. The name of the design product: animal image inspection graphical user interface for electronic equipment. 2. The use of the design product: for an electronic device. 3. The design points of the design product: in the graphical user interface. 4. The picture or photo that best indicates the design points: front view. 5. The electronic equipment is a conventional design, and other views are omitted. 6. The use of the graphical user interface: for editing, modifying and displaying experimental parameters of animal imaging equipment (such as MicroPET-CT); enter the interface change state diagram by selecting the "arrow" at the right angle of the main view interface.

The present invention provides a liquid helium-free superconducting magnet for animal imaging, comprising a superconducting magnet, a liquid helium-free cryogenic system, and a pull rod. The superconducting magnet comprises a main magnet, a shielding magnet, and a 4K container. The main coil is wound within the external wire slots of the main frame to form the main magnet, the shielding coil is wound within the external wire slots of the shielding frame to form the shielding magnet, and the 4K container contains the superconducting magnet. The liquid helium-free cryogenic system comprises a refrigerator, a first-stage cold head of the refrigerator, a cold shield, a second-stage cold head of the refrigerator, a cooling ring, a cooling belt, and a dewar container. The first-stage cold head of the refrigerator is directly connected to the cold shield to achieve first-stage cooling, the second-stage cold head of the refrigerator is directly connected to the cooling ring, and the cooling ring is connected to the shielding coil and the main coil via a cooling belt to achieve second-stage cooling of the superconducting magnet. The dewar container is used to create a vacuum environment for the cryogenic system. The superconducting magnet and the cold shield are suspended and fixed inside the dewar container by a pull rod to reduce contact heat leakage in the system. The diameter of the inner hole of the superconducting magnet is suitable for small animal imaging.

According to the near-infrared band multi-view three-dimensional fluorescence imaging device and method provided by the invention, on one hand, the excitation cavity on the inner wall of the plane mirror is combined with the divergent laser light source, a uniform excitation light field is formed through multiple reflections, and uniform excitation of medium and large samples is realized by using good penetrability of the near-infrared band; on the other hand, a multi-view fluorescence image is obtained through one-time imaging by utilizing the inner wall of the plane mirror of the excitation cavity and is used for three-dimensional fluorescence image reconstruction, and high-speed three-dimensional fluorescence imaging of medium and large samples, especially living animal imaging, is realized by integrating the two aspects. According to the invention, the system has visual angle synchronism: image data of multiple angles of an observed object can be obtained through single imaging, so that the problems of low efficiency and data asynchronization caused by time-sharing and manual body position adjustment are fundamentally avoided, and the system is based on a multi-visual-angle two-dimensional image set which is acquired at a time and consistent in space and time; and a complete data basis is provided for subsequently generating a high-precision three-dimensional model through a stereoscopic vision algorithm or a tomographic reconstruction algorithm.

The invention discloses a super-resolution network-based small animal CBCT (cone beam computed tomography) imaging device and a super-resolution network-based small animal CBCT imaging method with continuously adjustable FOV (field of view), both a radiation source and an objective table can horizontally move, and continuous adjustment of the FOV is realized through unique structural design and control mode. Meanwhile, the trained super-resolution network model is utilized to effectively optimize the image spatial resolution, and it is ensured that the system image resolution is not affected by the change of the FOV size. In an actual application scene, the equipment can flexibly adjust the size of an imaging visual field according to the size of an animal, keeps the high resolution of an image all the time, and breaks through the physical limit of conventional equipment hardware. Compared with the prior art, the method has remarkable advantages in the aspects of improving the flexibility and imaging quality of the imaging device, has extremely high practical value and innovativeness, and can be widely applied to the field of animal imaging.

1. Name of the designed product: medical animal imaging equipment (open bed PET). 2. Use of the designed product: for medical imaging. 3. Design points of the designed product: in shape. 4. Pictures or photos that best show the design points: perspective view.

1. Name of the designed product: medical animal imaging equipment (large field of view PET). 2. Use of the designed product: for medical imaging. 3. Design points of the designed product: in shape. 4. Pictures or photos that best show the design points: perspective view.

The application discloses a drawer type abdominal cavity window device and method for in-vivo kidney photoacoustic imaging, and belongs to the technical field of in-vivo animal imaging. The drawer type abdominal cavity window device for in-vivo kidney photoacoustic imaging comprises a titanium alloy fixing frame, an organ stabilizing system, a microenvironment maintaining system and a monitoring and control system. The titanium alloy fixing frame is internally provided with an anchoring structure for fixing with ribs of an experimental animal. The titanium alloy fixing frame is internally provided with a titanium alloy sliding inner frame. The titanium alloy sliding inner frame is symmetrically provided with sliding guide rails at two sides. The application realizes efficient transmission of sound waves through design of a composite acoustic window, solves the problem of sound wave attenuation caused by traditional glass materials, effectively suppresses organ motion artifacts through a drawer type structure and a negative pressure stabilizing system, supports long-term imaging through the microenvironment maintaining system, and provides a reliable technical platform for in-vivo kidney research.

The embodiment of the utility model discloses a multi-imaging animal fixing device, a tray, an animal cabin and an animal imaging system. The multi-imaging animal fixing device comprises a supporting part and trays, wherein the supporting part is configured to support the trays; and the tray is detachably connected with the supporting part. The tray comprises a first end part, the first end part is configured to place the head of an imaging animal, each tray is provided with a detachably connected marker accommodating part, the marker accommodating part is configured to accommodate a marker, and the marker can be developed in an imaging mode of at least one mode.

1. Name of the designed product: medical animal imaging equipment (closed bed PET). 2. Use of the designed product: for medical imaging. 3. Design points of the designed product: in shape. 4. Pictures or photos that best show the design points: perspective view.

The utility model belongs to the technical field of nuclear medicine imaging, and discloses a detection cabin and animal imaging equipment, the detection cabin is provided with two cabins, each cabin is used for loading an animal to be imaged, each cabin extends along the axial direction of the detection cabin, and the two cabins are arranged at intervals along the radial direction of the detection cabin. Each cabin is provided with a head cavity and a body cavity, and the head cavity is a gradually-expanded cavity with the width gradually increased; in the radial direction of the detection cabin, the head cavities of the two cabins are correspondingly arranged, the small end of one head cavity corresponds to the large end of the other head cavity, and the body cavities of the two cabins are arranged in a staggered mode. The transverse size of the detection cabin is relatively small, miniaturization design of the whole animal imaging equipment is facilitated, the two cabins in the detection cabin are not prone to interference in the imaging process, and the imaging precision and the imaging quality are improved.