40 results about "Animal imaging" patented technology

An apparatus for imaging an animal includes a first mounting surface, a bed sized to support the animal and releasably secured to or integral with the first mounting surface. The apparatus also includes a plurality of straps, each having a first end in a fixed position relative to the bed and a second end for tightening around a limb of the animal. A method for in-vivo imaging of an animal includes providing an animal that has limbs, providing a first mounting surface, and providing a bed removably secured to or integral with the mounting surface and sized to support the animal as well as being coupled to a plurality of straps. The method also includes placing the animal on the bed between the plurality of straps and tightening at least two of the plurality of straps around at least two of the limbs such that the animal is substantially secured in place relative to the bed.

An apparatus for imaging an animal includes a first mounting surface, a bed sized to support the animal and releasably secured to or integral with the first mounting surface. The apparatus also includes a plurality of straps, each having a first end in a fixed position relative to the bed and a second end for tightening around a limb of the animal. A method for in-vivo imaging of an animal includes providing an animal that has limbs, providing a first mounting surface, and providing a bed removably secured to or integral with the mounting surface and sized to support the animal as well as being coupled to a plurality of straps. The method also includes placing the animal on the bed between the plurality of straps and tightening at least two of the plurality of straps around at least two of the limbs such that the animal is substantially secured in place relative to the bed.

The invention facilitates transport of an immobilized, anesthetized small animal across multiple single-modality or multiple-modality imaging workstations at the same or different physical locations without loss of subject positional information. The animal holder is compatible with preclinical animal imaging stations such as micro-CT, micro-MR, micro-PET, micro-SPECT, and FMT. The animal holder is configured to be accommodated by (for example, fit within) individual imaging chambers of such instruments and is fabricated from materials that are compliant with all of the imaging modalities used. In certain embodiments, an integrated set of fiducial marker wells accommodates the dispensing of markers that are picked up by several modalities simultaneously in multiple planes. The fiducial markers then are aligned in standard image processing or image analysis software with simple image translation and rotation operations, without the need for more advanced scaling, distortion or other operations.

A device and a method for imaging an animal including an animal holding device for keeping the animal immobile and at a desired temperature during the scanning operation for imaging the animal in real-time in a non-destructive manner.

The invention discloses a small-sized desktop type magnetic resonance quality control and comprehensive test phantom which comprises a shell, wherein a test liquid and an independent modular test module are arranged in the shell; and the test module comprises a three-dimensional test module, a layer thickness test module, a relaxation test module, a contrast resolution test module, a location test module and a geometric distortion test module. The small-sized desktop type magnetic resonance quality control and comprehensive test phantom is characterized by further comprising a chemical shift test module, a movement test module and a coil probe uniformity and linearity test module. The phantom is applicable to the test of small-sized desktop type animal imaging magnetic resonance apparatuses and magnetic resonance imaging systems, and has the advantages of multiple parameters, high precision, combination type and flexible pore diameter design.

The invention provides improved red fluorescin and an application thereof and belongs to the field of protein engineering. The improved red fluorescin RFPSpark provided by the invention is obtained through reforming an amino acid sequence eqFP578 of red fluorescin derived from Entacmaea quadricolor and has an amino acid sequence shown in SEQ ID No. 7. Compared with wild type protein, the fluorescin has obviously different excitation and emission spectra and has the characteristics of higher fluorescence intensity, higher mature speed, better stability and longer wavelength; and compared with another modified protein FP650 of eqFP578, the fluorescent brightness of the red fluorescin provided by the invention is 3 times higher than that of the FP650 under equivalent test conditions. The invention further provides the application of the improved red fluorescin. The improved red fluorescin is applicable to analysis of cell marking, animal deep tissue and living animal imaging, multicolor application and the like and has a broad application prospect.

The invention relates to a magnetic resonance imaging superconducting magnet for animal imaging. The superconducting magnet is composed of superconducting main coils (2), superconducting axial shielding coils (3) and a superconducting radial shielding coil (4), wherein all the coils are axisymmetric solenoid coils using a symmetric axis (8) as a center axis. The superconducting main coils (2) are three pairs of solenoid coils with forward current, and the superconducting axial shielding coils (3) are a pair of solenoid coils with reverse current. The superconducting main coils (2) and the superconducting axial shielding coils (3) are positively symmetrically arranged about a symmetry plane (9). The superconducting radial shielding coil (4) is a solenoid coil with the reverse current, and the middle plane of the superconducting radial shielding coil is overlapped with the symmetry plane (9). The superconducting magnet generates highly-uniform magnetic field distribution at three concentric spherical areas (5, 6 and 7) with the diameters respectively being 80mm, 150mm and 200mm, and five Gaussian stray fields are respectively limited within the range of 1.5m and 2.2m ellipsoids in a radial direction and an axial direction.

The invention relates to an amphiphilic illuminant with aggregation induced emission characteristics and applications thereof. The illuminant is prepared by connecting a hydrophilia unit on a classical hydrophobicity unit of the classical aggregation induced emission characteristics (AIE), and can be applied to a fluorescent light chemical sensor and is used for preparing fluorescent light coloring agent which is used for coloring living cells and animal imaging fluorescent light. The amphiphilic coloring agent is specifically suitable for the fluorescent light mark on biopolymer, and can be used as a biocompatibility probe for AIE activation so that the amphiphilic coloring agent can be applied to clinic cancer imaging, diagnose and treatment.

The invention discloses a smart human body induction device applied to a toilet and an application method thereof. The smart human body induction device comprises a general switch, a millimeter wave detection module, a comparison module, a control module, a circuit protection module, a time delay module, an exhaust fan, a photosensitive induction module and a lighting lamp. The general switch canswitch on and switch off operation of the smart human body induction device. The millimeter wave detection module is used for sensing humans or animals in the toilet and performing imaging. The comparison module determines whether there is a human according to an imaging frame of an accessing animal detected by the millimeter wave detection module. The control module is used for controlling poweron and power off of the circuit protection module. The circuit protection module is used for protecting the normal operation of a circuit. The time delay module is used for timing and enabling time-delayed power off of an exhaust fan circuit. The photosensitive induction module is used for sensing the intensity of external light and controlling the switching on and off of the lighting lamp. The exhaust fan is used for exhausting air and circulating air. The lighting lamp is used for lighting. The smart human body induction device is convenient and practical, does not require manual operation,is energy-saving and environmentally-friendly, and reduces unnecessary loss.

The invention relates to the field of small animal imaging, solves the problems that in the prior art, the image resolution is low and the image acquisition time is long, provides a photon counting-type dynamic diffusion fluorescence tomography system which has high sensitivity and image resolution and achieves the purpose of dynamic diffusion fluorescence tomography with short measurement time. In order to achieve the purpose, the invention adopts the technical scheme as follows: the photon counting-type dynamic diffusion fluorescence tomography device comprises a light source system used for fluorescence excitation, an imaging chamber system used for fixing and moving a detected object, a light switch used for switching a detection passage, a light-filtering system used for filtering off excited light signals, a detection system used for detecting light signals, and a computer used for integrated control of an attenuator, the light switch, a motor-driven light filtering wheel, a photomultipler tube and a photon counting module as well as image reconstruction. The invention is mainly applied to small animal imaging.