Taxol microcapsule as well as preparation method and detection analysis method thereof
A technology for paclitaxel and microcapsules, applied in the field of paclitaxel microcapsules and preparation thereof, can solve the problems of low solubility of paclitaxel, limited clinical application and the like, and achieve the effects of strong production process and specificity, guaranteed quality and curative effect, and low cost
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[0025] Materials and reagents used: Ginkgo octenyl succinate starch ester, self-made in the laboratory; paclitaxel raw material, its purity > 99%, the production company is Nanjing Zelang Biotechnology Co., Ltd.; paclitaxel standard product, the production company is Shanghai A Latin Biochemical Technology Co., Ltd.; acetonitrile is chromatographically pure, methanol and absolute ethanol are analytically pure, and the production company is Shanghai Sinopharm Reagent Co., Ltd.; the water used in the experiment is distilled water.
[0026] Instruments and equipment used: AL204 analytical balance from Mettler-Toledo China Co., Ltd.; B-290 small spray dryer from Buchi Co., Ltd., Switzerland; experimental GYB high-pressure homogenizer from Shanghai Donghua Homogenizer Factory; High-performance liquid chromatograph from Waters Company in the United States; KQ3200 ultrasonic cleaning machine from Kunshan Ultrasound Instrument Co., Ltd.
[0027] Determination of paclitaxel content on ...
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