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A preparation method of a pharmaceutical composition for treating deafness

A composition and drug technology, applied in the direction of drug combination, pharmaceutical formula, active ingredient of hydroxy compound, etc., to achieve the effect of good treatment effect and high cure rate

Active Publication Date: 2020-11-06
刘艳平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in previous studies, there is no mature preparation method for drugs for the treatment of deafness

Method used

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  • A preparation method of a pharmaceutical composition for treating deafness
  • A preparation method of a pharmaceutical composition for treating deafness
  • A preparation method of a pharmaceutical composition for treating deafness

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0038] The purpose of this experiment is to verify the beneficial effect of frying on the preparation of Fu Cong Decoction.

[0039] Take the preparation method of composition 2 as an example:

[0040] In the experiment, the quality of the solute of the medicinal solution after the extraction of the medicinal materials was used as the detection index. The higher the quality of the solute, the greater the amount of active ingredients extracted, and it is speculated that the better the therapeutic effect of this preparation method.

[0041] 1. Preparation without frying: Weigh the following medicinal materials according to parts by weight: 60 parts by weight of astragalus, 10 parts by weight of angelica, 6 parts by weight of Chuanxiong, 15 parts by weight of red peony, 6 parts by weight of peach kernel, 6 parts by weight of safflower, cinnamon 5 parts by weight, 10 parts by weight of sumac, 6 parts by weight of leech, 20 parts by weight of wangbuliu, 20 parts by weight of magnet...

experiment example 2

[0055] The purpose of this experiment is to verify the beneficial effect of ultrasound on the preparation of Fucong Decoction.

[0056] Take the preparation method of composition 2 as an example:

[0057] In the experiment, the quality of the solute of the medicinal solution after the extraction of the medicinal materials was used as the detection index. The higher the quality of the solute, the greater the amount of active ingredients extracted, and it is speculated that the better the therapeutic effect of this preparation method.

[0058] 1. Preparation without ultrasonic method: Weigh the following medicinal materials in parts by weight: 60 parts by weight of astragalus, 10 parts by weight of angelica, 6 parts by weight of Chuanxiong, 15 parts by weight of red peony, 6 parts by weight of peach kernel, 6 parts by weight of safflower, 5 parts by weight of cinnamon Parts by weight, 10 parts by weight of sumac, 6 parts by weight of leech, 20 parts by weight of wangbuliu, 20 pa...

preparation example 1

[0082] The composition of composition 2: 30 parts by weight of astragalus, 5 parts by weight of angelica, 3 parts by weight of Chuanxiong, 7 parts by weight of red peony, 3 parts by weight of peach kernel, 3 parts by weight of safflower, 1 part by weight of cinnamon, 5 parts by weight of sumac, 3 parts by weight of leeches, 10 parts by weight of wangbuliu, and 10 parts by weight of magnetite, 100 g of medicinal materials were weighed in total.

[0083] Preparation:

[0084] (1) cleaning, 1000ml deionized water is prepared according to the conventional method and the deuterium abundance is 20×10 4 Atm% deuterium-depleted water, 0.0001% sodium selenite, after stirring evenly, carry out oxygenation treatment, when the oxygen content in water is 15ul / L, stop oxygenation; Soak peony, Chuanxiong, safflower, cinnamon, sumac, and Wangbuliu in deuterium-depleted water at 40°C, ultrasonically treat for 20 minutes, and ultrasonic power 280w; soak the crushed magnets and leeches at 60°C ...

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Abstract

The invention provides a preparation method of a medicine composition for treating deafness. The preparation method comprises the following steps: (1) cleaning of raw materials; (2) pretreatment and frying of the raw materials; (3) decoction; (4) adding of ethyl alcohol; (5) filtering; (6) concentration and packaging. An experiment shows that the medicinal material prepared on the basis of the method has a good treating effect on deafness caused by injury and deficiency of sensorineural hair cells, and is extremely high in curing rate.

Description

Technical field: [0001] The invention relates to a preparation method of a pharmaceutical composition for treating deafness. [0002] technical background: [0003] Deaf-mute patients refer to patients with both hearing and speech impairments. There are about 200 million deaf people in the world. There are more than 27 million deaf-mute people in my country, and 20,000 to 30,000 people are added every year. Once a family has a deaf-mute child, it will cause serious financial and ideological difficulties and pressure to the family. [0004] Sensorineural deafness is the degeneration and gradual disappearance of cochlear hair cells caused by exogenous or self-aging, and hearing loss and hearing loss caused by degenerative lesions of the stria vascularis, spiral ganglion, auditory nerve or auditory center. At present, this is considered as an irreversible lesion and there is no specific drug or conservative treatment that can completely restore hearing to patients with sensor...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8964A61K36/736A61K36/815A61P27/16A61K35/36A61K35/62A61K35/24A61K31/045A61K35/55A61K33/26
CPCA61K31/045A61K33/26A61K35/24A61K35/36A61K35/55A61K35/62A61K36/076A61K36/232A61K36/236A61K36/258A61K36/285A61K36/286A61K36/288A61K36/31A61K36/355A61K36/36A61K36/40A61K36/428A61K36/48A61K36/481A61K36/483A61K36/54A61K36/65A61K36/66A61K36/71A61K36/736A61K36/756A61K36/804A61K36/815A61K36/884A61K36/8964A61K2236/13A61K2236/331A61K2236/39A61K2300/00
Inventor 刘艳平
Owner 刘艳平
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