A kind of oral care composition for treating xerostomia and its application

Abstract

The invention discloses an oral care composition for treating xerostomia and the application of the oral care composition. The oral care composition consists of the following components in parts by weight: 0.1-1.5 parts of an olive extract, 0.1-1 part of lactoferrin microspheres and 0.1-5 parts of zinc oxide microspheres. The oral care composition can stimulate saliva secretion, relieve xerostomia, treat gingivitis and alleviate halitosis, can also achieve the effect of artificial saliva, realizes the effect of sterilizing the mouth, facilitates oral health of patients with xerostomia, and can be used for preparing oral care products for treating xerostomia and complication thereof.

Description

technical field [0001] The invention relates to the technical field of oral medicine and health care, in particular to a treatment technology for xerostomia, in particular to an oral care composition for treating xerostomia and its application. Background technique [0002] The production and secretion of saliva is critical to oral health and oral function. Due to the role of oral secretions in the colonization area of ​​oral microorganisms, the demineralization ability of teeth is increased, the remineralization ability is reduced, the retention of dentures is reduced, the mucosa is dehydrated and atrophied, and the clearance rate of substances in the oral cavity (including microorganisms and food residues) is reduced. Many complications of xerostomia occur due to the decrease of the effect of antibodies and enzymes in the oral environment, and the decrease of the lubricating effect on oral tissue. Common complications of xerostomia include: dental caries, candidiasis, muc...

AI Technical Summary

Problems solved by technology

However, if saliva production cannot be stimulated, then symptomatic treatment and prevention of possible complications of xerostomia are required, such as the use of humectants or saliva substitutes, which are mostly based on carboxymethylcellulose (CMC) as the main raw material, this product does not stimulate the non-Newtonian properties of saliva, and does not contain special antibacterial components (including antibodies), enzymes and other components in saliva

[0004] In the aspect of treating xerostomia, people have also adopted Chinese herbal medicines such as enzymes, xylitol, dendrobium and Polygonatum odoratum, etc., which have the effect of promoting body fluids, etc., as Patent No. CN105311404A relates to a formula for treating xerostomia in the elderly, the formula components and The respective weights are: 15 grams of dendrobium, 15 grams of Polygonatum odoratum, 18 grams of yam and 12 grams of sealwort, which can effectively stimulate the secretion function of salivary glands and play a role in promoting the secretion of saliva from salivary glands; the patent authorization announcement number CN101678217B relates to a kind of Compositions of oil, trimethylglycine and xylitol for the treatment of xerostomia and disorders associated therewith, which are very effective in increasing unstimulated saliva flow or reducing symptoms of xerostomia and improving the quality of life of patients Good effect; Patent Application Publication No. CN103561719A relates to an oral composition comprising extracts or mixtures thereof from Araliaceae, Zingiberaceae, Lamiaceae, Fabaceae, Solanaceae, Pomegranate, Compositae, which has the effect of relieving The effect of dry mouth, however, these Chinese herbal medicine extracts and saliva substitutes - biological enzymes are not easy to co-exist in oral care products, and active substances such as biological enzymes and Chinese herbal medicines for the treatment of dry mouth and active substances for the treatment of gingivitis and bad breath such as Chemical components, etc. tend to interact with each other, resulting in weakened effects

[0005] In short, the technology used in the treatment of xerostomia in the prior art is relatively single, either adding active substances that stimulate saliva to stimulate saliva secretion, but this technology has a weak effect on patients with salivary gland loss or loss of function; or adding similar The ingredients of saliva replace the effect of saliva to relieve dry mouth, but due to the short action time of toothpaste and the short retention time of active substances in the oral cavity, the effect is not significant

In addition, the existing technology has not taken into account dry mouth and complications of dry mouth, such as gingivitis, bad breath and other oral problems at the same time, and the treatment effect is single

Images