Method for preparing immobilized fungicide by grafting dendrimer with chlorine ball and its application

Abstract

The invention discloses a novel dendritic sterilization microsphere, and a preparation method and application thereof. The preparation method comprises the following steps: synthesizing and fixing third-generation PAMAM dendrimers through a Micheal addition reaction by taking a chloromethylated polystyrene microsphere as an initiating core, taking ethylene diamine and methyl acrylate as molecular chains and adopting a divergent method, and then performing quaternized modification by taking thiosemicarbazide as a functional group, so as to obtain the dendritic sterilization microsphere. The prepared dendritic bactericide is a novel material capable of performing high-efficient sterilization, the dendritic structure effectively increases the number of positive charges carried by the bactericide, improves the acting force of the bactericide on surface negative charges of bacteria, and increases the area of contact with the bacteria, so the aim of performing quick and high-efficient batch sterilization can be achieved. The third-generation PAMAM dendrimers are immobilized by taking a water-insoluble chloromethylated bead as an initiating core creatively, so the problem of residue of soluble bactericide in a water body can be effectively solved, and secondary pollution of traditional bactericide on the water body is avoided, thereby ensuring food safety, and expanding the application range of the bactericide.

Description

technical field [0001] The invention belongs to the technical field of synthesis and modification of dendritic macromolecules, and in particular relates to a novel dendritic bactericidal microsphere and its preparation method and application. Background technique [0002] Water is the source of life, the basis for human survival and development, and one of the important natural resources necessary for the development of the world economy. At present, the average amount of water available per capita in the world is 7,300 cubic meters per year, which has dropped by 37% compared with 1970. In the late 1980s, the actual freshwater utilization of the earth was about 300 billion m 3 per year, accounting for 1-3% of the total available water sources, but with the rapid development of industry and population in modern society, people's demand for water has increased by hundreds of millions, and the requirements for water quality have also become higher and higher. The amount of wa...

AI Technical Summary

Problems solved by technology

Sterilization refers to the killing of pathogenic bacteria in the object. There may be non-pathogenic bacteria such as spores or thermophilic bacteria in the object. The above two types of substances can achieve the effect of sterilization, but traditional fungicides also have insurmountable shortcomings : When the content of organic matter in the water source is slightly high, oxidizing fungicides such as chlorine gas sterilization will produce chlorinated organic matter, which can cause cancer; and the stability is not good, easy to decompose, the cost of transportation and storage is high, and there are potential threats such as explosion; in industrial water treatment , Poor peeling and washing effect on bacterial scale and slime

Since the use of water-soluble fungicides in water and liquid food will cause certain hazards, oxidizing fungicides will produce toxic by-products, and non-oxidizing fungicides are residual toxicity problems, and there is a risk of "secondary pollution"

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