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Application of dandelion extract in whitening and sunscreen cosmetics

A technology of dandelion extract and cosmetics, which is applied to the extraction of active ingredients in natural products and the field of natural cosmetics, can solve the problems of strong cytotoxicity, high price, poor cell membrane penetration, etc., and achieve the effect of inhibiting tyrosinase activity

Inactive Publication Date: 2017-08-15
INST OF CHEM IND OF FOREST PROD CHINESE ACAD OF FORESTRY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the whitening agents used in cosmetics at home and abroad are mainly kojic acid, fruit acid, arbutin, rhododendron alcohol, myricetin, puerarin, baicalein, tannic acid, kaempferol, etc., but due to the strong toxicity of these substances or cells , poor cell membrane penetration, weak stability or expensive defects, forcing people in the industry to turn to nature to find safe, stable and efficient tyrosinase inhibitors

Method used

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  • Application of dandelion extract in whitening and sunscreen cosmetics
  • Application of dandelion extract in whitening and sunscreen cosmetics
  • Application of dandelion extract in whitening and sunscreen cosmetics

Examples

Experimental program
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Effect test

Embodiment 1

[0030] ① Preparation of dandelion extract:

[0031] Take 6g of naturally dried dandelion and pulverize it, add 120mL of ethanol-water with a volume fraction of 50% to a glass flask, extract at room temperature with an ultrasonic power of 800W for 30min, suction filter while it is hot, and concentrate the collected solution by rotary evaporation at 45°C. The concentrate was collected, and the concentrate was vacuum freeze-dried to obtain a dandelion extract with a solid content of 2.25 g.

[0032] ② Evaluation of tyrosinase inhibitory activity and UV absorption ability of dandelion extract:

[0033] Dissolve the prepared dandelion extract in DMSO, configure different concentration gradients, 1, 0.5, 0.25, 0.125 and 0.0625 mg / mL, and then configure different gradient concentrations of 3.0, 1.5, 0.75, 0.375 and 0.1875 mg / mL kojic acid as positive control. Measure the absorbance at the absorption wavelength of 365nm (UVA) and 300nm (UVB), respectively, and then linearly fit to o...

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Abstract

The invention discloses an application of dandelion extract in whitening and sunscreen cosmetics. A method for preparing the dandelion extract comprises the following steps: carrying out extraction on dandelion used as a raw material in an ethanol-water mixed system used as an extraction solvent under the assistance of ultrasonic waves, and drying the obtained extract liquid to obtain the dandelion extract. The dandelion extract has an inhibition effect on tyrosinase, can absorb UVA 365 nm and UVB 300 nm in solar ultraviolet lights, and can be used in the whitening and sunscreen cosmetics having tyrosinase inhibition activity and ultraviolet resistance.

Description

technical field [0001] The invention relates to the field of extraction of active ingredients from natural products and natural cosmetics, in particular to the application of a dandelion extract in the preparation of whitening and sunscreen cosmetics. Background technique [0002] With the aggravation of environmental pollution and the deepening of the destruction of the atmosphere, the impact of ultraviolet rays in solar radiation on the skin is becoming more and more serious. At the same time, with the rapid development of my country's economy and society, people's health awareness of skin sunscreen and whitening is gradually increasing, and there are a variety of whitening and sunscreen cosmetics. . [0003] UVA (320-400nm) and UVB (280-320nm) in the middle and long ultraviolet bands in the solar spectrum will cause harm to human health. Long-term exposure to sunlight will burn the skin in mild cases, causing skin peeling and pigmentation; in severe cases, it will cause ph...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61Q19/02A61Q17/04
CPCA61K8/97A61K2800/782A61Q17/04A61Q19/02
Inventor 黄立新谢普军张彩虹丁莎莎邓叶俊
Owner INST OF CHEM IND OF FOREST PROD CHINESE ACAD OF FORESTRY
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